Search Results - "Cheng, S. Y."

Pembrolizumab plus Chemotherapy in Metastatic Non–Small-Cell Lung Cancer by Gandhi, Leena, Rodríguez-Abreu, Delvys, Gadgeel, Shirish, Esteban, Emilio, Felip, Enriqueta, De Angelis, Flávia, Domine, Manuel, Clingan, Philip, Hochmair, Maximilian J, Powell, Steven F, Cheng, Susanna Y.-S, Bischoff, Helge G, Peled, Nir, Grossi, Francesco, Jennens, Ross R, Reck, Martin, Hui, Rina, Garon, Edward B, Boyer, Michael, Rubio-Viqueira, Belén, Novello, Silvia, Kurata, Takayasu, Gray, Jhanelle E, Vida, John, Wei, Ziwen, Yang, Jing, Raftopoulos, Harry, Pietanza, M. Catherine, Garassino, Marina C

“…The addition of pembrolizumab to chemotherapy for metastatic lung cancer without EGFR or ALK mutations resulted in better progression-free and overall survival…”
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Elevated CO2 concentration impacts cell wall polysaccharide composition of green microalgae of the genus Chlorella by Cheng, Y.‐S, Labavitch, J.M, VanderGheynst, J.S

“…The effect of CO₂concentration on the relative content of starch, lipid and cell wall carbohydrates in microalgal biomass was investigated for the four…”
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Nitric oxide and redox mechanisms in the immune response by Wink, David A., Hines, Harry B., Cheng, Robert Y. S., Switzer, Christopher H., Flores‐Santana, Wilmarie, Vitek, Michael P., Ridnour, Lisa A., Colton, Carol A.

“…Review discusses the chemistry of NO and ROS in the context of anti‐pathogen activity and immunoregulation. The role of redox molecules, such as NO and ROS, as…”
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Geographic trends in incidence of hip fractures: a comprehensive literature review by Cheng, S. Y., Levy, A. R, Lefaivre, K. A., Guy, P., Kuramoto, L., Sobolev, B.

“…Summary A comprehensive review of literature was conducted to investigate variation in hip fracture incident rates around the world. The original crude…”
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EGFRvIII stimulates glioma growth and invasion through PKA-dependent serine phosphorylation of Dock180 by Feng, H, Hu, B, Vuori, K, Sarkaria, J N, Furnari, F B, Cavenee, W K, Cheng, S-Y

“…Glioblastomas (GBMs), the most common and malignant brain tumors, are highly resistant to current therapies. The failure of targeted therapies against…”
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Coexpression of NOS2 and COX2 accelerates tumor growth and reduces survival in estrogen receptor-negative breast cancer by Basudhar, Debashree, Glynn, Sharon A., Greer, Madison, Somasundaram, Veena, No, Jae Hong, Scheiblin, David A., Garrido, Pablo, Heinz, William F., Ryan, Aideen E., Weiss, Jonathan M., Cheng, Robert Y. S., Ridnour, Lisa A., Lockett, Stephen J., McVicar, Daniel W., Ambs, Stefan, Wink, David A.

“…Proinflammatory signaling pathways are commonly up-regulated in breast cancer. In estrogen receptor-negative (ER⁻) and triple-negative breast cancer (TNBC),…”
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A measure of second language writing anxiety: Scale development and preliminary validation by Cheng, Y.-S.

“…Evidence has been accumulating that shows the promise of multidimensional conceptualizations of anxiety in investigating the effects of anxiety on different…”
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Tumor microenvironment-based feed-forward regulation of NOS2 in breast cancer progression by Heinecke, Julie L., Ridnour, Lisa A., Cheng, Robert Y. S., Switzer, Christopher H., Lizardo, Michael M., Khanna, Chand, Glynn, Sharon A., Hussain, S. Perwez, Young, Howard A., Ambs, Stefan, Wink, David A.

“…Inflammation is widely recognized as an inducer of cancer progression. The inflammation-associated enzyme, inducible nitric oxide synthase (NOS2), has emerged…”
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Artificial intelligence significantly improves the diagnostic accuracy of deep myxoid soft tissue lesions in histology by Yeung, Maximus C. F., Cheng, Ivy S. Y.

“…Deep myxoid soft tissue lesions have posed a diagnostic challenge for pathologists due to significant histological overlap and regional heterogeneity,…”
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CD97 amplifies LPA receptor signaling and promotes thyroid cancer progression in a mouse model by Ward, Y, Lake, R, Martin, P L, Killian, K, Salerno, P, Wang, T, Meltzer, P, Merino, M, Cheng, S-y, Santoro, M, Garcia-Rostan, G, Kelly, K

“…CD97, a member of the adhesion family of G-protein-coupled receptors (GPCRs), complexes with and potentiates lysophosphatidic acid (LPA) receptor signaling to…”
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EGFRvIII promotes glioma angiogenesis and growth through the NF-κB, interleukin-8 pathway by Bonavia, R, Inda, M M, Vandenberg, S, Cheng, S-Y, Nagane, M, Hadwiger, P, Tan, P, Sah, D W Y, Cavenee, W K, Furnari, F B

“…Sustaining a high growth rate requires tumors to exploit resources in their microenvironment. One example of this is the extensive angiogenesis that is a…”
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Neuropilin-1 promotes human glioma progression through potentiating the activity of the HGF SF autocrine pathway by HU, B, GUO, P, BAR-JOSEPH, I, IMANISHI, Y, JARZYNKA, M. J, BOGLER, O, MIKKELSEN, T, HIROSE, T, NISHIKAWA, R, CHENG, S. Y

“…Neuropilin-1 (NRP1) functions as a coreceptor through interaction with plexin A1 or vascular endothelial growth factor (VEGF) receptor during neuronal…”
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Positron emission tomography (18)F-fluorodeoxyglucose uptake and prognosis in patients with bone and soft tissue sarcoma: a meta-analysis by Li, Yong-Jiang, Dai, Yi-Ling, Cheng, Yi-Song, Zhang, Wen-Biao, Tu, Chong-Qi

“…Abstract Purpose To investigate the prognostic significance of (18)F-FDG PET imaging in patients with bone and soft tissue sarcoma, a meta-analysis was…”
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NOS2 and COX-2 Co-Expression Promotes Cancer Progression: A Potential Target for Developing Agents to Prevent or Treat Highly Aggressive Breast Cancer by Coutinho, Leandro L, Femino, Elise L, Gonzalez, Ana L, Moffat, Rebecca L, Heinz, William F, Cheng, Robert Y S, Lockett, Stephen J, Rangel, M Cristina, Ridnour, Lisa A, Wink, David A

“…Nitric oxide (NO) and reactive nitrogen species (RNS) exert profound biological impacts dictated by their chemistry. Understanding their spatial distribution…”
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Evaluation of biodegradable paclitaxel-eluting nanofibre-covered metal stents for the treatment of benign cardia stricture in an experimental model by Zhu, Y.-Q., Cui, W.-G., Cheng, Y.-S., Chang, J., Chen, N.-W., Yan, L.

“…Background Benign strictures at the cardia are troublesome for patients and often require repeated endoscopic treatments. Paclitaxel can reduce fibrosis. This…”
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Hedgehog signaling promotes the degradation of tumor suppressor Sufu through the ubiquitin-proteasome pathway by Yue, S, Chen, Y, Cheng, S Y

“…Sustained Sonic hedgehog (Shh) pathway activity is associated with tumorigenesis in a wide variety of tissues. Mutational inactivation of Shh receptor Patched…”
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Neural circuitry of play fighting in golden hamsters by Cheng, S.-Y, Taravosh-Lahn, K, Delville, Y

“…Abstract In hamsters, play fighting matures gradually into adult aggression. As these two behaviors share many similarities in this species, we predicted that…”
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Nitric oxide and protein phosphatase 2A provide novel therapeutic opportunities in ER-negative breast cancer by Switzer, Christopher H, Glynn, Sharon A, Ridnour, Lisa A, Cheng, Robert Y.-S, Vitek, Michael P, Ambs, Stefan, Wink, David A

“…Basal-like breast cancer is an aggressive disease with limited therapeutic options because these tumors frequently express the ‘triple-negative’ phenotype. We…”
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How much have electricity shortages hampered China's GDP growth? by Cheng, Y.S., Wong, W.K., Woo, C.K.

“…Based on an econometric analysis of the annual growth data for China's GDP and electricity generation from 1953 to 2010, we find that electricity generation…”
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The serum vitamin D metabolome: What we know and what is still to discover by Tuckey, Robert C., Cheng, Chloe Y.S., Slominski, Andrzej T.

“…[Display omitted] •The serum vitamin D metabolome has expanded substantially in recent years.•Several metabolites can be quantitated simultaneously by…”
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