Search Results - "Cheng, Xiayun"

Synthesis of Neurotrophic Seco-prezizaane Sesquiterpenes (1R,10S)-2-Oxo-3,4-dehydroneomajucin, (2S)-Hydroxy-3,4-dehydroneomajucin, and (-)-Jiadifenin by Cheng, Xiayun, Micalizio, Glenn C

“…An asymmetric approach to the synthesis of neurotrophic seco-prezizaane sesquiterpenes is described that is based on the strategic application of a…”
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An Annulation Reaction for the Synthesis of Cross-Conjugated Triene-Containing Hydroindanes from Acyclic Precursors by Cheng, Xiayun, Micalizio, Glenn C

“…In efforts directed toward the synthesis of seco-prezizaane sesquiterpenoids, a stereoselective annulation reaction has been developed between…”
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Concise Total Syntheses of the Lycopodium Alkaloids (±)-Nankakurines A and B via Luciduline by Cheng, Xiayun, Waters, Stephen P

“…Total syntheses of the Lycopodium alkaloids nankakurines A and B have been accomplished in 6 and 7 steps, respectively, via a sequence that passes through a…”
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Total Synthesis of the Aspidosperma Alkaloid (±)-Subincanadine F via a Titanium-Mediated Intramolecular Nucleophilic Acyl Substitution Strategy by Cheng, Xiayun, Duhaime, Chelsea M, Waters, Stephen P

“…The total synthesis of the bridge-fused Aspidosperma indole alkaloid (±)-subincanadine F has been accomplished in seven steps. The synthetic utility of a…”
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Synthesis of Substituted 2‑Pyridones via 6π-Electrocyclization of Dienyl Isocyanates by Cheng, Xiayun, Taylor, Alexandria P, Zhu, Kaicheng

“…A one-pot Curtius rearrangement of dienyl carboxylic acids followed by a 6π-electrocyclization process to form substituted 2-pyridone products has been…”
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Pyridone Annulation via Tandem Curtius Rearrangement/6π-Electrocyclization: Total Synthesis of (−)-Lyconadin C by Cheng, Xiayun, Waters, Stephen P

“…A concise, enantioselective total synthesis of the Lycopodium alkaloid (−)-lyconadin C was achieved in 12 steps and high overall yield. Key features include…”
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Synthesis of 2‑Arylpiperidines via Pd-Catalyzed Arylation of Aza-Achmatowicz Rearrangement Products with Arylboronic Acids by Zhao, Guodong, Canterbury, Daniel P, Taylor, Alexandria P, Cheng, Xiayun, Mikochik, Peter, Bagley, Scott W, Tong, Rongbiao

“…The first Pd-catalyzed arylation of aza-Achmatowicz rearrangement products with arylboronic acids is achieved, providing versatile 2-aryldihydropyridinones for…”
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Synthesis of Angularly Substituted Trans-Fused Hydroindanes by Convergent Coupling of Acyclic Precursors by Jeso, Valer, Aquino, Claudio, Cheng, Xiayun, Mizoguchi, Haruki, Nakashige, Mika, Micalizio, Glenn C

“…Angularly substituted trans-fused hydroindanes are now accessible by the direct and convergent union of trimethylsilyl (TMS)-alkynes with 4-hydroxy-1,6-enynes…”
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Discovery of High-Affinity Small-Molecule Binders of the Epigenetic Reader YEATS4 by Londregan, Allyn T., Aitmakhanova, Karlygash, Bennett, James, Byrnes, Laura J., Canterbury, Daniel P., Cheng, Xiayun, Christott, Thomas, Clemens, Jennifer, Coffey, Steven B., Dias, João M., Dowling, Matthew S., Farnie, Gillian, Fedorov, Oleg, Fennell, Kimberly F., Gamble, Vicki, Gileadi, Carina, Giroud, Charline, Harris, Michael R., Hollingshead, Brett D., Huber, Kilian, Korczynska, Magdalena, Lapham, Kimberly, Loria, Paula M., Narayanan, Arjun, Owen, Dafydd R., Raux, Brigitt, Sahasrabudhe, Parag V., Ruggeri, Roger B., Sáez, Laura Díaz, Stock, Ingrid A., Thuma, Benjamin A., Tsai, Andy, Varghese, Alison E.

“…A series of small-molecule YEATS4 binders have been discovered as part of an ongoing research effort to generate high-quality probe molecules for emerging…”
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Total Synthesis of the Aspidosperma Alkaloid (±)-Subineanadine F via a Titanium-Mediated Intramolecular Nucleophilic Acyl Substitution Strategy by XIAYUN CHENG, DUHAIME, Chelsea M, WATERS, Stephen P

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Synthesis of Neurotrophic Seco-prezizaane Sesquiterpenes (1R,10S)‑2-Oxo-3,4-dehydro­neomajucin, (2S)‑Hydroxy-3,4-dehydroneo­majucin, and (−)-Jiadifenin by Cheng, Xiayun, Micalizio, Glenn C

“…An asymmetric approach to the synthesis of neurotrophic seco-prezizaane sesquiterpenes is described that is based on the strategic application of a…”
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