Search Results - "Cheng, Zhaozhao"
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Changes in CSF sPDGFRβ level and their association with blood-brain barrier breakdown in Alzheimer's disease with or without small cerebrovascular lesions
Published in Alzheimer's research & therapy (14-03-2023)“…CSF-soluble platelet-derived growth factor receptor beta (sPDGFRβ) is closely associated with pericyte damage. However, the changes in CSF sPDGFRβ levels and…”
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CSF biomarkers of reactive glial cells are associated with blood-brain barrier leakage and white matter lesions
Published in Translational neurodegeneration (23-05-2024)Get full text
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Correlation of blood-brain barrier leakage with cerebral small vessel disease including cerebral microbleeds in Alzheimer's disease
Published in Frontiers in neurology (16-02-2023)“…Blood-brain barrier (BBB) damage is considered an important part of Alzheimer's disease (AD) progression, and cerebral small-vessel disease (CSVD) is commonly…”
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General anesthesia vs. non-general anesthesia for vertebrobasilar stroke endovascular therapy
Published in Frontiers in neurology (02-02-2023)“…The optimal type of anesthesia for acute vertebrobasilar artery occlusion (VBAO) remains controversial. We aimed to assess the influence of anesthetic…”
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Identification of hub proteins in cerebrospinal fluid as potential biomarkers of Alzheimer’s disease by integrated bioinformatics
Published in Journal of neurology (01-03-2023)“…Background Alzheimer’s disease (AD) is a heterogeneous neurodegenerative disease with complex pathophysiology. Therefore, the identification of novel effective…”
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High burdens of phosphorylated tau protein and distinct precuneus atrophy in sporadic early-onset Alzheimer’s disease
Published in Science bulletin (30-11-2023)“…[Display omitted] Early-onset Alzheimer’s disease (EOAD) is a rare devastating subclassification of Alzheimer’s disease (AD). EOAD affects…”
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A randomized, double‐blind, placebo‐controlled phase 1b study to evaluate the safety, tolerability, and pharmacodynamics of an anti‐amyloid‐β antibody SHR‐1707 in patients with mild cognitive impairment and mild Alzheimer’s disease
Published in Alzheimer's & dementia (01-12-2023)“…Background SHR‐1707 is a humanized monoclonal antibody against amyloid‐β (Aβ). Pharmacodynamic studies in vitro showed that SHR‐1707 is more potent than…”
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A combination model of AD biomarkers revealed by machine learning precisely predicts Alzheimer's dementia: China Aging and Neurodegenerative Initiative (CANDI) study
Published in Alzheimer's & dementia (01-03-2023)“…Introduction To test the utility of the “A/T/N” system in the Chinese population, we study core Alzheimer's disease (AD) biomarkers in a newly established…”
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Molecules of senescent glial cells differentiate Alzheimer’s disease from ageing
Published in Journal of neurology, neurosurgery and psychiatry (01-07-2023)“…BackgroundAgeing is a major risk factor for Alzheimer’s disease (AD), which is accompanied by cellular senescence and thousands of transcriptional changes in…”
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Changes in CSF sPDGFR[beta] level and their association with blood-brain barrier breakdown in Alzheimer's disease with or without small cerebrovascular lesions
Published in Alzheimer's research & therapy (14-03-2023)“…Background CSF-soluble platelet-derived growth factor receptor beta (sPDGFR[beta]) is closely associated with pericyte damage. However, the changes in CSF…”
Get full text
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Blood-based biomarkers for Alzheimer’s disease: a multicenter-based cross-sectional and longitudinal study in China
Published in Science bulletin (Beijing) (30-08-2023)“…[Display omitted] Discrepancies in diagnostic biomarkers for Alzheimer’s Disease (AD) may arise from racial disparities, risk factors, or lifestyle…”
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