Search Results - "Chernikov, Oleg V."

Spatial Structure of Lectin from the Mussel Mytilus trossulus : In-Sights from Molecular Modelling and Practical Proof by Filshtein, Alina P, Chikalovets, Irina V, Mizgina, Tatyana O, Lukyanov, Pavel A, Hua, Kuo-Feng, Chernikov, Oleg V

“…Most proteins have the ability to self-associate into homooligomeric protein complexes, which consist of two or more identical subunits. Today, modern methods…”
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Editorial: NLRP3 Inflammasome: Regulatory Mechanisms, Role in Health and Disease and Therapeutic Potential by Chernikov, Oleg V, Moon, Jong-Seok, Chen, Ann, Hua, Kuo-Feng

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Exploring Candesartan, an angiotensin II receptor antagonist, as a novel inhibitor of NLRP3 inflammasome: alleviating inflammation in Neisseria gonorrhoeae infection by Lin, Wen-Yu, Tsui, Jin-Lian, Chiu, Hsiao-Wen, Wong, Wei-Ting, Wu, Chun-Hsien, Hsu, Hsien-Ta, Ho, Chen-Lung, Yeh, Shan-Pei, Rao, Yerra Koteswara, Chen, Ann, Wang, Chien-Chun, Hsu, Chung-Hua, Chernikov, Oleg V, Hua, Kuo-Feng, Li, Lan-Hui

“…Gonorrhea, induced by Neisseria gonorrhoeae infection, stands as a prevalent sexually transmitted inflammatory disease globally. Our earlier research…”
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New l-Rhamnose-Binding Lectin from the Bivalve Glycymeris yessoensis : Purification, Partial Structural Characterization and Antibacterial Activity by Mizgina, Tatyana O, Chikalovets, Irina V, Bulanova, Tatyana A, Molchanova, Valentina I, Filshtein, Alina P, Ziganshin, Rustam H, Rogozhin, Eugene A, Shilova, Nadezhda V, Chernikov, Oleg V

“…In this study, a new l-rhamnose-binding lectin (GYL-R) from the hemolymph of bivalve was purified using affinity and ion-exchange chromatography and…”
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Molecular Cloning and Characteristics of a Lectin from the Bivalve Glycymeris yessoensis by Mizgina, Tatyana O, Baldaev, Sergey N, Likhatskaya, Galina N, Molchanova, Valentina I, Kokoulin, Maxim S, Filshtein, Alina P, Rogozhin, Eugene A, Chikalovets, Irina V, Isaeva, Marina P, Chernikov, Oleg V

“…C-type lectins (CTLs) are a family of carbohydrate-binding proteins that mediate multiple biological events, including adhesion between cells, the turnover of…”
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Identification and Characterization of a Novel Lectin from the Clam Glycymeris yessoensis and Its Functional Characterization under Microbial Stimulation and Environmental Stress by Mizgina, Tatyana O, Chikalovets, Irina V, Molchanova, Valentina I, Ziganshin, Rustam H, Chernikov, Oleg V

“…Lectin from the bivalve (GYL) was purified by affinity chromatography on porcine stomach mucin-Sepharose. GYL is a dimeric protein with a molecular mass of 36…”
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Structure and in vitro Bioactivity against Cancer Cells of the Capsular Polysaccharide from the Marine Bacterium Psychrobacter marincola by Kokoulin, Maxim S, Kuzmich, Alexandra S, Romanenko, Lyudmila A, Chikalovets, Irina V, Chernikov, Oleg V

“…Psychrobacter KMM 277 is a psychrophilic Gram-negative bacterium that has been isolated from the internal tissues of an ascidian sp. Here, we report the…”
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Ginsenoside M1 Induces Apoptosis and Inhibits the Migration of Human Oral Cancer Cells by Lee, Yu-Chieh, Wong, Wei-Ting, Li, Lan-Hui, Chu, Lichieh Julie, Menon, Mridula P, Ho, Chen-Lung, Chernikov, Oleg V, Lee, Sheau-Long, Hua, Kuo-Feng

“…Oral squamous cell carcinoma (OSCC) accounts for 5.8% of all malignancies in Taiwan, and the incidence of OSCC is on the rise. OSCC is also a common malignancy…”
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A GalNAc/Gal-specific lectin from the sea mussel Crenomytilus grayanus modulates immune response in macrophages and in mice by Chernikov, Oleg V., Wong, Wei-Ting, Li, Lan-Hui, Chikalovets, Irina V., Molchanova, Valentina I., Wu, Shih-Hsiung, Liao, Jiahn-Haur, Hua, Kuo-Feng

“…A GalNAc/Gal-specific lectin (CGL) from the edible mussel Crenomytilus grayanus has been demonstrated to exhibit antibacterial properties. However, the…”
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Repositioning of the Angiotensin II Receptor Antagonist Candesartan as an Anti-Inflammatory Agent With NLRP3 Inflammasome Inhibitory Activity by Lin, Wen-Yu, Li, Lan-Hui, Hsiao, Ya-Yun, Wong, Wei-Ting, Chiu, Hsiao-Wen, Hsu, Hsien-Ta, Peng, Yi-Jen, Ho, Chen-Lung, Chernikov, Oleg V, Cheng, Shu-Meng, Yang, Shih-Ping, Hua, Kuo-Feng

“…Aberrant activation of the NLRP3 inflammasome promotes the pathogenesis of many inflammatory diseases. The development of the NLRP3 inflammasome inhibitors…”
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A Synthetic Small Molecule F240B Decreases NLRP3 Inflammasome Activation by Autophagy Induction by Wu, Chun-Hsien, Gan, Chin Heng, Li, Lan-Hui, Chang, Jen-Che, Chen, Shin-Tai, Menon, Mridula P, Cheng, Shu-Meng, Yang, Shih-Ping, Ho, Chen-Lung, Chernikov, Oleg V, Lin, Chi-Hung, Lam, Yulin, Hua, Kuo-Feng

“…Conjugated polyenes are a class of widely occurring natural products with various biological functions. We previously identified 4-hydroxy auxarconjugatin B…”
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Critical Role for the NLRP3 Inflammasome in Mediating IL-1β Production in Shigella sonnei -Infected Macrophages by Li, Lan-Hui, Chen, Tzu-Ling, Chiu, Hsiao-Wen, Hsu, Chung-Hua, Wang, Chien-Chun, Tai, Tzu-Ting, Ju, Tz-Chuen, Chen, Fang-Hsin, Chernikov, Oleg V, Tsai, Wen-Chiuan, Hua, Kuo-Feng

“…is one of the leading bacterial causes of diarrhea worldwide, affecting more than 165 million people annually. Among the serotypes of is physiologically unique…”
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Corrigendum: A Synthetic Small Molecule F240B Decreases NLRP3 Inflammasome Activation by Autophagy Induction by Wu, Chun-Hsien, Gan, Chin Heng, Li, Lan-Hui, Chang, Jen-Che, Chen, Shin-Tai, Menon, Mridula P, Cheng, Shu-Meng, Yang, Shih-Ping, Ho, Chen-Lung, Chernikov, Oleg V, Lin, Chi-Hung, Lam, Yulin, Hua, Kuo-Feng

“…[This corrects the article DOI: 10.3389/fimmu.2020.607564.]…”
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Mechanistic Insight Into the Activation of the NLRP3 Inflammasome by Neisseria gonorrhoeae in Macrophages by Li, Lan-Hui, Lin, Jia-Sing, Chiu, Hsiao-Wen, Lin, Wen-Yu, Ju, Tz-Chuen, Chen, Fang-Hsin, Chernikov, Oleg V, Liu, May-Lan, Chang, Jen-Che, Hsu, Chung-Hua, Chen, Ann, Ka, Shuk-Man, Gao, Hong-Wei, Hua, Kuo-Feng

“…Gonorrhea is a type III legal communicable disease caused by (NG), one of the most common sexually transmitted bacteria worldwide. NG infection can cause…”
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The leaves of the seasoning plant Litsea cubeba inhibit the NLRP3 inflammasome and ameliorate dextran sulfate sodium-induced colitis in mice by Wong, Wei-Ting, Wu, Chun-Hsien, Li, Lan-Hui, Hung, De-Yu, Chiu, Hsiao-Wen, Hsu, Hsien-Ta, Ho, Chen-Lung, Chernikov, Oleg V., Cheng, Shu-Meng, Yang, Shih-Ping, Chung, Chih-Hsin, Hua, Kuo-Feng, Wang, Chin-Fah

“…The intracellular sensor NACHT, LRR, and PYD domain-containing protein 3 (NLRP3) inflammasome controls caspase-1 activity and the maturation and release of the…”
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Immunomodulatory Properties of Polysaccharides from the Coral Pseudopterogorgia americana in Macrophages by Chernikov, Oleg V, Chiu, Hsiao-Wen, Li, Lan-Hui, Kokoulin, Maxim S, Molchanova, Valentina I, Hsu, Hsien-Ta, Ho, Chen-Lung, Hua, Kuo-Feng

“…Polysaccharides from marine organisms produce an important regulatory effect on the mammalian immune system. In this study, the immunomodulatory properties of…”
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Synthetic 4-Hydroxy Auxarconjugatin B, a Novel Autophagy Inducer, Attenuates Gouty Inflammation by Inhibiting the NLRP3 Inflammasome by Hsieh, Chih-Yu, Li, Lan-Hui, Lam, Yulin, Fang, Zhanxiong, Gan, Chin Heng, Rao, Yerra Koteswara, Chiu, Hsiao-Wen, Wong, Wei-Ting, Ju, Tz-Chuen, Chen, Fang-Hsin, Chernikov, Oleg V, Liu, May-Lan, Hsu, Chung-Hua, Hua, Kuo-Feng

“…Gouty arthritis results from the generation of uric acid crystals within the joints. These uric acid crystals activate the NACHT, LRR and PYD…”
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The Unusual Lipid A Structure and Immunoinhibitory Activity of LPS from Marine Bacteria Echinicola pacifica KMM 6172T and Echinicola vietnamensis KMM 6221T by Pither, Molly Dorothy, Mantova, Giuseppe, Scaglione, Elena, Pagliuca, Chiara, Colicchio, Roberta, Vitiello, Mariateresa, Chernikov, Oleg V., Hua, Kuo-Feng, Kokoulin, Maxim S., Silipo, Alba, Salvatore, Paola, Molinaro, Antonio, Di Lorenzo, Flaviana

“…Gram-negative bacteria experiencing marine habitats are constantly exposed to stressful conditions dictating their survival and proliferation. In response to…”
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А new Gal/GalNAc-specific lectin from the mussel Mytilus trossulus: Structure, tissue specificity, antimicrobial and antifungal activity by Chikalovets, Irina V., Kovalchuk, Svetlana N., Litovchenko, Alina P., Molchanova, Valentina I., Pivkin, Mikhail V., Chernikov, Oleg V.

“…In the present study, a new Gal/GalNAc specific lectin from the mussel Mytilus trossulus (designated as MTL) was identified, and its expression levels, both in…”
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Lectins CGL and MTL, representatives of mytilectin family, exhibit different antiproliferative activity in Burkitt's lymphoma cells by Kuzmich, Alexandra S., Filshtein, Alina P., Likhatskaya, Galina N., Gorpenchenko, Tatiana Y., Chikalovets, Irina V., Mizgina, Tatyana O., Hua, Kuo‐Feng, Amsberg, Gunhild, Dyshlovoy, Sergey A., Chernikov, Oleg V.

“…Lectins are carbohydrate‐binding proteins, whose biological effects are exerted via binding to glycoconjugates expressed on the surface of cells. Exposure to…”
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