Search Results - "Chenik, Mehdi"

Polylactide Nanoparticles as a Biodegradable Vaccine Adjuvant: A Study on Safety, Protective Immunity and Efficacy against Human Leishmaniasis Caused by Leishmania Major by Ayari-Riabi, Sana, Ben Khalaf, Noureddine, Bouhaouala-Zahar, Balkiss, Verrier, Bernard, Trimaille, Thomas, Benlasfar, Zakaria, Chenik, Mehdi, Elayeb, Mohamed

“…Leishmaniasis is the 3rd most challenging vector-borne disease after malaria and lymphatic filariasis. Currently, no vaccine candidate is approved or marketed…”
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Immunomodulatory Effects of Four Leishmania infantum Potentially Excreted/Secreted Proteins on Human Dendritic Cells Differentiation and Maturation by Markikou-Ouni, Wafa, Drini, Sima, Bahi-Jaber, Narges, Chenik, Mehdi, Meddeb-Garnaoui, Amel

“…Leishmania parasites and some molecules they secrete are known to modulate innate immune responses through effects on dendritic cells (DCs) and macrophages…”
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Prediction of T Cell Epitopes from Leishmania major Potentially Excreted/Secreted Proteins Inducing Granzyme B Production by Naouar, Ikbel, Boussoffara, Thouraya, Chenik, Mehdi, Gritli, Sami, Ben Ahmed, Melika, Belhadj Hmida, Nabil, Bahi-Jaber, Narges, Bardi, Rafika, Gorgi, Yousr, Ben Salah, Afif, Louzir, Hechmi

“…Leishmania-specific cytotoxic T cell response is part of the acquired immune response developed against the parasite and contributes to resistance to…”
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In vitro evaluation of a soluble Leishmania promastigote surface antigen as a potential vaccine candidate against human leishmaniasis by Chamakh-Ayari, Rym, Bras-Gonçalves, Rachel, Bahi-Jaber, Narges, Petitdidier, Elodie, Markikou-Ouni, Wafa, Aoun, Karim, Moreno, Javier, Carrillo, Eugenia, Salotra, Poonam, Kaushal, Himanshu, Negi, Narender Singh, Arevalo, Jorge, Falconi-Agapito, Francesca, Privat, Angela, Cruz, Maria, Pagniez, Julie, Papierok, Gérard-Marie, Rhouma, Faten Bel Haj, Torres, Pilar, Lemesre, Jean-Loup, Chenik, Mehdi, Meddeb-Garnaoui, Amel

“…PSA (Promastigote Surface Antigen) belongs to a family of membrane-bound and secreted proteins present in several Leishmania (L.) species. PSA is recognized by…”
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Leishmania major large RAB GTPase is highly immunogenic in individuals immune to cutaneous and visceral leishmaniasis by Chamakh-Ayari, Rym, Chenik, Mehdi, Chakroun, Ahmed Sahbi, Bahi-Jaber, Narges, Aoun, Karim, Meddeb-Garnaoui, Amel

“…We previously identified a Leishmania (L.) major large RAB GTPase (LmlRAB), a new atypical RAB GTPase protein. It is highly conserved in Leishmania species…”
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Comparative Evaluation of Two Vaccine Candidates against Experimental Leishmaniasis Due to Leishmania major Infection in Four Inbred Mouse Strains by Benhnini, Fouad, Chenik, Mehdi, Laouini, Dhafer, Louzir, Hechmi, Cazenave, Pierre André, Dellagi, Koussay

“…Classifications Services CVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Comparative evaluation of ELISAs based on ten recombinant or purified Leishmania antigens for the serodiagnosis of Mediterranean visceral leishmaniasis by Maalej, Ibtissem Abdmouleh, Chenik, Mehdi, Louzir, Hechmi, Ben Salah, Afif, Bahloul, Chokri, Amri, Fethi, Dellagi, Koussay

“…This study compared a panel of 10 enzyme-linked immunosorbent assays (ELISAs) for the serodiagnosis of Mediterranean visceral leishmaniasis (MVL). The ELISAs…”
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Cellular and Humoral Responses to Leishmania major Virulence Factors in Healed Cutaneous Leishmaniasis and Mediterranean Visceral Leishmaniasis Patients by Lakhal-Naouar, Ines, Boussoffara, Thouraya, Meddeb-Garnaoui, Amel, Achour-Chenik, Yosser Ben, Louzir, Hechmi, Chenik, Mehdi

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An approach for interlaboratory comparison of conventional and real-time PCR assays for diagnosis of human leishmaniasis by Cruz, Israel, Millet, Aurélie, Carrillo, Eugenia, Chenik, Mehdi, Salotra, Poonam, Verma, Sandeep, Veland, Nicolás, Jara, Marlene, Adaui, Vanessa, Castrillón, Carlos, Arévalo, Jorge, Moreno, Javier, Cañavate, Carmen

“…•A user friendly protocol for interlaboratory comparison of PCR methods is proposed.•Participants from endemic areas in four continents evaluated different PCR…”
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Leishmania major protein disulfide isomerase as a drug target: Enzymatic and functional characterization by Ben Khalaf, Noureddine, De Muylder, Géraldine, Louzir, Hechmi, McKerrow, James, Chenik, Mehdi

“…Leishmaniasis is a major health problem worldwide and tools available for their control are limited. Effective vaccines are still lacking, drugs are toxic and…”
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Leishmania major protein disulfide isomerase as a drug target by Khalaf, Noureddine Ben, Muylder, Geraldine De, Louzir, Hechmi, McKerrow, James, Chenik, Mehdi

“…Leishmaniasis is a major health problem worldwide and tools available for their control are limited. Effective vaccines are still lacking, drugs are toxic and…”
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Immunomodulatory Effects of Four Leishmania infantum Potentially Excreted/Secreted Proteins on Human Dendritic Cells Differentiation and Maturation: e0143063 by Markikou-Ouni, Wafa, Drini, Sima, Bahi-Jaber, Narges, Chenik, Mehdi, Meddeb-Garnaoui, Amel

“…Leishmania parasites and some molecules they secrete are known to modulate innate immune responses through effects on dendritic cells (DCs) and macrophages…”
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A high-throughput turbidometric assay for screening inhibitors of Leishmania major protein disulfide isomerase by Ben Khalaf, Noureddine, De Muylder, Géraldine, Ratnam, Joseline, Kean-Hooi Ang, Kenny, Arkin, Michelle, McKerrow, James, Chenik, Mehdi

“…The use of a high-throughput technique to perform a pilot screen for Leishmania major protein disulfide isomerase (LmPDI) inhibitors identification is…”
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Identification and characterization of a new Leishmania major specific 3′nucleotidase/nuclease protein by Lakhal-Naouar, Inès, Achour-Chenik, Yosser Ben, Boublik, Yvan, Meddeb, Mounira, Aamouri, Ahlem, Fattoum, Abdellatif, Louzir, Hechmi, Chenik, Mehdi

“…We report the characterization of a new Leishmania major gene, lmaj3′nt/nu, encoding a 382 amino acids protein, Lmaj3′NT/NU, that belongs to the…”
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Molecular cloning of disintegrins from Cerastes vipera and Macrovipera lebetina transmediterranea venom gland cDNA libraries: insight into the evolution of the snake venom integrin-inhibition system by Sanz, Libia, Bazaa, Amine, Marrakchi, Naziha, Pérez, Alicia, Chenik, Mehdi, Bel Lasfer, Zakaria, El Ayeb, Mohamed, Calvete, Juan J

“…We report the cloning and sequence analysis of Cerastes vipera and Macrovipera lebetina transmediterranea cDNAs coding for short non-RGD (Arg-Gly-Asp)…”
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Prediction of T Cell Epitopes from Leishmania major Potentially Excreted/Secreted Proteins Inducing Granzyme B Production: e0147076 by Naouar, Ikbel, Boussoffara, Thouraya, Chenik, Mehdi, Gritli, Sami, Ahmed, Melika Ben, Hmida, Nabil Belhadj, Bahi-Jaber, Narges, Bardi, Rafika, Gorgi, Yousr, Salah, Afif Ben

“…Leishmania-specific cytotoxic T cell response is part of the acquired immune response developed against the parasite and contributes to resistance to…”
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Selection of endogenous reference genes for gene expression analysis in Leishmania major developmental stages by Ouakad, Meriam, Bahi-Jaber, Narges, Chenik, Mehdi, Dellagi, Koussay, Louzir, Hechmi

“…At the era of post-genomics, gene expression analysis constitutes an important step for understanding the biological functions of genes. For this, reverse…”
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Identification and characterization of a new Leishmania major specific 3'nucleotidase/nuclease protein by Lakhal-Naouar, Inès, Ben Achour-Chenik, Yosser, Boublik, Yvan, Meddeb, Mounira, Aamouri, Ahlem, Fattoum, Abdellatif, Louzir, Hechmi, Chenik, Mehdi

“…We report the characterization of a new Leishmania major gene, lmaj3'nt/nu, encoding a 382 amino acids protein, Lmaj3'NT/NU, that belongs to the…”
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Identification of a new developmentally regulated Leishmania major large RAB GTPase by Chenik, Mehdi, Chaabouni, Noura, Achour-Chenik, Yosser Ben, Ouakad, Meriem, Lakhal-Naouar, Inès, Louzir, Hechmi, Dellagi, Koussay

“…Here, we describe for the first time a Leishmania specific gene encoding a large 610 amino-acid RAB GTPase (LmLRAB). LmLRAB displays high homologies with the…”
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Gene expression analysis of wild Leishmania major isolates : identification of genes preferentially expressed in amastigotes by OUAKAD, Meriem, CHENIK, Mehdi, ACHOUR-CHENIK, Yosser Ben, LOUZIR, Hechmi, DELLAGI, Koussay

“…Trying to identify virulence genes of wild Leishmania (L.) major parasites, the species responsible for zoonotic cutaneous leishmaniasis, we compared, using…”
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