Search Results - "Cheong, Ed"

Current Evidence to Justify, and the Methodological Considerations for a Randomised Controlled Trial Testing the Hypothesis that Statins Prevent the Malignant Progression of Barrett's Oesophagus by David Thurtle, Leo Alexandre, Yoon K Loke, Ed Cheong, Andrew Hart

“…Barrett's oesophagus is the predominant risk factor for oesophageal adenocarcinoma, a cancer whose incidence is increasing and which has a poor prognosis. This…”
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Mutational signatures in esophageal adenocarcinoma define etiologically distinct subgroups with therapeutic relevance by Secrier, Maria, Li, Xiaodun, de Silva, Nadeera, Eldridge, Matthew D, Contino, Gianmarco, Bornschein, Jan, MacRae, Shona, Grehan, Nicola, O'Donovan, Maria, Miremadi, Ahmad, Yang, Tsun-Po, Bower, Lawrence, Chettouh, Hamza, Crawte, Jason, Galeano-Dalmau, Núria, Grabowska, Anna, Saunders, John, Underwood, Tim, Waddell, Nicola, Barbour, Andrew P, Nutzinger, Barbara, Achilleos, Achilleas, Edwards, Paul A W, Lynch, Andy G, Tavaré, Simon, Fitzgerald, Rebecca C

“…Rebecca Fitzgerald and colleagues report the whole-genome sequences of 129 esophageal adenocarcinomas, showing frequent copy number alterations and prevalent…”
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Whole-genome sequencing provides new insights into the clonal architecture of Barrett's esophagus and esophageal adenocarcinoma by Ross-Innes, Caryn S, Becq, Jennifer, Warren, Andrew, Cheetham, R Keira, Northen, Helen, O'Donovan, Maria, Malhotra, Shalini, di Pietro, Massimiliano, Ivakhno, Sergii, He, Miao, Weaver, Jamie M J, Lynch, Andy G, Kingsbury, Zoya, Ross, Mark, Humphray, Sean, Bentley, David, Fitzgerald, Rebecca C

“…Rebecca Fitzgerald and colleagues report whole-genome sequence analyses of 23 paired samples of Barrett's esophagus and esophageal adenocarcinoma. Their…”
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Ordering of mutations in preinvasive disease stages of esophageal carcinogenesis by Weaver, Jamie M J, Ross-Innes, Caryn S, Shannon, Nicholas, Lynch, Andy G, Forshew, Tim, Barbera, Mariagnese, Murtaza, Muhammed, Ong, Chin-Ann J, Lao-Sirieix, Pierre, Dunning, Mark J, Smith, Laura, Smith, Mike L, Anderson, Charlotte L, Carvalho, Benilton, O'Donovan, Maria, Underwood, Timothy J, May, Andrew P, Grehan, Nicola, Hardwick, Richard, Davies, Jim, Oloumi, Arusha, Aparicio, Sam, Caldas, Carlos, Eldridge, Matthew D, Edwards, Paul A W, Rosenfeld, Nitzan, Tavaré, Simon, Fitzgerald, Rebecca C

“…Rebecca Fitzgerald and colleagues used genome sequence analyses to study the progression from premalignant Barrett's esophagus to esophageal adenocarcinoma…”
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Machine learning to predict early recurrence after oesophageal cancer surgery by Rahman, S. A., Walker, R. C., Lloyd, M. A., Grace, B. L., van Boxel, G. I., Kingma, B. F., Ruurda, J. P., van Hillegersberg, R., Harris, S., Parsons, S., Mercer, S., Griffiths, E. A., O'Neill, J. R., Turkington, R., Fitzgerald, R. C., Underwood, T. J., Noorani, Ayesha, Elliott, Rachael Fels, Edwards, Paul A.W., Grehan, Nicola, Nutzinger, Barbara, Crawte, Jason, Chettouh, Hamza, Contino, Gianmarco, Li, Xiaodun, Gregson, Eleanor, Zeki, Sebastian, de la Rue, Rachel, Malhotra, Shalini, Tavaré, Simon, Lynch, Andy G., Smith, Mike L., Davies, Jim, Crichton, Charles, Carroll, Nick, Safranek, Peter, Hindmarsh, Andrew, Sujendran, Vijayendran, Hayes, Stephen J., Ang, Yeng, Preston, Shaun R., Oakes, Sarah, Bagwan, Izhar, Save, Vicki, Skipworth, Richard J.E., Hupp, Ted R., O'Neill, J. Robert, Tucker, Olga, Beggs, Andrew, Taniere, Philippe, Puig, Sonia, Underwood, Timothy J., Noble, Fergus, Byrne, James P., Kelly, Jamie J., Owsley, Jack, Barr, Hugh, Shepherd, Neil, Old, Oliver, Lagergren, Jesper, Gossage, James, Chang, Andrew Davies Fuju, Zylstra, Janine, Goh, Vicky, Ciccarelli, Francesca D., Sanders, Grant, Berrisford, Richard, Harden, Catherine, Bunting, David, Lewis, Mike, Cheong, Ed, Kumar, Bhaskar, Parsons, Simon L., Soomro, Irshad, Kaye, Philip, Saunders, John, Lovat, Laurence, Haidry, Rehan, Eneh, Victor, Igali, Laszlo, Scott, Michael, Sothi, Shamila, Suortamo, Sari, Lishman, Suzy, Hanna, George B., Peters, Christopher J., Grabowska, Anna

“…Background Early cancer recurrence after oesophagectomy is a common problem, with an incidence of 20–30 per cent despite the widespread use of neoadjuvant…”
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Understanding the malignant potential of gastric metaplasia of the oesophagus and its relevance to Barrett's oesophagus surveillance: individual-level data analysis by Black, Emily L, Ococks, Emma, Devonshire, Ginny, Ng, Alvin Wei Tian, O'Donovan, Maria, Malhotra, Shalini, Tripathi, Monika, Miremadi, Ahmad, Freeman, Adam, Coles, Hannah, Fitzgerald, Rebecca C

“…Whether gastric metaplasia (GM) of the oesophagus should be considered as Barrett's oesophagus (BO) is controversial. Given concern intestinal metaplasia (IM)…”
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Disentangling oncogenic amplicons in esophageal adenocarcinoma by Ng, Alvin Wei Tian, McClurg, Dylan Peter, Wesley, Ben, Zamani, Shahriar A., Black, Emily, Miremadi, Ahmad, Giger, Olivier, Hoopen, Rogier ten, Devonshire, Ginny, Redmond, Aisling M., Grehan, Nicola, Jammula, Sriganesh, Blasko, Adrienn, Li, Xiaodun, Aparicio, Samuel, Tavaré, Simon, Nowicki-Osuch, Karol, Fitzgerald, Rebecca C.

“…Esophageal adenocarcinoma is a prominent example of cancer characterized by frequent amplifications in oncogenes. However, the mechanisms leading to amplicons…”
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Author Correction: Disentangling oncogenic amplicons in esophageal adenocarcinoma by Ng, Alvin Wei Tian, McClurg, Dylan Peter, Wesley, Ben, Zamani, Shahriar A., Black, Emily, Miremadi, Ahmad, Giger, Olivier, Hoopen, Rogier ten, Devonshire, Ginny, Redmond, Aisling M., Grehan, Nicola, Jammula, Sriganesh, Blasko, Adrienn, Li, Xiaodun, Aparicio, Samuel, Tavaré, Simon, Nowicki-Osuch, Karol, Fitzgerald, Rebecca C.

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Multicentre validation of CT grey-level co-occurrence matrix features for overall survival in primary oesophageal adenocarcinoma by O’Shea, Robert, Withey, Samuel J., Owczarczyk, Kasia, Rookyard, Christopher, Gossage, James, Godfrey, Edmund, Jobling, Craig, Parsons, Simon L., Skipworth, Richard J. E., Goh, Vicky

“…Background Personalising management of primary oesophageal adenocarcinoma requires better risk stratification. Lack of independent validation of proposed…”
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Multi-Omic Analysis of Esophageal Adenocarcinoma Uncovers Candidate Therapeutic Targets and Cancer-Selective Posttranscriptional Regulation by O'Neill, J. Robert, Yébenes Mayordomo, Marcos, Mitulović, Goran, Al Shboul, Sofian, Bedran, Georges, Faktor, Jakub, Hernychova, Lenka, Uhrik, Lukas, Gómez-Herranz, Maria, Kocikowski, Mikołaj, Save, Vicki, Vojtěšek, Bořivoj, Arends, Mark J., Fitzgerald, Rebecca C., Edwards, Paul A.W., Grehan, Nicola, Nutzinger, Barbara, Loreno, Christine, Redmond, Aisling M., Abbas, Sujath, Freeman, Adam, Smyth, Elizabeth C., O'Donovan, Maria, Miremadi, Ahmad, Malhotra, Shalini, Tripathi, Monika, Cheah, Calvin, Coles, Hannah, Millington, Curtis, Devonshire, Ginny, Eldridge, Matthew, Secrier, Maria, Jammula, Sriganesh, Davies, Jim, Crichton, Charles, Carroll, Nick, Hardwick, Richard H., Safranek, Peter, Hindmarsh, Andrew, Sujendran, Vijayendran, Hayes, Stephen J., Ang, Yeng, Sharrocks, Andrew, Preston, Shaun R., Bagwan, Izhar, Save, Vicki, Skipworth, Richard J.E., Hupp, Ted R., O'Neill, J Robert, Tucker, Olga, Beggs, Andrew, Taniere, Philippe, Puig, Sonia, Contino, Gianmarco, Underwood, Timothy J., Walker, Robert C., Grace, Ben L., Lagergren, Jesper, Gossage, James, Davies, Andrew, Chang, Fuju, Mahadeva, Ula, Goh, Vicky, Ciccarelli, Francesca D., Sanders, Grant, Berrisford, Richard, Chan, David, Cheong, Ed, Kumar, Bhaskar, Sreedharan, L., Parsons, Simon L., Soomro, Irshad, Kaye, Philip, Saunders, John, Lovat, Laurence, Haidry, Rehan, Scott, Michael, Sothi, Sharmila, Lishman, Suzy, Hanna, George B., Peters, Christopher J., Moorthy, Krishna, Grabowska, Anna, Turkington, Richard, McManus, Damian, Coleman, Helen, Petty, Russell D., Bartlet, Freddie, Hupp, Ted, Alfaro, Javier Antonio

“…Efforts to address the poor prognosis associated with esophageal adenocarcinoma (EAC) have been hampered by a lack of biomarkers to identify early disease and…”
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A decade of the Oesophageal Cancer Clinical and Molecular Stratification Consortium by Peters, C. J., Ang, Y., Ciccarelli, F. D., Coles, H., Coleman, H. G., Contino, G., Crosby, T., Devonshire, G., Eldridge, M., Freeman, A., Grehan, N., McCord, M., Nutzinger, B., Zamani, S., Parsons, S. L., Petty, R., Sharrocks, A. D., Skipworth, R. J. E., Smyth, E. C., Soomro, I., Underwood, T. J., Fitzgerald, R. C.

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Authentication and characterisation of a new oesophageal adenocarcinoma cell line: MFD-1 by Garcia, Edwin, Hayden, Annette, Birts, Charles, Britton, Edward, Cowie, Andrew, Pickard, Karen, Mellone, Massimiliano, Choh, Clarisa, Derouet, Mathieu, Duriez, Patrick, Noble, Fergus, White, Michael J., Primrose, John N., Strefford, Jonathan C., Rose-Zerilli, Matthew, Thomas, Gareth J., Ang, Yeng, Sharrocks, Andrew D., Fitzgerald, Rebecca C., Underwood, Timothy J.

“…New biological tools are required to understand the functional significance of genetic events revealed by whole genome sequencing (WGS) studies in oesophageal…”
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Authentication and characterisation of a new oesophageal adenocarcinoma cell line: MFD-1 (vol 6, 32417, 2016) by Garcia, E, Hayden, A, Birts, C, Britton, E, Rogerson, C, Bleaney, CW, Cowie, A, Pickard, K, Mellone, M, Choh, C

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Rearrangement processes and structural variations show evidence of selection in oesophageal adenocarcinomas by Ng, Alvin Wei Tian, Contino, Gianmarco, Killcoyne, Sarah, Devonshire, Ginny, Hsu, Ray, Abbas, Sujath, Su, Jing, Redmond, Aisling M., Weaver, Jamie M. J., Eldridge, Matthew D., Tavaré, Simon, Edwards, Paul A. W., Fitzgerald, Rebecca C.

“…Oesophageal adenocarcinoma (OAC) provides an ideal case study to characterize large-scale rearrangements. Using whole genome short-read sequencing of 383…”
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The transcriptional landscape of endogenous retroelements delineates esophageal adenocarcinoma subtypes by Kazachenka, Anastasiya, Loong, Jane Hc, Attig, Jan, Young, George R, Ganguli, Piyali, Devonshire, Ginny, Grehan, Nicola, Ciccarelli, Francesca D, Fitzgerald, Rebecca C, Kassiotis, George

“…Abstract Most cancer types exhibit aberrant transcriptional activity, including derepression of retrotransposable elements (RTEs). However, the degree,…”
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COVID-19, Education, and Literacy in Malaysia: Social Contexts of Teaching and Learning. COVID-19 in Asia by Pandian, Ambigapathy, Ed, Kaur, Surinderpal, Ed, Cheong, Huey Fen, Ed

“…Part of a mini series of Focus books on COVID-19 in Malaysia, the chapters in this book address the pandemic's impacts on education and literacy. Covering a…”
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