Search Results - "Chernyak, B."

NETosis: Molecular Mechanisms, Role in Physiology and Pathology by Vorobjeva, N. V., Chernyak, B. V.

“…NETosis is a program for formation of neutrophil extracellular traps (NETs), which consist of modified chromatin decorated with bactericidal proteins from…”
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COVID-19 and Oxidative Stress by Chernyak, B. V., Popova, E. N., Prikhodko, A. S., Grebenchikov, O. A., Zinovkina, L. A., Zinovkin, R. A.

“…Pathogenesis of the novel coronavirus infection COVID-19 is the subject of active research around the world. COVID-19 caused by the SARS-CoV-2 is a complex…”
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Mitochondrial Transplantation: A Critical Analysis by Chernyak, B. V.

“…“Mitochondrial transplantation” refers to a procedure for introducing isolated mitochondria into a damaged area of a heart or other organ. A considerable…”
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Mitoptosis, Twenty Years After by Lyamzaev, K. G., Knorre, D. A., Chernyak, B. V.

“…In 1999 V. P. Skulachev proposed the term “mitoptosis” to refer to the programmed elimination of mitochondria in living cells. According to the initial…”
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Mitochondrion-targeted antioxidant SkQ1 prevents rapid animal death caused by highly diverse shocks by Skulachev, V. P., Vyssokikh, M. Yu, Chernyak, B. V., Averina, O. A., Andreev-Andrievskiy, A. A., Zinovkin, R. A., Lyamzaev, K. G., Marey, M. V., Egorov, M. V., Frolova, O. J., Zorov, D. B., Skulachev, M. V., Sadovnichii, V. A.

“…The response to stress involves the activation of pathways leading either to protection from the stress origin, eventually resulting in development of stress…”
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Role of reactive oxygen species in mast cell degranulation by Chelombitko, M. A., Fedorov, A. V., Ilyinskaya, O. P., Zinovkin, R. A., Chernyak, B. V.

“…Mast cells are a heterogeneous multifunctional cellular population that promotes connective tissue homeostasis by slow release of biologically active…”
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Mitochondrial-targeted plastoquinone derivatives. Effect on senescence and acute age-related pathologies by Skulachev, M V, Antonenko, Y N, Anisimov, V N, Chernyak, B V, Cherepanov, D A, Chistyakov, V A, Egorov, M V, Kolosova, N G, Korshunova, G A, Lyamzaev, K G, Plotnikov, E Y, Roginsky, V A, Savchenko, A Y, Severina, I I, Severin, F F, Shkurat, T P, Tashlitsky, V N, Shidlovsky, K M, Vyssokikh, M Y, Zamyatnin, Jr, A A, Zorov, D B, Skulachev, V P

“…Plastoquinone, a very effective electron carrier and antioxidant of chloroplasts, was conjugated with decyltriphenylphosphonium to obtain a cation easily…”
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Mitochondria-targeted plastoquinone derivatives as tools to interrupt execution of the aging program. 1. Cationic plastoquinone derivatives: Synthesis and in vitro studies by Antonenko, Y. N, Avetisyan, A. V, Bakeeva, L. E, Chernyak, B. V, Chertkov, V. A, Domnina, L. V, Ivanova, O. Yu, Izyumov, D. S, Khailova, L. S, Klishin, S. S, Korshunova, G. A, Lyamzaev, K. G, Muntyan, M. S, Nepryakhina, O. K, Pashkovskaya, A. A, Pletjushkina, O. Yu, Pustovidko, A. V, Roginsky, V. A, Rokitskaya, T. I, Ruuge, E. K, Saprunova, V. B, Severina, I. I, Simonyan, R. A, Skulachev, I. V, Skulachev, M. V, Sumbatyan, N. V, Sviryaeva, I. V, Tashlitsky, V. N, Vassiliev, J. M, Vyssokikh, M. Yu, Yaguzhinsky, L. S, Zamyatnin, A. A. Jr, Skulachev, V. P

“…Synthesis of cationic plastoquinone derivatives (SkQs) containing positively charged phosphonium or rhodamine moieties connected to plastoquinone by decane or…”
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Does Oxidation of Mitochondrial Cardiolipin Trigger a Chain of Antiapoptotic Reactions? by Mulkidjanian, A. Y., Shalaeva, D. N., Lyamzaev, K. G., Chernyak, B. V.

“…Oxidative stress causes selective oxidation of cardiolipin (CL), a fourtail lipid specific for the inner mitochondrial membrane. Interaction with oxidized CL…”
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The Role of Protein Kinase C Isoforms in the Formation of Neutrophil Extracellular Traps by Vorobjeva, N. V., Vakhlyarskaya, S. S., Chernyak, B. V.

“…Neutrophils release decondensed nuclear chromatin or neutrophil extracellular traps (NET) in response to a great number of physiological and pharmacological…”
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NADPH Oxidase Modulates Ca2+-Dependent Formation of Neutrophil Extracellular Traps by Vorobjeva, N. V., Chernyak, B. V.

“…— Chronic granulomatous disease (CGD) is a severe hereditary immunodeficiency associated with recurrent bacterial and fungal infections as well as aberrant…”
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Mitochondria-targeted antioxidant SkQ1 (10-(6′-plastoquinonyl)decyltriphenylphosphonium bromide) inhibits mast cell degranulation in vivo and in vitro by Chelombitko, M. A., Averina, O. A., Vasilyeva, T. V., Pletiushkina, O. Yu, Popova, E. N., Fedorov, A. V., Chernyak, B. V., Shishkina, V. S., Ilinskaya, O. P.

“…The therapeutic effect of mitochondria-targeted antioxidant 10-(6′-plastoquinonyl)decyltriphenylphosphonium bromide (SkQ1) in experimental models of acute…”
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Mitochondria-targeted antioxidant SkQR1 reduces TNF-induced endothelial permeability in vitro by Galkin, I. I., Pletjushkina, O. Yu, Zinovkin, R. A., Zakharova, V. V., Chernyak, B. V., Popova, E. N.

“…Prolonged or excessive increase in the circulatory level of proinflammatory tumor necrosis factor (TNF) leads to abnormal activation and subsequent damage to…”
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Protective Effects of Mitochondria-Targeted Antioxidant SkQ in Aqueous and Lipid Membrane Environments by Antonenko, Y. N., Roginsky, V. A., Pashkovskaya, A. A., Rokitskaya, T. I., Kotova, E. A., Zaspa, A. A., Chernyak, B. V., Skulachev, V. P.

“…The antioxidant activity of mitochondria-targeted small molecules, SkQ1 and MitoQ (conjugates of a lipophilic decyltriphenylphosphonium cation with an…”
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Effect of oxidative stress on dynamics of mitochondrial reticulum by Pletjushkina, O.Yu, Lyamzaev, K.G., Popova, E.N., Nepryakhina, O.K., Ivanova, O.Yu, Domnina, L.V., Chernyak, B.V., Skulachev, V.P.

“…Fission of the mitochondrial reticulum (the thread–grain transition) and following gathering of mitochondria in the perinuclear area are induced by oxidative…”
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Mitochondria-targeted plastoquinone derivatives as tools to interrupt execution of the aging program. 3. Inhibitory effect of SkQ1 on tumor development from p53-deficient cells by Agapova, L. S, Chernyak, B. V, Domnina, L. V, Dugina, V. B, Efimenko, A. Yu, Fetisova, E. K, Ivanova, O. Yu, Kalinina, N. I, Khromova, N. V, Kopnin, B. P, Kopnin, P. B, Korotetskaya, M. V, Lichinitser, M. R, Lukashev, A. L, Pletjushkina, O. Yu, Popova, E. N, Skulachev, M. V, Shagieva, G. S, Stepanova, E. V, Titova, E. V, Tkachuk, V. A, Vasiliev, J. M, Skulachev, V. P

“…It was proposed that increased level of mitochondrial reactive oxygen species (ROS), mediating execution of the aging program of an organism, could also be…”
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Low concentrations of uncouplers of oxidative phosphorylation prevent inflammatory activation of endothelial cells by tumor necrosis factor by Romaschenko, V. P., Zinovkin, R. A., Galkin, I. I., Zakharova, V. V., Panteleeva, A. A., Tokarchuk, A. V., Lyamzaev, K. G., Pletjushkina, O. Yu, Chernyak, B. V., Popova, E. N.

“…In endothelial cells, mitochondria play an important regulatory role in physiology as well as in pathophysiology related to excessive inflammation. We have…”
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Molecular Dynamics Modeling of the Interaction of Cationic Fluorescent Lipid Peroxidation-Sensitive Probes with the Mitochondrial Membrane by Nesterenko, A. M., Kholina, E. G., Lyamzaev, K. G., Mulkidjanian, A. Ya, Chernyak, B. V.

“…Cardiolipin (CL) plays a central role in lipid peroxidation (LPO) of the mitochondrial inner membrane due to higher content of unsaturated fatty acids in CL in…”
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Mitochondria-targeted antioxidants prevent TNFα-induced endothelial cell damage by Galkin, I. I., Pletjushkina, O. Yu, Zinovkin, R. A., Zakharova, V. V., Birjukov, I. S., Chernyak, B. V., Popova, E. N.

“…Increased serum level of tumor necrosis factor α (TNFα) causes endothelial dysfunction and leads to serious vascular pathologies. TNFα signaling is known to…”
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Mitochondria as source of reactive oxygen species under oxidative stress. Study with novel mitochondria-targeted antioxidants — the “Skulachev-ion” derivatives by Izyumov, D. S, Domnina, L. V, Nepryakhina, O. K, Avetisyan, A. V, Golyshev, S. A, Ivanova, O. Y, Korotetskaya, M. V, Lyamzaev, K. G, Pletjushkina, O. Y, Popova, E. N, Chernyak, B. V

“…Production of reactive oxygen species (ROS) in mitochondria was studied using the novel mitochondria-targeted antioxidants (SkQ) in cultures of human cells. It…”
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