Search Results - "Chernogubova, Ekaterina"

H19 Induces Abdominal Aortic Aneurysm Development and Progression by Li, Daniel Y, Busch, Albert, Jin, Hong, Chernogubova, Ekaterina, Pelisek, Jaroslav, Karlsson, Joakim, Sennblad, Bengt, Liu, Shengliang, Lao, Shen, Hofmann, Patrick, Bäcklund, Alexandra, Eken, Suzanne M, Roy, Joy, Eriksson, Per, Dacken, Brian, Ramanujam, Deepak, Dueck, Anne, Engelhardt, Stefan, Boon, Reinier A, Eckstein, Hans-Henning, Spin, Joshua M, Tsao, Philip S, Maegdefessel, Lars

“…BACKGROUND—Long noncoding RNAs (lncRNAs) have emerged as critical molecular regulators in various biological processes and diseases. Here we sought to identify…”
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Local Delivery of miR-21 Stabilizes Fibrous Caps in Vulnerable Atherosclerotic Lesions by Jin, Hong, Li, Daniel Y., Chernogubova, Ekaterina, Sun, Changyan, Busch, Albert, Eken, Suzanne M., Saliba-Gustafsson, Peter, Winter, Hanna, Winski, Greg, Raaz, Uwe, Schellinger, Isabel N., Simon, Nancy, Hegenloh, Renate, Matic, Ljubica Perisic, Jagodic, Maja, Ehrenborg, Ewa, Pelisek, Jaroslav, Eckstein, Hans-Henning, Hedin, Ulf, Backlund, Alexandra, Maegdefessel, Lars

“…miRNAs are potential regulators of carotid artery stenosis and concordant vulnerable atherosclerotic plaques. Hence, we analyzed miRNA expression in laser…”
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MicroRNA-210 Enhances Fibrous Cap Stability in Advanced Atherosclerotic Lesions by Eken, Suzanne M, Jin, Hong, Chernogubova, Ekaterina, Li, Yuhuang, Simon, Nancy, Sun, Changyan, Korzunowicz, Greg, Busch, Albert, Bäcklund, Alexandra, Österholm, Cecilia, Razuvaev, Anton, Renné, Thomas, Eckstein, Hans Henning, Pelisek, Jaroslav, Eriksson, Per, González Díez, María, Perisic Matic, Ljubica, Schellinger, Isabel N, Raaz, Uwe, Leeper, Nicholas J, Hansson, Göran K, Paulsson-Berne, Gabrielle, Hedin, Ulf, Maegdefessel, Lars

“…RATIONALE:In the search for markers and modulators of vascular disease, microRNAs (miRNAs) have emerged as potent therapeutic targets. OBJECTIVE:To investigate…”
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Local MicroRNA Modulation Using a Novel Anti-miR-21–Eluting Stent Effectively Prevents Experimental In-Stent Restenosis by Wang, Dong, Deuse, Tobias, Stubbendorff, Mandy, Chernogubova, Ekaterina, Erben, Reinhold G, Eken, Suzanne M, Jin, Hong, Li, Yuhuang, Busch, Albert, Heeger, Christian-H, Behnisch, Boris, Reichenspurner, Hermann, Robbins, Robert C, Spin, Joshua M, Tsao, Philip S, Schrepfer, Sonja, Maegdefessel, Lars

“…OBJECTIVE—Despite advances in stent technology for vascular interventions, in-stent restenosis (ISR) because of myointimal hyperplasia remains a major…”
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Four Surgical Modifications to the Classic Elastase Perfusion Aneurysm Model Enable Haemodynamic Alterations and Extended Elastase Perfusion by Busch, Albert, Chernogubova, Ekaterina, Jin, Hong, Meurer, Felix, Eckstein, Hans-Henning, Kim, Mia, Maegdefessel, Lars

“…Abdominal aortic aneurysm (AAA) is an individual and socioeconomic burden in today's ageing society. Treatment relies on surgical exclusion of the dilated…”
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The Role of MicroRNA-21 in Venous Neointimal Hyperplasia: Implications for Targeting miR-21 for VNH Treatment by Kilari, Sreenivasulu, Cai, Chuanqi, Zhao, Chenglei, Sharma, Amit, Chernogubova, Ekaterina, Simeon, Michael, Wu, Chin-Cheng, Song, Hsiang-Lin, Maegdefessel, Lars, Misra, Sanjay

“…The molecular mechanism of hemodialysis access arteriovenous fistula (AVF) failure due to venous neointimal hyperplasia (VNH) is not known. The role of…”
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Norepinephrine Increases Glucose Transport in Brown Adipocytes via β3-Adrenoceptors through a cAMP, PKA, and PI3-Kinase-Dependent Pathway Stimulating Conventional and Novel PKCs by Chernogubova, Ekaterina, Cannon, Barbara, Bengtsson, Tore

“…To identify the signaling pathways that mediate the adrenergic stimulation of glucose uptake in brown adipose tissue, we used mouse brown adipocytes in…”
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β₁-Adrenergic receptors increase UCP1 in human MADS brown adipocytes and rescue cold-acclimated β₃-adrenergic receptor-knockout mice via nonshivering thermogenesis by Mattsson, Charlotte L, Csikasz, Robert I, Chernogubova, Ekaterina, Yamamoto, Daniel L, Hogberg, Helena T, Amri, Ez-Zoubir, Hutchinson, Dana S, Bengtsson, Tore

“…With the finding that brown adipose tissue is present and negatively correlated to obesity in adult man, finding the mechanism(s) of how to activate brown…”
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Mustn1 is a smooth muscle cell-secreted microprotein that modulates skeletal muscle extracellular matrix composition by Ducommun, Serge, Jannig, Paulo R., Cervenka, Igor, Murgia, Marta, Mittenbühler, Melanie J., Chernogubova, Ekaterina, Dias, José M., Jude, Baptiste, Correia, Jorge C., Van Vranken, Jonathan G., Ocana-Santero, Gabriel, Porsmyr-Palmertz, Margareta, McCann Haworth, Sarah, Martínez-Redondo, Vicente, Liu, Zhengye, Carlström, Mattias, Mann, Matthias, Lanner, Johanna T., Teixeira, Ana I., Maegdefessel, Lars, Spiegelman, Bruce M., Ruas, Jorge L.

“…Skeletal muscle plasticity and remodeling are critical for adapting tissue function to use, disuse, and regeneration. The aim of this study was to identify…”
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Apolipoprotein E (ApoE) Rescues the Contractile Smooth Muscle Cell Phenotype in Popliteal Artery Aneurysm Disease by Pauli, Jessica, Reisenauer, Tessa, Winski, Greg, Sachs, Nadja, Chernogubova, Ekaterina, Freytag, Hannah, Otto, Christoph, Reeps, Christian, Eckstein, Hans-Henning, Scholz, Claus-Jürgen, Maegdefessel, Lars, Busch, Albert

“…Popliteal artery aneurysm (PAA) is the most frequent peripheral aneurysm, primarily seen in male smokers with a prevalence below 1%. This exploratory study…”
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miR-29b Mediates the Chronic Inflammatory Response in Radiotherapy-Induced Vascular Disease by Eken, Suzanne M., MD, PhD, Christersdottir, Tinna, MD, Winski, Greg, MD, Sangsuwan, Traimate, MSc, Jin, Hong, MD, PhD, Chernogubova, Ekaterina, PhD, Pirault, John, PhD, Sun, Changyan, MSc, Simon, Nancy, MSc, Winter, Hanna, MSc, Backlund, Alexandra, PhD, Haghdoost, Siamak, PhD, Hansson, Göran K., MD, PhD, Halle, Martin, MD, PhD, Maegdefessel, Lars, MD, PhD

“…Visual Abstract…”
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Aneurysm miRNA Signature Differs, Depending on Disease Localization and Morphology by Busch, Albert, Busch, Martin, Scholz, Claus-Jürgen, Kellersmann, Richard, Otto, Christoph, Chernogubova, Ekaterina, Maegdefessel, Lars, Zernecke, Alma, Lorenz, Udo

“…Limited comprehension of aneurysm pathology has led to inconclusive results from clinical trials. miRNAs are key regulators of post-translational gene…”
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Lenvatinib halts aortic aneurysm growth by restoring smooth muscle cell contractility by Busch, Albert, Pauli, Jessica, Winski, Greg, Bleichert, Sonja, Chernogubova, Ekaterina, Metschl, Susanne, Winter, Hanna, Trenner, Matthias, Wiegering, Armin, Otto, Christoph, Fischer, Johannes, Reiser, Judith, Werner, Julia, Roy, Joy, Brostjan, Christine, Knappich, Christoph, Eckstein, Hans-Henning, Paloschi, Valentina, Maegdefessel, Lars

“…Abdominal aortic aneurysm (AAA) is a disease with high morbidity and mortality, especially when ruptured. The rationale of this study was to evaluate the…”
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α1- and β1-Adrenoceptor Signaling Fully Compensates for β3-Adrenoceptor Deficiency in Brown Adipocyte Norepinephrine-Stimulated Glucose Uptake by Chernogubova, Ekaterina, Hutchinson, Dana S, Nedergaard, Jan, Bengtsson, Tore

“…To assess the relative roles and potential contribution of adrenergic receptor subtypes other than the β3-adrenergic receptor in norepinephrine-mediated…”
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MicroRNA-15A is a Potential Circulating Biomarker of Abdominal Aortic Aneurysm with Both Diagnostic and Prognostic Properties by Winski, Greg, Eken, Suzanne M., Chernogubova, Ekaterina, Busch, Albert, Jin, Hong, Winter, Hanna, Spin, Joshua M., Bäcklund, Alexandra, Tsao, Philip S., Maegdefessel, Lars

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Variants in the coagulation factor 2 receptor (F2R) gene influence the risk of myocardial infarction in men through an interaction with interleukin 6 serum levels by Gigante, Bruna, Vikström, Max, Meuzelaar, Linda Strömqvist, Chernogubova, Ekaterina, Silveira, Angela, Hooft, Ferdinand Van't, Hamsten, Anders, de Faire, Ulf

“…Thrombin-activated factor 2 receptor (F2R) links thrombosis to inflammation modulating interleukin (IL)6 synthesis. We have investigated the role of F2R…”
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Making Sense in Antisense : Therapeutic Potential of Noncoding RNAs in Diabetes-Induced Vascular Dysfunction by Eken, Suzanne M., Jin, Hong, Chernogubova, Ekaterina, Maegdefessel, Lars

“…The rapid rise of type II diabetes mellitus and its accompanying vascular complications call for novel approaches in unravelling its pathophysiological…”
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Agonist effects of zinterol at the mouse and human β3-adrenoceptor by Hutchinson, Dana S., Chernogubova, Ekaterina, Sato, Masaaki, Summers, Roger J., Bengtsson, Tore

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Long Noncoding RNA MIAT Controls Advanced Atherosclerotic Lesion Formation and Plaque Destabilization by Fasolo, Francesca, Jin, Hong, Winski, Greg, Chernogubova, Ekaterina, Pauli, Jessica, Winter, Hanna, Li, Daniel Y., Glukha, Nadiya, Bauer, Sabine, Metschl, Susanne, Wu, Zhiyuan, Koschinsky, Marlys L., Reilly, Muredach, Pelisek, Jaroslav, Kempf, Wolfgang, Eckstein, Hans-Henning, Soehnlein, Oliver, Matic, Ljubica, Hedin, Ulf, Bäcklund, Alexandra, Bergmark, Claes, Paloschi, Valentina, Maegdefessel, Lars

“…Long noncoding RNAs (lncRNAs) are important regulators of biological processes involved in vascular tissue homeostasis and disease development. The present…”
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Abstract 353: Phenotypic Switching Of Vascular Smooth Muscle Cells Is Regulated By ApoE And A Potential Therapeutic Target In Popliteal Aneurysms by Reisenauer, Tessa, Pauli, Jessica, Paloschi, Valentina, Chernogubova, Ekaterina, Scholz, Claus, Reeps, Christian, Eckstein, Hans-Henning, Maegdefessel, Lars, Busch, Albert

“…IntroductionPopliteal artery aneurysm (PAA) is an individually highly fatal disease, causing ischemia and eventual major amputation, mainly in 50-70-year-old…”
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