Search Results - "Cheng, Y. K. Y."

Desoxycorticosterone pivalate‐salt treatment leads to non‐dipping hypertension in Per1 knockout mice by Solocinski, K., Holzworth, M., Wen, X., Cheng, K.‐Y., Lynch, I. J., Cain, B. D., Wingo, C. S., Gumz, M. L.

“…Aim Increasing evidence demonstrates that circadian clock proteins are important regulators of physiological functions including blood pressure. An established…”
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Viral Shedding and Clinical Illness in Naturally Acquired Influenza Virus Infections by Lau, Lincoln L. H., Cowling, Benjamin J., Fang, Vicky J., Chan, Kwok-Hung, Lau, Eric H. Y., Lipsitch, Marc, Cheng, Calvin K. Y., Houck, Peter M., Uyeki, Timothy M., Peiris, J. S. Malik, Leung, Gabriel M.

“…Background. Volunteer challenge studies have provided detailed data on viral shedding from the respiratory tract before and through the course of experimental…”
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Vascular effects of adiponectin: molecular mechanisms and potential therapeutic intervention by Zhu, Weidong, Cheng, Kenneth K Y, Vanhoutte, Paul M, Lam, Karen S L, Xu, Aimin

“…Adiponectin is a major adipocyte-secreted adipokine abundantly present in the circulation as three distinct oligomeric complexes. In addition to its role as an…”
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Cryo-EM structures of a LptDE transporter in complex with Pro-macrobodies offer insight into lipopolysaccharide translocation by Botte, Mathieu, Ni, Dongchun, Schenck, Stephan, Zimmermann, Iwan, Chami, Mohamed, Bocquet, Nicolas, Egloff, Pascal, Bucher, Denis, Trabuco, Matilde, Cheng, Robert K. Y., Brunner, Janine D., Seeger, Markus A., Stahlberg, Henning, Hennig, Michael

“…Lipopolysaccharides are major constituents of the extracellular leaflet in the bacterial outer membrane and form an effective physical barrier for…”
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Fibroblastic reticular cells in lymph node potentiate white adipose tissue beiging through neuro-immune crosstalk in male mice by Cheong, Lai Yee, Wang, Baile, Wang, Qin, Jin, Leigang, Kwok, Kelvin H. M., Wu, Xiaoping, Shu, Lingling, Lin, Huige, Chung, Sookja Kim, Cheng, Kenneth K. Y., Hoo, Ruby L. C., Xu, Aimin

“…Lymph nodes (LNs) are always embedded in the metabolically-active white adipose tissue (WAT), whereas their functional relationship remains obscure. Here, we…”
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Protective Efficacy of Seasonal Influenza Vaccination against Seasonal and Pandemic Influenza Virus Infection during 2009 in Hong Kong by Cowling, Benjamin J., Ng, Sophia, Ma, Edward S. K., Cheng, Calvin K. Y., Wai, Winnie, Fang, Vicky J., Chan, Kwok-Hung, Ip, Dennis K. M., Chiu, Susan S., Peiris, J. S. Malik, Leung, Gabriel M.

“…Background. The relationship between seasonal influenza vaccine and susceptibility to 2009 pandemic A/H1N1 virus infection is not fully understood. Methods…”
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Facemasks and Hand Hygiene to Prevent Influenza Transmission in Households: A Cluster Randomized Trial by COWLING, Benjamin J, CHAN, Kwok-Hung, CHIU, Billy C. F, LEE, Paco W. Y, MING CHI CHIU, HOI CHE LEE, UYEKI, Timothy M, HOUCK, Peter M, PEIRIS, J. S. Malik, LEUNG, Gabriel M, FANG, Vicky J, CHENG, Calvin K. Y, FUNG, Rita O. P, WINNIE WAI, SIN, Joey, WING HONG SETO, YUNG, Raymond, CHU, Daniel W. S

“…Few data are available about the effectiveness of nonpharmaceutical interventions for preventing influenza virus transmission. To investigate whether hand…”
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Integrative single-cell and cell-free plasma RNA transcriptomics elucidates placental cellular dynamics by Tsang, Jason C. H., Vong, Joaquim S. L., Ji, Lu, Poon, Liona C. Y., Jiang, Peiyong, Lui, Kathy O., Ni, Yun-Bi, To, Ka Fai, Cheng, Yvonne K. Y., Chiu, Rossa W. K., Lo, Yuk Ming Dennis

“…The human placenta is a dynamic and heterogeneous organ critical in the establishment of the fetomaternal interface and the maintenance of gestational…”
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Structure of class B GPCR corticotropin-releasing factor receptor 1 by Hollenstein, Kaspar, Kean, James, Bortolato, Andrea, Cheng, Robert K. Y., Doré, Andrew S., Jazayeri, Ali, Cooke, Robert M., Weir, Malcolm, Marshall, Fiona H.

“…Structural analysis of class B G-protein-coupled receptors (GPCRs), cell-surface proteins that respond to peptide hormones, has been restricted to the…”
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Preliminary findings of a randomized trial of non-pharmaceutical interventions to prevent influenza transmission in households by Cowling, Benjamin J, Fung, Rita O P, Cheng, Calvin K Y, Fang, Vicky J, Chan, Kwok Hung, Seto, Wing Hong, Yung, Raymond, Chiu, Billy, Lee, Paco, Uyeki, Timothy M, Houck, Peter M, Peiris, J S Malik, Leung, Gabriel M

“…There are sparse data on whether non-pharmaceutical interventions can reduce the spread of influenza. We implemented a study of the feasibility and efficacy of…”
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Adiponectin-Induced Endothelial Nitric Oxide Synthase Activation and Nitric Oxide Production Are Mediated by APPL1 in Endothelial Cells by CHENG, Kenneth K. Y, LAM, Karen S. L, YU WANG, YU HUANG, CARLING, David, DONGHAI WU, CHIWAI WONG, AIMIN XU

“…Adiponectin-Induced Endothelial Nitric Oxide Synthase Activation and Nitric Oxide Production Are Mediated by APPL1 in Endothelial Cells Kenneth K.Y. Cheng 1 2…”
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Plasma DNA tissue mapping by genome-wide methylation sequencing for noninvasive prenatal, cancer, and transplantation assessments by Sun, Kun, Jiang, Peiyong, Chan, K. C. Allen, Wong, John, Cheng, Yvonne K. Y., Liang, Raymond H. S., Chan, Wai-kong, Ma, Edmond S. K., Chan, Stephen L., Cheng, Suk Hang, Chan, Rebecca W. Y., Tong, Yu K., Ng, Simon S. M., Wong, Raymond S. M., Hui, David S. C., Leung, Tse Ngong, Leung, Tak Y., Lai, Paul B. S., Chiu, Rossa W. K., Lo, Yuk Ming Dennis

“…Plasma consists of DNA released from multiple tissues within the body. Using genome-wide bisulfite sequencing of plasma DNA and deconvolution of the sequencing…”
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Noninvasive twin zygosity assessment and aneuploidy detection by maternal plasma DNA sequencing by Leung, Tak Y., Qu, James Z. Z., Liao, Gary J. W., Jiang, Peiyong, Cheng, Yvonne K. Y., Chan, K. C. Allen, Chiu, Rossa W. K., Lo, Y. M. Dennis

“…ABSTRACT Objective This study aimed to provide an individualized assessment of fetal trisomy 21 and trisomy 18 status for twin pregnancies by maternal plasma…”
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Effects of Oseltamivir Treatment on Duration of Clinical Illness and Viral Shedding and Household Transmission of Influenza Virus by Ng, Sophia, Cowling, Benjamin J., Fang, Vicky J., Chan, Kwok Hung, Ip, Dennis K. M., Cheng, Calvin K. Y., Uyeki, Timothy M., Houck, Peter M., Peiris, J. S. Malik, Leung, Gabriel M.

“…Background. Large clinical trials have demonstrated the therapeutic efficacy of oseltamivir against influenza. We assessed the indirect effectiveness of…”
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The crystal structure of the human polo-like kinase-1 polo box domain and its phospho-peptide complex by Cheng, Kin-Yip, Lowe, Edward D, Sinclair, John, Nigg, Erich A, Johnson, Louise N

“…Human polo‐like kinase Plk1 localizes to the centrosomes, kinetochores and central spindle structures during mitosis. It plays an essential role in promoting…”
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Increased risk of subdural hematoma in patients with liver cirrhosis by Lin, Y-T, Cheng, Y-K, Lin, C-L, Wang, I-K

“…Subdural hematoma (SDH) is associated with a high mortality rate. The risk of SDH in cirrhotic patients has not been well studied. The aim of the study was to…”
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Size-tagged preferred ends in maternal plasma DNA shed light on the production mechanism and show utility in noninvasive prenatal testing by Sun, Kun, Jiang, Peiyong, Wong, Ada I. C., Cheng, Yvonne K. Y., Cheng, Suk Hang, Zhang, Haiqiang, Chan, K. C. Allen, Leung, Tak Y., Chiu, Rossa W. K., Lo, Y. M. Dennis

“…Cell-free DNA in human plasma is nonrandomly fragmented and reflects genomewide nucleosomal organization. Previous studies had demonstrated tissue-specific…”
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Controlling the Dissociation of Ligands from the Adenosine A2A Receptor through Modulation of Salt Bridge Strength by Segala, Elena, Guo, Dong, Cheng, Robert K. Y, Bortolato, Andrea, Deflorian, Francesca, Doré, Andrew S, Errey, James C, Heitman, Laura H, IJzerman, Adriaan P, Marshall, Fiona H, Cooke, Robert M

“…The association and dissociation kinetics of ligands binding to proteins vary considerably, but the mechanisms behind this variability are poorly understood,…”
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Clinical and immunochemical profiles of food challenge proven or anaphylactic shrimp allergy in tropical Singapore by Thalayasingam, M., Gerez, I. F. A., Yap, G. C., Llanora, G. V., Chia, I. P., Chua, L., Lee, C. J. A. O., Ta, L. D. H., Cheng, Y. K., Thong, B. Y. H., Tang, C. Y., Van Bever, H. P. S., Shek, L. P., Curotto de Lafaille, M. A., Lee, B. W.

“…Summary Background Shellfish allergy in Singapore is highly prevalent, and shrimp allergy is the most common. Objective This study aims to evaluate the…”
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Effects of pig manure compost and nonionic-surfactant Tween 80 on phenanthrene and pyrene removal from soil vegetated with Agropyron elongatum by Cheng, K.Y., Lai, K.M., Wong, J.W.C.

“…This paper evaluates the effects of pig manure compost (PMC) and Tween 80 on the removal of phenanthrene (PHE) and pyrene (PYR) from soil cultivated with…”
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