Search Results - "Cheng, Zhanling"

Identification of a potent and specific retinoic acid-inducible gene 1 pathway activator as a Hepatitis B Virus antiviral through a novel cell-based reporter assay by Shi, Liping, Guo, Guangyang, Zhou, Jinying, Cheng, Zhanling, Zhu, Ren, Kukolj, George, Li, Chris

“…Chronic Hepatitis B Virus (HBV) infection remains a global burden. To identify small molecule RIG-I agonists as antivirals against HBV, we developed an…”
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Single-Molecule Conductance through Multiple π−π-Stacked Benzene Rings Determined with Direct Electrode-to-Benzene Ring Connections by Schneebeli, Severin T, Kamenetska, Maria, Cheng, Zhanling, Skouta, Rachid, Friesner, Richard A, Venkataraman, Latha, Breslow, Ronald

“…Understanding electron transport across π−π-stacked systems will help to answer fundamental questions about biochemical redox processes and benefit the design…”
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A facile synthesis of novel tricyclic 4-pyridones by Xu, Buzhe, Cheng, Zhanling, Fu, Lei

“…[Display omitted] A new and efficient synthesis of tricyclic 4-pyridone analogs through the intramolecular Heck coupling cyclization was described. This…”
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Discovery of RG7834: The First-in-Class Selective and Orally Available Small Molecule Hepatitis B Virus Expression Inhibitor with Novel Mechanism of Action by Han, Xingchun, Zhou, Chengang, Jiang, Min, Wang, Yongguang, Wang, Jianhua, Cheng, Zhanling, Wang, Min, Liu, Yongqiang, Liang, Chungen, Wang, Jianping, Wang, Zhanguo, Weikert, Robert, Lv, Wenzhe, Xie, Jianxun, Yu, Xin, Zhou, Xue, Luangsay, Souphalone, Shen, Hong C, Mayweg, Alexander V, Javanbakht, Hassan, Yang, Song

“…Chronic hepatitis B virus (HBV) infection is a serious public health burden, and current therapies cannot achieve satisfactory cure rate. There are high unmet…”
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C–H Bond Functionalization of Tetrahydropyridopyrimidines and Other Related Hetereocycles by Cheng, Zhanling, Yu, Zhiliang, Yang, Song, Shen, Hong C, Zhao, Weili, Zhong, Sheng

“…A novel and efficient 2-step method for the functionalization of the C–H bond adjacent to the amino group of tetrahydropyridopyrimidine (THPP) is reported…”
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