Search Results - "Chepikova, Olga E."
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New Perspectives on the Role of Nuclear Proteases in Cell Death Pathways
Published in Biology (Basel, Switzerland) (31-05-2023)“…Multiple factors can trigger cell death via various pathways, and nuclear proteases have emerged as essential regulators of these processes. While certain…”
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Cellular Aging Characteristics and Their Association with Age-Related Disorders
Published in Antioxidants (22-01-2020)“…Different molecular signaling pathways, biological processes, and intercellular communication mechanisms control longevity and are affected during cellular…”
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Lysine oxidase exposes a dependency on the thioredoxin antioxidant pathway in triple-negative breast cancer cells
Published in Breast cancer research and treatment (01-10-2020)“…Purpose Transformed cells are vulnerable to depletion of certain amino acids. Lysine oxidase (LO) catalyzes the oxidative deamination of lysine, resulting in…”
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Evaluation of molecular mechanisms of riboflavin anti-COVID-19 action reveals anti-inflammatory efficacy rather than antiviral activity
Published in Biochimica et biophysica acta. General subjects (01-05-2024)“…Riboflavin (vitamin B2) is one of the most important water-soluble vitamins and a coenzyme involved in many biochemical processes. It has previously been shown…”
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Design and synthesis of atorvastatin derivatives with enhanced water solubility, hepatoselectivity and stability
Published in RSC medicinal chemistry (25-01-2023)“…Statins are effective 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMG-R) inhibitors, which are successfully used for cardiovascular disease treatment…”
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Synthesis, Characterization, and Preclinical Evaluation of a Small-Molecule Prostate-Specific Membrane Antigen-Targeted Monomethyl Auristatin E Conjugate
Published in Journal of medicinal chemistry (09-12-2021)“…Prostate cancer is the second most common type of cancer among men. Its main method of treatment is chemotherapy, which has a wide range of side effects. One…”
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