Search Results - "Cheng, Lingge"

Remodeling the homeostasis of pro- and anti-angiogenic factors by Shenmai injection to normalize tumor vasculature for enhanced cancer chemotherapy by Cheng, Lingge, Liu, Wenyue, Zhong, Chongjin, Ni, Ping, Ni, Suiying, Wang, Qizhi, Zhang, Qixiang, Zhang, Jingwei, Liu, Jiali, Xu, Meijuan, Yao, Xuequan, Cen, Xiaobo, Wang, Guangji, Jiang, Chao, Zhou, Fang

“…Normalization of the tumor vasculature can enhance tumor perfusion and the microenvironment, leading to chemotherapy potentiation. Shenmai injection (SMI) is a…”
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Bevacizumab‐enhanced antitumor effect of 5‐fluorouracil via upregulation of thymidine phosphorylase through vascular endothelial growth factor A/vascular endothelial growth factor receptor 2‐specificity protein 1 pathway by Liu, Wenyue, Zhang, Jingwei, Yao, Xuequan, Jiang, Chao, Ni, Ping, Cheng, Lingge, Liu, Jiali, Ni, Suiying, Chen, Qianying, Li, Qingran, Zhou, Kai, Wang, Guangji, Zhou, Fang

“…Bevacizumab (Bv) can be used synergistically with fluoropyrimidine‐based chemotherapy to treat colorectal cancer. Whether and how it affects the delivery of…”
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Identification of bioactive anti-angiogenic components targeting tumor endothelial cells in Shenmai injection using multidimensional pharmacokinetics by Zhong, Chongjin, Jiang, Chao, Ni, Suiying, Wang, Qizhi, Cheng, Lingge, Wang, Huan, Zhang, Qixiang, Liu, Wenyue, Zhang, Jingwei, Liu, Jiali, Wang, Mulan, Jin, Min, Shen, Peiqiang, Yao, Xuequan, Wang, Guangji, Zhou, Fang

“…Shenmai injection (SMI) is a well-defined herbal preparation that is widely and clinically used as an adjuvant therapy for cancer. Previously, we found that…”
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Targeting tumor endothelial hyperglycolysis enhances immunotherapy through remodeling tumor microenvironment by Shan, Yunlong, Ni, Qi, Zhang, Qixiang, Zhang, Mengying, Wei, Bin, Cheng, Lingge, Zhong, Chongjin, Wang, Xinyu, Wang, Qingqing, Liu, Jiali, Zhang, Jingwei, Wu, Jingjing, Wang, Guangji, Zhou, Fang

“…Vascular abnormality is a hallmark of most solid tumors and facilitates immune evasion. Targeting the abnormal metabolism of tumor endothelial cells (TECs) may…”
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P1406: SAFETY AND EFFICACY OF IBI346, A FIRST‐IN‐CLASS BCMA‐TARGETING MODULAR CAR‐T CELL THERAPY, FOR PATIENTS WITH RELAPSED/REFRACTORY MULTIPLE MYELOMA (RRMM): PRELIMINARY RESULTS FROM TWO PHASE I STUDIES by Fu, Chengcheng, LI, Chunrui, Wang, DI, Jin, Song, Yao, Weiqin, Shang, Jingjing, Yan, Shuang, Xiao, Min, Chen, Liting, LI, Miao, Wei, Huafeng, Duo, Jia, Cheng, Lingge, Luo, Nana, Sui, Yongfang, Xu, Dan, Yang, Chunyan, Zhu, Lin, Klein, Christian, Wu, Depei

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Potent covalent irreversible inhibitor of KRAS G12C IBI351 in patients with advanced solid tumors: First-in-human phase I study by Zhou, Qing, Yang, Nong, Zhao, Mingfang, Huang, Dingzhi, Zhao, Jun, Yu, Yan, Yuan, Ying, Sun, Longhua, Dong, Xiaorong, Zhang, Tongmei, Chu, Qian, Li, Xingya, Meng, Xiangjiao, Wang, Huijuan, Wang, Xiang, Wu, Dongde, Hu, Sheng, Shan, Jinlu, Liu, Lian, Sun, Meili, Zhang, Zhiye, Zhu, Haibo, Huang, Jingjing, Huang, Mengna, Cheng, Lingge, Zhang, Sujie, Zhou, Hui, Wu, Yi-Long

“…IBI351 is an irreversible and covalent inhibitor of KRAS G12C. Despite FDA approval of two KRAS G12C inhibitors, there are still significant unmet clinical…”
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Study of the mass balance, biotransformation, and safety of [ 14 C]IBI351 in healthy Chinese subjects by Wang, Shuaishuai, Lin, Wen, Ahmed, Bilal, Zhong, Tianqi, Zhao, Jun, Xie, Lijun, Feng, Hao, Chen, Juan, Zhang, Chen, Yan, Peng, Zheng, Shirui, Cheng, Lingge, Cheng, Yipeng, Zhu, Bei, Han, Feng, Zhang, Lulu, Zhou, Chen

“…IBI351, a synthetic compound, exerts its anti-tumor effects by specifically, covalently, and irreversibly modifying the 12th cysteine residue of KRAS G12C…”
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Study of the mass balance, biotransformation, and safety of 14CIBI351 in healthy Chinese subjects by Wang, Shuaishuai, Lin, Wen, Ahmed, Bilal, Zhong, Tianqi, Zhao, Jun, Xie, Lijun, Feng, Hao, Chen, Juan, Zhang, Chen, Yan, Peng, Zheng, Shirui, Cheng, Lingge, Cheng, Yipeng, Zhu, Bei, Han, Feng, Zhang, Lulu, Zhou, Chen

“…IBI351, a synthetic compound, exerts its anti-tumor effects by specifically, covalently, and irreversibly modifying the 12th cysteine residue of KRAS G12C…”
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