Search Results - "Cherian, M.George"

Zinc-metallothionein protects from DNA damage induced by radiation better than glutathione and copper- or cadmium-metallothioneins by Cai, Lu, Cherian, M.George

“…Protection of radiation-induced DNA damage by metallothionein (MT) has been documented, but there is no detailed information about its efficiency compared to…”
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Metallothionein in radiation exposure: its induction and protective role by Cai, Lu, Satoh, Masahiko, Tohyama, Chiharu, Cherian, M.George

“…Since its discovery about 40 years ago, there has been a wide interdisciplinary research interest in metallothionein (MT) on its physiological and…”
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Metallothioneins in Brain—The Role in Physiology and Pathology by Aschner, Michael, Cherian, M.George, Klaassen, Curtis D., Palmiter, Richard D., Erickson, Jay C., Bush, Ashley I.

“…A symposium on the role of brain metallothioneins (MTs) in physiology and pathology was held at the 1996 Annual Society of Toxicology Meeting in Anaheim,…”
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Roles of vitamin C in radiation-induced DNA damage in presence and absence of copper by Cai, Lu, Koropatnick, James, Cherian, M.George

“…Exposure to either ionizing radiation or certain transition metals results in generation of reactive oxygen species that induce DNA damage, mutation, and…”
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Astrocyte cultures from transgenic mice to study the role of metallothionein in cytotoxicity of tert-butyl hydroperoxide by Suzuki, Yutaka, Apostolova, Margarita D., Cherian, M.George

“…The cell viability, lipid peroxidation (LPO) and hydrogen peroxide (H 2O 2) generation were measured in cultured primary astrocytes, from metallothionein…”
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Metallothionein and Apoptosis during Differentiation of Myoblasts to Myotubes: Protection against Free Radical Toxicity by Apostolova, Margarita D., Ivanova, Iordanka A., Cherian, M.George

“…The changes in subcellular localization of metallothionein (MT) during differentiation were studied in two muscle cell lines, L6 and H9C2, myoblasts in order…”
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Metallothionein in human gingival amalgam tattoos by Lau, John C, Jackson-Boeters, Linda, Daley, Tom D, Wysocki, George P, Cherian, M.George

“…Amalgam tattoos occur when small particles of dental amalgam, composed largely of silver (Ag) and mercury (Hg), are inadvertently implanted into oral soft…”
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Role of placental metallothionein in maternal to fetal transfer of cadmium in genetically altered mice by Lau, John C, Joseph, Mariamma G, Cherian, M.George

“…The role of placental metallothionein (MT) as a barrier for maternal to fetal transfer of cadmium (Cd) was investigated using mice which overexpressed the MT-1…”
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Quantification of metallothioneins by a silver-saturation method by Scheuhammer, A M, Cherian, M G

“…The binding of Ag+ to metallothionein (MT) was investigated, and a Ag-saturation assay was developed for the measurement of MT in tissues. When samples of…”
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Regional brain distribution of metallothionein, zinc and copper in toxic milk mutant and transgenic mice by Ono, Shin-ichi, Koropatnick, D.James, Cherian, M.George

“…The regional distribution of metallothionein (MT), zinc and copper was measured in brains of transgenic MT-I overexpressor (MT-I*) mice, MT-I/MT-II gene…”
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The influence of nutritional deficiencies on gastrointestinal uptake of cadmium and cadmium-metallothionein in rats by Ohta, Hisayoshi, Cherian, M.George

“…The intestinal uptake and tissue distribution of cadmium (Cd) were studied in control rats and those deficient in zinc (Zn), iron (Fe) or cysteine (SH) using…”
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Comparison of metallothionein determination by polarographic and cadmium-saturation methods by Onosaka, S, Cherian, M G

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Exogenous metallothionein and renal toxicity of cadmium and mercury in rats by Chan, H M, Satoh, M, Zalups, R K, Cherian, M G

“…The relative tissue distribution and toxicity of cadmium (Cd) and mercury (Hg) in the liver and kidneys of rats when the metals are administered as either…”
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Immunohistochemical localization of metallothionein in the developing teeth of cadmium-injected rats by Tamura, Yukihiko, Wysocki, George P, Cherian, M.George

“…The ability of cadmium (Cd) to induce the synthesis of metallothionein (MT) in the developing teeth of the rat was investigated. Rats were given daily…”
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Changes in the intracellular accumulation and distribution of metallothionein in rat liver and kidney during postnatal development by Panemangalore, Myna, Banerjee, Diponkar, Onosaka, Satomi, Cherian, M.George

“…Metallothionein (MT) bound to zinc and copper was detected in high concentration in fetal and newborn rat livers by a cadmium saturation method. The levels of…”
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The induced synthesis of metallothionein in various tissues of rats in response to metals. II. Influence of zinc status and specific effect on pancreatic metallothionein by Onosaka, S, Cherian, M G

“…Metallothionein (MT) of various tissues contains bound zinc (Zn) and any change in Zn status can alter its synthesis and tissue deposition. The changes in MT…”
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Induction of metallothionein synthesis by zinc in cadmium pretreated rats by Suzuki, C A, Ohta, H, Albores, A, Koropatnick, J, Cherian, M G

“…The ability of zinc (Zn) salts to induce the synthesis of metallothionein (MT) in liver, kidney and pancreas of rats pretreated with cadmium (Cd) salts was…”
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Uptake of cadmium and metallothionein by rat everted intestinal sacs by Ohta, H, DeAngelis, M V, Cherian, M G

“…The gastrointestinal uptake and transport of cadmium (Cd) and the role of metallothionein (MT) were studied in everted sacs of rat intestine (ESRI). When ESRI…”
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Ascorbic acid and EDTA treatment of lead toxicity in rats by Goyer, R A, Cherian, M G

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Zinc- or cadmium-pre-induced metallothionein protects human central nervous system cells and astrocytes from radiation-induced apoptosis by Cai, Lu, Iskander, Sammy, Cherian, M.George, Hammond, Robert R.

“…We have shown the protection of human central nervous system (CNS) cultures by zinc (Zn) or cadmium (Cd)-pre-induced metallothionein (MT) synthesis from…”
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