Search Results - "Chenwi, Collins"
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HIV-1 residual risk and pre-treatment drug resistance among blood donors: A sentinel surveillance from Gabon
Published in PloS one (03-09-2024)“…Surveillance of HIV-1 pre-treatment drug resistance (PDR) is essential for ensuring the success of first-line antiretroviral therapy (ART). Beside…”
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Correlation between the immuno-virological response and the nutritional profile of treatment-experienced HIV-infected patients in the East region of Cameroon
Published in PloS one (13-05-2021)“…HIV management remains concerning and even more challenging in the frame of comorbidities like malnutrition that favors disease progression and mortality in…”
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HIV-1 genotypic profiling ensures effective response to third-line antiretroviral therapy in Cameroon
Published in Medicine (Baltimore) (02-06-2023)“…In order to limit the emergence of human immunodeficiency virus (HIV) drug resistance in a context of limited antiretroviral options, we sought to evaluate the…”
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HIV-1 subtype diversity and immuno-virological outcomes among adolescents failing antiretroviral therapy in Cameroon: A cohort study
Published in PloS one (25-10-2023)“…Objective We sought to evaluate the variability of HIV-1 and its effect on immuno-virological response among adolescents living with perinatally acquired HIV…”
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Determinants of immunovirological response among children and adolescents living with HIV-1 in the Central Region of Cameroon
Published in Tropical medicine and infectious disease (01-02-2024)“…About 90% of new HIV-1 infections in children occur in sub-Saharan Africa, where treatment monitoring remains suboptimal. We sought to ascertain factors…”
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Determinants of survival of adolescents receiving antiretroviral therapy in the Centre Region of Cameroon: a multi-centered cohort-analysis
Published in AIDS research and therapy (15-12-2023)“…In spite of the global decreasing mortality associated with HIV, adolescents living with HIV (ADLHIV) in sub-Saharan Africa still experience about 50%…”
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Laboratory Based Surveillance of HIV-1 Acquired Drug Resistance in Cameroon: Implications for Use of Tenofovir-Lamivudine-Dolutegravir (TLD) as Second- or Third-Line Regimens
Published in Viruses (01-08-2023)“…Increased HIV drug resistance (HIVDR) with antiretroviral therapy (ART) rollout may jeopardize therapeutic options, especially in this era of transition to…”
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Pre-Treatment HIV Drug Resistance and Genetic Diversity in Cameroon: Implications for First-Line Regimens
Published in Viruses (28-06-2023)“…The efficacy of first-line antiretroviral therapy (ART) may be hampered by the presence of HIV drug resistance (HIVDR). We described HIV-1 pre-treatment drug…”
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Archiving of mutations in HIV‐1 cellular reservoirs among vertically infected adolescents is contingent with clinical stages and plasma viral load: Evidence from the EDCTP‐READY study
Published in HIV medicine (01-07-2022)“…Introduction Globally, HIV‐related adolescent deaths have increased about 50%, especially for those who are vertically infected. This could be driven by…”
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Evaluation of hepatic fibrosis in HIV/HCV co-infected individuals in Yaoundé, Cameroon: usefulness of APRI score in resource-constrained settings
Published in BMC infectious diseases (15-10-2020)“…Abstract Background HIV infection exacerbates the prognosis of HCV infection, with a faster progression of hepatitis. Hepatic fibrosis is the major disruption…”
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Pre-existing immunity to SARS-CoV-2 before the COVID-19 pandemic era in Cameroon: A comparative analysis according to HIV-status
Published in Frontiers in immunology (08-03-2023)“…The lower burden of COVID-19 in tropical settings may be due to preexisting cross-immunity, which might vary according to geographical locations and potential…”
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Evaluation of archived drug resistance mutations in HIV‐1 DNA among vertically infected adolescents under antiretroviral treatment in Cameroon: Findings during the COVID‐19 pandemic
Published in HIV medicine (01-06-2023)“…Background With the success of antiretroviral therapy (ART), children born with HIV are more likely to reach adolescence. However, frequent non‐adherence to…”
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Human immunodeficiency virus is a driven factor of human papilloma virus among women: evidence from a cross-sectional analysis in Yaoundé, Cameroon
Published in Virology journal (19-05-2020)“…Human papillomavirus (HPV) is the leading cause of cervical cancers, causing 270.000 deaths annually worldwide of which 85% occur in developing countries with…”
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PA-351 HIV-1 genotypic susceptibility to second generation non-nucleoside reverse transcriptase inhibitors among patients failing antiretroviral therapy in Cameroon: implication for the long-acting therapies in Africa
Published in BMJ global health (17-12-2023)“…BackgroundLong-acting therapies combining second generation non-nucleoside reverse transcriptase inhibitors (2Gen-NNRTI) with integrase inhibitor (INSTIs) such…”
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Diagnostic performance of a colorimetric RT -LAMP for the identification of SARS-CoV-2: A multicenter prospective clinical evaluation in sub-Saharan Africa
Published in EClinicalMedicine (01-10-2021)“…Management and control of the COVID-19 pandemic caused by the severe acute respiratory syndrome coronavirus SARS-CoV-2 is critically dependent on quick and…”
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Variability of High-Risk Human Papillomavirus and Associated Factors among Women in Sub-Saharan Africa: A Systematic Review and Meta-Analysis
Published in Pathogens (Basel) (01-08-2023)“…Background: Sub-Saharan Africa (SSA) carries the highest burden of high-risk human papillomavirus (HR-HPV) in the world, driven by, and together with, HIV…”
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PA-402 Predictors of archived HIV-1 drug resistance mutations in cellular reservoirs of virally suppressed adolescents: the EDCTP READY-study TMA2025-CDF1027
Published in BMJ global health (17-12-2023)“…BackgroundEven though 92% of people receiving antiretroviral treatment (ART) have achieved viral suppression (VS) globally, adolescents with perinatal…”
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Epidemiological, virological and clinical features of SARS-CoV-2 among individuals during the first wave in Cameroon: Baseline analysis for the EDCTP PERFECT-Study RIA2020EF-3000
Published in Journal of public health in Africa (24-05-2022)“…In Cameroon, COVID-19 infection spread rapidly and nationwide, with up to 721 deaths reported. To the best of our knowledge, no study reported the on-theground…”
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SARS-CoV-2 genomic surveillance and reliability of PCR single point mutation assay (SNPsig® SARS-CoV-2 EscapePLEX CE) for the rapid detection of variants of concern in Cameroon
Published in Heliyon (15-04-2024)“…Surveillance of SARS-CoV-2 variants of concern (VOCs) and lineages is crucial for decision-making. Our objective was to study the SARS-CoV-2 clade dynamics…”
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Genotypic resistance testing improves antiretroviral treatment outcomes in a cohort of adolescents in Cameroon: Implications in the dolutegravir‑era
Published in Journal of public health in Africa (01-10-2023)“…Poor internet infrastructure limits the use of computer-based nursing process forms in rural areas. This study aimed to configure a computer‑based nursing…”
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