Search Results - "Cheong, Hae‐Kap"
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Template-Free Synthesis of a Molecular Solomon Link by Two-Component Self-Assembly
Published in Angewandte Chemie International Edition (05-02-2016)“…A molecular Solomon link was synthesized in high yield through the template‐free, coordination‐driven self‐assembly of a carbazole‐functionalized donor and a…”
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2
Magnetic control of self-assembly and disassembly in organic materials
Published in Nature communications (29-05-2023)“…Because organic molecules and materials are generally insensitive or weakly sensitive to magnetic fields, a certain means to enhance their magnetic…”
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3
Interaction of replication protein A with two acidic peptides from human Bloom syndrome protein
Published in FEBS letters (01-02-2018)“…Bloom syndrome protein (BLM) is one of five human RecQ helicases which maintain genomic stability. Interaction of BLM with replication protein A (RPA)…”
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4
Design of a binding scaffold based on variable lymphocyte receptors of jawless vertebrates by module engineering
Published in Proceedings of the National Academy of Sciences - PNAS (28-02-2012)“…Repeat proteins have recently been of great interest as potential alternatives to immunoglobulin antibodies due to their unique structural and biophysical…”
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5
Structural Studies on the Extracellular Domain of Sensor Histidine Kinase YycG from Staphylococcus aureus and Its Functional Implications
Published in Journal of molecular biology (31-07-2016)“…Bacterial two-component signal transduction systems are used to adapt to fluctuations in the environment. YycG, a key two-component histidine kinase in…”
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Interaction between human angiogenin and the p53 TAD2 domain and its implication for inhibitor discovery
Published in FEBS letters (01-12-2017)“…Interaction between angiogenin and the p53 TAD2 domain in cancer cells can inhibit the function of the p53 tumor suppressor and promote cell survival. Based on…”
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7
Nonenzymatic acetylation of ubiquitin Lys side chains is modulated by their neighboring residues
Published in The FEBS journal (01-04-2018)“…Nonenzymatic acetylation of Lys side chains (Lys‐SCs) by various in vivo reactive molecules has been suggested to play novel regulatory roles. Ubiquitin (UB)…”
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Crystal structure of the EnvZ periplasmic domain with CHAPS
Published in FEBS letters (01-05-2017)“…Bacteria sense and respond to osmolarity through the EnvZ‐OmpR two‐component system. The structure of the periplasmic sensor domain of EnvZ (EnvZ‐PD) is not…”
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Structural basis of the heterodimerization of the MST and RASSF SARAH domains in the Hippo signalling pathway
Published in Acta crystallographica. Section D, Biological crystallography. (01-07-2014)“…Despite recent progress in research on the Hippo signalling pathway, the structural information available in this area is extremely limited. Intriguingly, the…”
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10
Mechanism of Methylene Blue Inducing the Disulfide Bond Formation of Tubulin-Associated Unit Proteins
Published in JACS Au (22-07-2024)“…Methylene blue (MB) has recently completed a Phase-3 clinical trial as leuco-methylthioninium (LMT) bis(hydromethanesulfonate) for treating Alzheimer’s…”
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Structural Insight into Dimeric Interaction of the SARAH Domains from Mst1 and RASSF Family Proteins in the Apoptosis Pathway
Published in Proceedings of the National Academy of Sciences - PNAS (29-05-2007)“…In eukaryotic cells, apoptosis and cell cycle arrest by the Ras → RASSF → MST pathway are controlled by the interaction of SARAH (for Salvador/Rassf/Hippo)…”
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12
NMR elucidation of reduced B-Z transition activity of PKZ protein kinase at high NaCl concentration
Published in Biochemical and biophysical research communications (08-01-2017)“…A Z-DNA binding protein (ZBP)-containing protein kinase (PKZ) in fish species has an important role in the innate immune response. Previous structural studies…”
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13
NMR study of the antifreeze activities of active and inactive isoforms of a type III antifreeze protein
Published in FEBS letters (01-12-2016)“…The quaternary‐amino‐ethyl 1 (QAE1) isoforms of type III antifreeze proteins (AFPs) prevent the growth of ice crystals within organisms living in polar…”
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14
Dissecting the critical factors for thermodynamic stability of modular proteins using molecular modeling approach
Published in PloS one (21-05-2014)“…Repeat proteins have recently attracted much attention as alternative scaffolds to immunoglobulin antibodies due to their unique structural and biophysical…”
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15
Structure-based rational design of a Toll-like receptor 4 (TLR4) decoy receptor with high binding affinity for a target protein
Published in PloS one (17-02-2012)“…Repeat proteins are increasingly attracting much attention as alternative scaffolds to immunoglobulin antibodies due to their unique structural features…”
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16
Solution structure of the Zβ domain of human DNA-dependent activator of IFN-regulatory factors and its binding modes to B- and Z-DNAs
Published in Proceedings of the National Academy of Sciences - PNAS (26-04-2011)“…The DNA-dependent activator of IFN-regulatory factors (DAI), also known as DLM-1/ZBP1, initiates an innate immune response by binding to foreign DNAs in the…”
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Monothiol and dithiol glutaredoxin-1 from Clostridium oremlandii : identification of domain-swapped structures by NMR, X-ray crystallography and HDX mass spectrometry
Published in IUCrJ (01-11-2020)“…Protein dimerization or oligomerization resulting from swapping part of the protein between neighboring polypeptide chains is known to play a key role in the…”
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Mechanism of the pH-induced conformational change in the sensor domain of the DraK Histidine kinase via the E83, E105, and E107 residues
Published in PloS one (09-09-2014)“…The DraR/DraK two-component system was found to be involved in the differential regulation of antibiotic biosynthesis in a medium-dependent manner; however,…”
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Solution structure and Rpn1 interaction of the UBL domain of human RNA polymerase II C-terminal domain phosphatase
Published in PloS one (07-05-2013)“…The ubiquitin-like modifier (UBL) domain of ubiquitin-like domain proteins (UDPs) interacts specifically with subunits of the 26 S proteasome. A novel UDP,…”
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Structure of the Cdt1 C‐terminal domain: Conservation of the winged helix fold in replication licensing factors
Published in Protein science (01-11-2009)“…In eukaryotic replication licensing, Cdt1 plays a key role by recruiting the MCM2‐7 complex onto the origin of chromosome. The C‐terminal domain of mouse Cdt1…”
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