Search Results - "Cheng, Wayland Wl"

Direct binding of phosphatidylglycerol at specific sites modulates desensitization of a ligand-gated ion channel by Tong, Ailing, Petroff, 2nd, John T, Hsu, Fong-Fu, Schmidpeter, Philipp Am, Nimigean, Crina M, Sharp, Liam, Brannigan, Grace, Cheng, Wayland Wl

“…Pentameric ligand-gated ion channels (pLGICs) are essential determinants of synaptic transmission, and are modulated by specific lipids including anionic…”
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Polyunsaturated fatty acids inhibit a pentameric ligand-gated ion channel through one of two binding sites by Dietzen, Noah M, Arcario, Mark J, Chen, Lawrence J, Petroff, 2nd, John T, Moreland, K Trent, Krishnan, Kathiresan, Brannigan, Grace, Covey, Douglas F, Cheng, Wayland Wl

“…Polyunsaturated fatty acids (PUFAs) inhibit pentameric ligand-gated ion channels (pLGICs) but the mechanism of inhibition is not well understood. The PUFA,…”
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Site-specific effects of neurosteroids on GABAA receptor activation and desensitization by Sugasawa, Yusuke, Cheng, Wayland WL, Bracamontes, John R, Chen, Zi-Wei, Wang, Lei, Germann, Allison L, Pierce, Spencer R, Senneff, Thomas C, Krishnan, Kathiresan, Reichert, David E, Covey, Douglas F, Akk, Gustav, Evers, Alex S

“…This study examines how site-specific binding to three identified neurosteroid-binding sites in the α 1 β 3 GABA A receptor (GABA A R) contributes to…”
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Site-specific effects of neurosteroids on GABA A receptor activation and desensitization by Sugasawa, Yusuke, Cheng, Wayland Wl, Bracamontes, John R, Chen, Zi-Wei, Wang, Lei, Germann, Allison L, Pierce, Spencer R, Senneff, Thomas C, Krishnan, Kathiresan, Reichert, David E, Covey, Douglas F, Akk, Gustav, Evers, Alex S

“…This study examines how site-specific binding to three identified neurosteroid-binding sites in the α β GABA receptor (GABA R) contributes to neurosteroid…”
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The molecular determinants of neurosteroid binding in the GABA(A) receptor by Sugasawa, Yusuke, Bracamontes, John R., Krishnan, Kathiresan, Covey, Douglas F., Reichert, David E., Akk, Gustav, Chen, Qiang, Tang, Pei, Evers, Alex S., Cheng, Wayland W.L.

“…•Neurosteroids photolabel ELIC-α1GABAAR at an intersubunit and intrasubunit site.•Mutations in the intersubunit site do not reduce neurosteroid…”
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Three classes of propofol binding sites on GABA A receptors by Chen, Zi-Wei, Chintala, Satyanarayana M, Bracamontes, John, Sugasawa, Yusuke, Pierce, Spencer R, Varga, Balazs R, Smith, Edward H, Edge, Christopher J, Franks, Nicholas P, Cheng, Wayland Wl, Akk, Gustav, Evers, Alex S

“…Propofol is a widely used anesthetic and sedative that acts as a positive allosteric modulator (PAM) of gamma-aminobutyric acid type A (GABA ) receptors…”
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Dual-Mode Phospholipid Regulation of Human Inward Rectifying Potassium Channels by Cheng, Wayland W.L., D'Avanzo, Nazzareno, Doyle, Declan A., Nichols, Colin G.

“…The lipid bilayer is a critical determinant of ion channel activity; however, efforts to define the lipid dependence of channel function have generally been…”
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KirBac1.1: it's an inward rectifying potassium channel by Cheng, Wayland W L, Enkvetchakul, Decha, Nichols, Colin G

“…KirBac1.1 is a prokaryotic homologue of eukaryotic inward rectifier potassium (Kir) channels. The crystal structure of KirBac1.1 and related KirBac3.1 have now…”
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