Search Results - "Cheng-Yan Kao"
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Gene expression-based chemical genomics identifies potential therapeutic drugs in hepatocellular carcinoma
Published in PloS one (07-11-2011)“…Hepatocellular carcinoma (HCC) is an aggressive tumor with a poor prognosis. Currently, only sorafenib is approved by the FDA for advanced HCC treatment;…”
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Prevalence of intestinal parasitic infections among school children in capital areas of the Democratic Republic of São Tomé and Príncipe, West Africa
Published in African health sciences (01-09-2016)“…Background: Although the Democratic Republic of Sao Tome and Principe (DRSTP) has undertaken school children-based deworming programs against intestinal…”
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Construction and analysis of the protein-protein interaction networks for schizophrenia, bipolar disorder, and major depression
Published in BMC bioinformatics (30-11-2011)“…Schizophrenia, bipolar disorder, and major depression are devastating mental diseases, each with distinctive yet overlapping epidemiologic characteristics…”
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Analysis of Protein-Protein Interactions in Cross-talk Pathways Reveals CRKL Protein as a Novel Prognostic Marker in Hepatocellular Carcinoma
Published in Molecular & cellular proteomics (01-05-2013)“…Deciphering the network of signaling pathways in cancer via protein-protein interactions (PPIs) at the cellular level is a promising approach but remains…”
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A stochastic differential equation model for quantifying transcriptional regulatory network in Saccharomyces cerevisiae
Published in Bioinformatics (15-06-2005)“…Motivation: The explosion of microarray studies has promised to shed light on the temporal expression patterns of thousands of genes simultaneously. However,…”
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SeqEntropy: genome-wide assessment of repeats for short read sequencing
Published in PloS one (27-03-2013)“…Recent studies on genome assembly from short-read sequencing data reported the limitation of this technology to reconstruct the entire genome even at very high…”
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Gene Expression Profiling and Pathway Network Analysis Predicts a Novel Antitumor Function for a Botanical-Derived Drug, PG2
Published in Evidence-based complementary and alternative medicine (01-01-2015)“…PG2 is a botanical drug that is mostly composed of Astragalus polysaccharides (APS). Its role in hematopoiesis and relieving cancer-related fatigue has…”
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Reconstruction of human protein interolog network using evolutionary conserved network
Published in BMC bioinformatics (10-05-2007)“…The recent increase in the use of high-throughput two-hybrid analysis has generated large quantities of data on protein interactions. Specifically, the…”
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POINeT: protein interactome with sub-network analysis and hub prioritization
Published in BMC bioinformatics (21-04-2009)“…Protein-protein interactions (PPIs) are critical to every aspect of biological processes. Expansion of all PPIs from a set of given queries often results in a…”
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POINT: a database for the prediction of protein–protein interactions based on the orthologous interactome
Published in Bioinformatics (22-11-2004)“…One possible path towards understanding the biological function of a target protein is through the discovery of how it interfaces within protein–protein…”
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MetaABC-an integrated metagenomics platform for data adjustment, binning and clustering
Published in Bioinformatics (15-08-2011)“…MetaABC is a metagenomic platform that integrates several binning tools coupled with methods for removing artifacts, analyzing unassigned reads and controlling…”
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A quantitative analysis of monochromaticity in genetic interaction networks
Published in BMC bioinformatics (30-11-2011)“…A genetic interaction refers to the deviation of phenotypes from the expected when perturbing two genes simultaneously. Studying genetic interactions help…”
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Quantitative assessment of mitochondrial DNA copies from whole genome sequencing
Published in BMC genomics (2012)“…Mitochondrial dysfunction is associated with various aging diseases. The copy number of mtDNA in human cells may therefore be a potential biomarker for…”
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Improving disulfide connectivity prediction with sequential distance between oxidized cysteines
Published in Bioinformatics (15-12-2005)“…Predicting disulfide connectivity precisely helps towards the solution of protein structure prediction. In this study, a descriptor derived from the sequential…”
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15
From Midbody Protein−Protein Interaction Network Construction to Novel Regulators in Cytokinesis
Published in Journal of proteome research (06-11-2009)“…Midbody, a transient organelle-like structure, is known as central for abscission and is indispensable for termination of cytokinesis. Here, we used the…”
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An evolutionary algorithm for large traveling salesman problems
Published in IEEE transactions on systems, man and cybernetics. Part B, Cybernetics (01-08-2004)“…This work proposes an evolutionary algorithm, called the heterogeneous selection evolutionary algorithm (HeSEA), for solving large traveling salesman problems…”
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Disulfide connectivity prediction with 70% accuracy using two-level models
Published in Proteins, structure, function, and bioinformatics (01-07-2006)“…Disulfide bridges stabilize protein structures covalently and play an important role in protein folding. Predicting disulfide connectivity precisely helps…”
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18
Co-expression of neighboring genes in the zebrafish (Danio rerio) genome
Published in International journal of molecular sciences (21-08-2009)“…Neighboring genes in the eukaryotic genome have a tendency to express concurrently, and the proximity of two adjacent genes is often considered a possible…”
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Detection of the inferred interaction network in hepatocellular carcinoma from EHCO (Encyclopedia of Hepatocellular Carcinoma genes Online)
Published in BMC bioinformatics (27-02-2007)“…The significant advances in microarray and proteomics analyses have resulted in an exponential increase in potential new targets and have promised to shed…”
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Seroprevalence and Associated Risk Factors of Toxocariasis among College Students in Taipei City, Taiwan
Published in Iranian journal of parasitology (01-07-2015)“…Infection by Toxocara spp. is known to be significantly associated with partial epilepsy. It has become popular for people to raise dogs/cats as pets and…”
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