Search Results - "Chensue, Stephen W."

Seroprevalence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection among Veterans Affairs healthcare system employees suggests higher risk of infection when exposed to SARS-CoV-2 outside the work environment by Dimcheff, Derek E, Schildhouse, Richard J, Hausman, Mark S, Vincent, Brenda M, Markovitz, Erica, Chensue, Stephen W, Deng, Jane, McLeod, Melissa, Hagan, Danielle, Russell, Jon, Bradley, Suzanne F

“…The seroprevalence of severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) IgG antibody was evaluated among employees of a Veterans Affairs healthcare…”
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Human CD56+ cytotoxic lung lymphocytes kill autologous lung cells in chronic obstructive pulmonary disease by Freeman, Christine M, Stolberg, Valerie R, Crudgington, Sean, Martinez, Fernando J, Han, MeiLan K, Chensue, Stephen W, Arenberg, Douglas A, Meldrum, Catherine A, McCloskey, Lisa, Curtis, Jeffrey L

“…CD56+ natural killer (NK) and CD56+ T cells, from sputum or bronchoalveolar lavage of subjects with chronic obstructive pulmonary disease (COPD) are more…”
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TLR9 regulates the mycobacteria-elicited pulmonary granulomatous immune response in mice through DC-derived Notch ligand delta-like 4 by Ito, Toshihiro, Schaller, Matthew, Hogaboam, Cory M, Standiford, Theodore J, Sandor, Matyas, Lukacs, Nicholas W, Chensue, Stephen W, Kunkel, Steven L

“…TLR9 activation is important for the maintenance of mycobacteria-elicited pulmonary granulomatous responses, hallmarks of protective immune responses following…”
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SARS-CoV-2 Anti-Spike IgG Antibody and ACE2 Receptor Binding Inhibition Levels among Breakthrough Stage Veteran Patients by Chensue, Stephen W, Siler, Andrew F, Kim, Paul S, Dimcheff, Derek E, Daghfal, David J, Prostko, John, Frias, Edwin, Linder, Kathleen A, Schildhouse, Richard J

“…SARS-CoV-2 mRNA vaccines have been critical to curbing pandemic COVID-19; however, a major shortcoming has been the inability to assess levels of protection…”
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Lung CD8+ T cells in COPD have increased expression of bacterial TLRs by Freeman, Christine M, Martinez, Fernando J, Han, Meilan K, Washko, Jr, George R, McCubbrey, Alexandra L, Chensue, Stephen W, Arenberg, Douglas A, Meldrum, Catherine A, McCloskey, Lisa, Curtis, Jeffrey L

“…Toll-like receptors (TLRs) on T cells can modulate their responses, however, the extent and significance of TLR expression by lung T cells, NK cells, or NKT…”
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Basal gene expression by lung CD4+ T cells in chronic obstructive pulmonary disease identifies independent molecular correlates of airflow obstruction and emphysema extent by Freeman, Christine M, McCubbrey, Alexandra L, Crudgington, Sean, Nelson, Joshua, Martinez, Fernando J, Han, MeiLan K, Washko, Jr, George R, Chensue, Stephen W, Arenberg, Douglas A, Meldrum, Catherine A, McCloskey, Lisa, Curtis, Jeffrey L

“…Lung CD4+ T cells accumulate as chronic obstructive pulmonary disease (COPD) progresses, but their role in pathogenesis remains controversial. To address this…”
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Disruption of Early Tumor Necrosis Factor Alpha Signaling Prevents Classical Activation of Dendritic Cells in Lung-Associated Lymph Nodes and Development of Protective Immunity against Cryptococcal Infection by Xu, Jintao, Eastman, Alison J, Flaczyk, Adam, Neal, Lori M, Zhao, Guolei, Carolan, Jacob, Malachowski, Antoni N, Stolberg, Valerie R, Yosri, Mohammed, Chensue, Stephen W, Curtis, Jeffrey L, Osterholzer, John J, Olszewski, Michal A

“…Anti-tumor necrosis factor alpha (anti-TNF-α) therapies have been increasingly used to treat inflammatory diseases and are associated with increased risk of…”
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TLR9 activation is a key event for the maintenance of a mycobacterial antigen-elicited pulmonary granulomatous response by Ito, Toshihiro, Schaller, Matthew, Hogaboam, Cory M, Standiford, Theodore J, Chensue, Stephen W, Kunkel, Steven L

“…Type 1 (Th1) granulomas can be studied in mice sensitized with mycobacterium antigens followed by challenge of agarose beads covalently coupled to purified…”
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Smoking decreases the response of human lung macrophages to double-stranded RNA by reducing TLR3 expression by Todt, Jill C, Freeman, Christine M, Brown, Jeanette P, Sonstein, Joanne, Ames, Theresa M, McCubbrey, Alexandra L, Martinez, Fernando J, Chensue, Stephen W, Beck, James M, Curtis, Jeffrey L

“…Cigarette smoking is associated with increased frequency and duration of viral respiratory infections, but the underlying mechanisms are incompletely defined…”
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Erratum for Xu et al., "Disruption of Early Tumor Necrosis Factor Alpha Signaling Prevents Classical Activation of Dendritic Cells in Lung-Associated Lymph Nodes and Development of Protective Immunity against Cryptococcal Infection" by Xu, Jintao, Eastman, Alison J, Flaczyk, Adam, Neal, Lori M, Zhao, Guolei, Carolan, Jacob, Malachowski, Antoni N, Stolberg, Valerie R, Yosri, Mohammed, Chensue, Stephen W, Curtis, Jeffrey L, Osterholzer, John J, Olszewski, Michal A

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Dysregulated cytokine expression by CD4+ T cells from post-septic mice modulates both Th1 and Th2-mediated granulomatous lung inflammation by Carson, 4th, William F, Ito, Toshihiro, Schaller, Matthew, Cavassani, Karen A, Chensue, Stephen W, Kunkel, Steven L

“…Previous epidemiological studies in humans and experimental studies in animals indicate that survivors of severe sepsis exhibit deficiencies in the activation…”
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Molecular Machinations: Chemokine Signals in Host-Pathogen Interactions by CHENSUE, Stephen W

“…Classifications Services CMR Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Effect of monoclonal antibody therapy on the endogenous SARS-CoV-2 antibody response by Kim, Paul S., Dimcheff, Derek E., Siler, Andrew, Schildhouse, Richard J., Chensue, Stephen W.

“…Monoclonal antibody treatment of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection has been widely implemented. Effects of treatment on…”
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Toll-like Receptor 9 Activation Is a Key Mechanism for the Maintenance of Chronic Lung Inflammation by Ito, Toshihiro, Schaller, Matthew, Raymond, Tracy, Joshi, Amrita D, Coelho, Ana L, Frantz, Fabiani G, Carson, William F., IV, Hogaboam, Cory M, Lukacs, Nicholas W, Standiford, Theodore J, Phan, Sem H, Chensue, Stephen W, Kunkel, Steven L

“…Accumulating evidence supports the hypothesis that the continuous host response to a persistent challenge can polarize the cytokine environment toward a Th2…”
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Cutting edge: Central memory CD8 T cells in aged mice are virtual memory cells by Chiu, Bo-Chin, Martin, Brian E, Stolberg, Valerie R, Chensue, Stephen W

“…The number of memory phenotype CD8 T cells increases dramatically with aging in both humans and mice. However, the mechanism for this is unknown. The…”
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Delta-like 4 differentially regulates murine CD4 T cell expansion via BMI1 by Schaller, Matthew A, Logue, Hannah, Mukherjee, Sumanta, Lindell, Dennis M, Coelho, Ana Lucia, Lincoln, Pamela, Carson, 4th, William F, Ito, Toshihiro, Cavassani, Karen A, Chensue, Stephen W, Hogaboam, Cory M, Lukacs, Nicholas W, Kunkel, Steven L

“…Studies have shown that Notch is essential for the maintenance of a T cell Th2 phenotype in vivo. It has also been shown that Notch ligands have diverse…”
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Chemokine Expression Dynamics in Mycobacterial (Type-1) and Schistosomal (Type-2) Antigen-Elicited Pulmonary Granuloma Formation by Qiu, Boqin, Frait, Kirsten A., Reich, Filip, Komuniecki, Eric, Chensue, Stephen W.

“…Transcript expression of 24 chemokines (CKs) was examined throughout 8 days in mouse lungs with type-1 (Th1) or type-2 (Th2) cytokine-mediated granulomas…”
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Malaria and Pregnancy: Placental Cytokine Expression and Its Relationship to Intrauterine Growth Retardation by Moormann, Ann M., Sullivan, Amy D., Rochford, Rosemary A., Chensue, Stephen W., Bock, Paul J., Nyirenda, Thomas, Meshnick, Steven R.

“…Malaria infections during pregnancy can lead to the delivery of low-birth-weight infants. In this study, cytokine mRNA was measured in placentas from 23…”
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A Novel Model of Demyelinating Encephalomyelitis Induced by Monocytes and Dendritic Cells by Furtado, Glaucia C, Pina, Beatrice, Tacke, Frank, Gaupp, Stefanie, van Rooijen, Nico, Moran, Thomas M, Randolph, Gwendalyn J, Ransohoff, Richard M, Chensue, Stephen W, Raine, Cedric S, Lira, Sergio A

“…Local inflammation may be a precipitating event in autoimmune processes. In this study, we demonstrate that regulated influx of monocytes and dendritic cells…”
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EAE mediated by a non-IFN-γ/non-IL-17 pathway by Kroenke, Mark A, Chensue, Stephen W, Segal, Benjamin M

“…Previous studies have shown that EAE can be elicited by the adoptive transfer of either IFN-γ-producing (Th1) or IL-17-producing (Th17) myelin-specific CD4⁺…”
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