Search Results - "Cheng, Xian Wu"

Role of Dipeptidyl Peptidase-4 in Atherosclerotic Cardiovascular Disease in Humans and Animals with Chronic Stress by Piao, Limei, Li, Yanglong, Narisawa, Megumi, Shen, Xionghu, Cheng, Xian Wu

“…Exposure to psychosocial stress is a risk factor for cardiovascular disease, including vascular atherosclerosis-based cardiovascular disease (ACVD). Dipeptidyl…”
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Indoxyl Sulfate Activates NLRP3 Inflammasome to Induce Cardiac Contractile Dysfunction Accompanied by Myocardial Fibrosis and Hypertrophy by Yamaguchi, Kazutoshi, Yisireyili, Maimaiti, Goto, Sumie, Cheng, Xian Wu, Nakayama, Takayuki, Matsushita, Tadashi, Niwa, Toshimitsu, Murohara, Toyoaki, Takeshita, Kyosuke

“…In patients with chronic kidney diseases (CKD), high serum indoxyl sulfate (IS) levels correlate with cardiac fibrosis and hypertrophy and thus a critical risk…”
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Immune Disorder in Atherosclerotic Cardiovascular Disease　― Clinical Implications of Using Circulating T-Cell Subsets as Biomarkers by Neupane, Rajib, Jin, Xiongjie, Sasaki, Takeshi, Li, Xiang, Murohara, Toyoaki, Cheng, Xian Wu

“…Atherosclerotic cardiovascular disease (ACVD) is an inflammatory phenomenon that leads to structural abnormality in the vascular lumen due to the formation of…”
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Notch1 haploinsufficiency in mice accelerates adipogenesis by Yamaguchi, Kazutoshi, Hayashi, Motoharu, Uchida, Yasuhiro, Cheng, Xian Wu, Nakayama, Takayuki, Matsushita, Tadashi, Murohara, Toyoaki, Takeshita, Kyosuke

“…Notch signaling has been recognized recently as a key regulator of metabolism. Here, we determined the role of Notch1 in adipogenesis in wild-type (WT) and…”
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Cathepsin K Deficiency Impaired Ischemia-Induced Neovascularization in Aged Mice by Xia, Manli, Xu, Ying, Jiang, Haiying, Yue, Xueling, Cheng, Xian-Wu

“…Background. Aging is a major risk factor for cardiovascular disease. Cysteine protease cathepsin K (CatK) has been implicated in the process of angiogenesis,…”
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Differential Patterns of Secreted Frizzled-Related Protein 4 (SFRP4) in Adipocyte Differentiation: Adipose Depot Specificity by Guan, Hua, Zhang, Yali, Gao, Shoucui, Bai, Liang, Zhao, Sihai, Cheng, Xian Wu, Fan, Jianglin, Liu, Enqi 

“…Background/Aims: Secreted frizzled-related protein 4 (SFRP4) is a member of the SFRP family that acts as soluble modulators of Wnt signaling. Given the…”
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Effect of MMP-2 Deficiency on Atherosclerotic Lesion Formation in ApoE-Deficient Mice by Kuzuya, Masafumi, Nakamura, Kae, Sasaki, Takeshi, Cheng, Xian Wu, Itohara, Shigeyoshi, Iguchi, Akihisa

“…OBJECTIVE—Although it has been reported that matrix metalloproteinase (MMP)-2 is a major proteinase in atherosclerotic plaque lesions, there is no direct…”
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Does inclusion of bioactive n-3 PUFAs in parenteral nutrition benefit postoperative patients undergoing liver surgery? A systematic review and meta-analysis of randomised control trials by He, Zheng-Wei, Wang, Chao, Li, Yong, Danzeng, Awang, Liu, Fu-Bin, Shi, Jia-Yu, Ciren, Pingcuo, Yuan, Xiao-Yin, Wu, Cheng-Xian, Lan, Run-hu, Zhang, Bin-Hao

“…Objectives This meta-analysis aims to evaluate the effect of n-3 polyunsaturated fatty acids (PUFAs) as a part of parenteral nutrition in patients undergoing…”
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Cathepsin K-mediated notch1 activation contributes to neovascularization in response to hypoxia by Jiang, Haiying, Wu Cheng, Xian, Shi, Guo-Ping, Hu, Lina, Inoue, Aiko, Yamamura, Yumiko, Wu, Hongxian, Takeshita, Kyosuke, Li, Xiang, Huang, Zhe, Song, Haizhen, Asai, Masashi, Hao, Chang-Ning, Unno, Kazumasa, Koike, Teruhiro, Oshida, Yoshiharu, Okumura, Kenji, Murohara, Toyoaki, Kuzuya, Masafumi

“…Cysteine proteases play important roles in pathobiology. Here we reveal that cathepsin K (CatK) has a role in ischaemia-induced neovascularization. Femoral…”
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Xanthine oxidase inhibition by febuxostat attenuates stress-induced hyperuricemia, glucose dysmetabolism, and prothrombotic state in mice by Yisireyili, Maimaiti, Hayashi, Motoharu, Wu, Hongxian, Uchida, Yasuhiro, Yamamoto, Koji, Kikuchi, Ryosuke, Shoaib Hamrah, Mohammad, Nakayama, Takayuki, Wu Cheng, Xian, Matsushita, Tadashi, Nakamura, Shigeo, Niwa, Toshimitsu, Murohara, Toyoaki, Takeshita, Kyosuke

“…Chronic stress is closely linked to the metabolic syndrome, diabetes, hyperuricemia and thromboembolism, but the mechanisms remain elusive. We reported…”
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Granulocyte colony-stimulating factor protected against brain injury in a rat cerebral hemorrhage model by modulating inflammation by Li, Yanglong, Piao, Xianji, Xu, Tiance, Zhang, Binbin, Shen, Xionghu, Cheng, Xian Wu, Zheng, Shengzhe

“…Granulocyte colony-stimulating factor (G-CSF) has been reported to exert a protective effect against secondary brain damage, but the underlying mechanisms…”
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Dipeptidyl peptidase-4 inhibition prevents lung injury in mice under chronic stress via the modulation of oxidative stress and inflammation by Zhang, Shengming, Li, Ping, Xin, Minglong, Jin, Xianglan, Zhao, Longguo, Nan, Yongshan, Cheng, Xian Wu

“…Exposure to chronic psychosocial stress is a risk factor for various pulmonary diseases. In view of the essential role of dipeptidyl peptidase 4 (DPP4) in…”
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Cathepsin S-Mediated Negative Regulation of Wnt5a/SC35 Activation Contributes to Ischemia-Induced Neovascularization in Aged Mice by Xu, Wenhu, Yu, Chenglin, Piao, Limei, Inoue, Aiko, Wang, Hailong, Meng, Xiangkun, Li, Xiang, Cui, Lan, Umegaki, Hiroyuki, Shi, Guo-Ping, Murohara, Toyoaki, Kuzuya, Masafumi, Cheng, Xian Wu

“…Background:Given that cathepsin S (CatS) gained attention due to its enzymatic and non-enzymatic functions in signaling, the role of CatS in ischemia-induced…”
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Can cysteinyl cathepsin activity control diet-induced NAFLD? by Yu, Chenglin, Wan, Ying, Piao, Limei, Wu Cheng, Xian

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Impact of circulating cathepsin K on the coronary calcification and the clinical outcome in chronic kidney disease patients by Izumi, Yusuke, Hayashi, Mutsuharu, Morimoto, Ryota, Cheng, Xian Wu, Wu, Hongxian, Ishii, Hideki, Yasuda, Yoshinari, Yoshikawa, Daiji, Izawa, Hideo, Matsuo, Seiichi, Oiso, Yutaka, Murohara, Toyoaki

“…Chronic kidney disease (CKD) is a cause of coronary artery calcification (CAC) and an independent predictor of major adverse cardiac and cerebrovascular events…”
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Characteristics of blood pressure profiles and vascular dysfunction by Okumura, Kenji, Cheng, Xian Wu

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Impact of the combination of an angiotensin II receptor blocker and low-dose hydrochlorothiazide on patients with morning hypertension by Cheng, Xian Wu, Murohara, Toyoaki

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GW29-e1933 sGC signaling improve detoxification of mitochondrial iron in doxorubicin-induced cardiomyopathy by Zhao, Xiaoxiao, Cheng, Xian Wu

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Regulation of Apelin and Its Receptor Expression in Adipose Tissues of Obesity Rats with Hypertension and Cultured 3T3-L1 Adipocytes by Wu, Hongxian, Cheng, Xian Wu, Hao, Changning, Zhang, Zhi, Yao, Huali, Murohara, Toyoaki, Dai, Qiuyan

“…The apelin/APJ system has been implicated in obesity-related hypertension. We investigated the mechanism responsible for the pathogenesis of obesity-related…”
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Endothelial function for the evaluation of anti-atherosclerotic drugs by Okumura, Kenji, Cheng, Xian Wu

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