Search Results - "Cheng, Wenxiang"
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Interlayer Structure Engineering of MXene‐Based Capacitor‐Type Electrode for Hybrid Micro‐Supercapacitor toward Battery‐Level Energy Density
Published in Advanced science (01-08-2021)“…Micro‐supercapacitors are notorious for their low energy densities compared to micro‐batteries. While MXenes have been identified as promising capacitor‐type…”
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Biodegradable Magnesium Screws Accelerate Fibrous Tissue Mineralization at the Tendon-Bone Insertion in Anterior Cruciate Ligament Reconstruction Model of Rabbit
Published in Scientific reports (10-01-2017)“…The incorporation of tendon graft into bone tunnel is one of the most challenging clinical issues in anterior cruciate ligament (ACL) reconstruction. As a…”
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Cell life-or-death events in osteoporosis: All roads lead to mitochondrial dynamics
Published in Pharmacological research (01-10-2024)“…Mitochondria exhibit heterogeneous shapes and networks within and among cell types and tissues, also in normal or osteoporotic bone tissues with complex cell…”
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Shang-Ke-Huang-Shui and coptisine alleviate osteoarthritis in the knee of monosodium iodoacetate-induced rats through inhibiting CXCR4 signaling
Published in Journal of ethnopharmacology (15-07-2023)“…Shang-Ke-Huang-Shui (SKHS) is a classic traditional Chinese medicine formula originally from the southern China city of Foshan. It has been widely used in the…”
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Peptide-based inhibitors hold great promise as the broad-spectrum agents against coronavirus
Published in Frontiers in microbiology (19-01-2023)“…Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV), Middle East Respiratory Syndrome (MERS), and the recent SARS-CoV-2 are lethal coronaviruses (CoVs)…”
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Repurposing of Pirfenidone (Anti-Pulmonary Fibrosis Drug) for Treatment of Rheumatoid Arthritis
Published in Frontiers in pharmacology (05-03-2021)“…Clinical studies have shown that pirfenidone (PFD) effectively relieves joint pain in rheumatoid arthritis (RA) patients. However, the detailed mechanisms…”
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New use for old drug: Local delivery of puerarin facilitates critical-size defect repair in rats by promoting angiogenesis and osteogenesis
Published in Journal of orthopaedic translation (01-09-2022)“…Large bone defect repair is a challenging clinical problem due to limited self-repair ability. A well-designed bone filling product should possess the ability…”
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Magnetic resonance imaging classification in a percutaneous needle injury rat model of intervertebral disc degeneration
Published in Journal of orthopaedic surgery and research (07-10-2024)“…During the development of disease-modifying intervertebral disc degeneration (IDD) drugs, the rat model of IDD is frequently used for disease progression…”
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Biphasic Effect of Pirfenidone on Angiogenesis
Published in Frontiers in pharmacology (05-01-2022)“…Pirfenidone (PFD), a synthetic arsenic compound, has been found to inhibit angiogenesis at high concentrations. However, the biphasic effects of different PFD…”
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Downregulation of Hypoxia-Inducible Factor-1α by RNA Interference Alleviates the Development of Collagen-Induced Arthritis in Rats
Published in Molecular therapy. Nucleic acids (06-03-2020)“…Rheumatoid arthritis (RA) is the most common type of autoimmune arthritis. Hypoxia-inducible factor-1α (HIF-1α) as a transcription factor in response to…”
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Study in Treatment of Collagen-Induced Arthritis in DBA/1 Mice Model by Genistein
Published in Current pharmaceutical design (01-01-2016)“…This work aimed to evaluate the effects of genistein treatment in Collagen Induced Arthritis (CIA) mouse model. CIA was elicited in DBA/1 Mice by an…”
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Treatment of collagen-induced arthritis rat model by using Notch signalling inhibitor
Published in Journal of orthopaedic translation (01-05-2021)“…The Notch signalling pathway has been reported to play a key role in rheumatoid arthritis (RA) development. Thus, inhibition of the activation of this…”
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Fracture healing in a collagen‐induced arthritis rat model: Radiology and histology evidence
Published in Journal of orthopaedic research (01-11-2018)“…ABSTRACT This research was designed to investigate the fracture healing pattern in a rheumatoid arthritis (RA) rat model. A mid‐shaft femur fracture (RA + F)…”
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Genistein: the potential for efficacy in rheumatoid arthritis
Published in Clinical rheumatology (01-05-2013)“…Rheumatoid arthritis (RA) is a chronic, systemic inflammatory disorder that may affect many tissues and organs. Without treatment, inflammation leads to…”
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HIF-1α dependent RhoA as a novel therapeutic target to regulate rheumatoid arthritis fibroblast-like synoviocytes migration in vitro and in vivo
Published in Journal of orthopaedic translation (01-05-2023)“…The purpose of this work is to investigate how the Rho family of GTPases A (RhoA) mediates the pathogenesis of rheumatoid arthritis fibroblast-like…”
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A Three-Dimensional Co-Culture Model for Rheumatoid Arthritis Pannus Tissue
Published in Frontiers in bioengineering and biotechnology (12-11-2021)“…Three-dimensional (3D) co-culture models have closer physiological cell composition and behavior than traditional 2D culture. They exhibit pharmacological…”
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Anti-inflammatory effects of Jingshu Keli capsule and its components on human synoviocyte MH7A cells
Published in Arthroplasty (09-03-2020)“…Jingshu Keli (JSKL), a traditional Chinese medicine (TCM) formula consisting of multiple active compounds, has been officially approved by National Medical…”
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The effect and mechanism of QufengZhitong capsule for the treatment of osteoarthritis in a rat model
Published in Journal of orthopaedic translation (01-05-2021)“…The purpose of this study was to evaluate the therapeutic effects and mechanism of Qufeng Zhitong (QFZT)capsule for the treatment of osteoarthritis (OA) in a…”
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Qu Feng Zhi Tong capsule increases mechanical properties of cortical bone in ovariectomised rats
Published in Journal of orthopaedic translation (01-11-2020)“…Qu Feng Zhi Tong capsule (QF, Buchang Pharma, Xi'an, Shanxi, China) is officially approved Fufang formula in China for the treatment of rheumatoid arthritis…”
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Attenuation of collagen-induced arthritis by potential anti-inflammatory drug genistein in DBA/1 mice
Published in Journal of orthopaedic translation (01-10-2016)Get full text
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