Search Results - "Cheng, L. T"
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A meta-epidemiological study on the reported treatment effect of pregabalin in neuropathic pain trials over time
Published in PloS one (20-01-2023)“…Pregabalin is a drug used to treat neuropathic pain, and its use has increased substantially since 2007. Early trials found a strong treatment effect on pain…”
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2
Dewetting-controlled binding of ligands to hydrophobic pockets
Published in Physical review letters (30-10-2009)“…We report on a combined atomistic molecular dynamics simulation and implicit solvent analysis of a generic hydrophobic pocket-ligand (host-guest) system. The…”
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3
Investigating Effects of Mentoring for Youth with Assault Injuries: Results of a Randomized-Controlled Trial
Published in Prevention science (01-11-2022)“…Mentoring is considered an evidence-based practice for violence prevention. This study presents a partial replication of the Take Charge! program implemented…”
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4
Circulating tumor cells as a surrogate marker for determining clinical outcome to mFOLFOX chemotherapy in patients with stage III colon cancer
Published in British journal of cancer (05-03-2013)“…Background: This study was aimed to detect post-chemotherapeutic circulating tumour cells (CTCs) in stage III colon cancer patients and identify those who were…”
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Comparison of cryobiopsy and forceps biopsy for the diagnosis of mediastinal lesions: A randomised clinical trial
Published in Pulmonology (01-09-2024)“…Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is the standard approach for lung cancer staging. However, its diagnostic utility…”
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A Prospective Study of the Incidence of Juvenile-Onset Recurrent Respiratory Papillomatosis After Implementation of a National HPV Vaccination Program
Published in The Journal of infectious diseases (04-01-2018)“…Australian surveillance data document for the first time a significant decline in the incidence of juvenile-onset recurrent respiratory papillomatosis after a…”
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7
Induction of periosteal bone formation by intraosseous BMP-2 injection in a mouse model of osteogenesis imperfecta
Published in Journal of children's orthopaedics (01-10-2019)“…Abstract Purpose Surgical interventions are routinely performed on children with osteogenesis imperfecta (OI) to stabilize long bones, often post fracture. We…”
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8
Level set simulations of dislocation-particle bypass mechanisms
Published in Acta materialia (01-04-2004)“…Particle dispersions strengthen metals by acting as barriers to the motion of dislocations. A full analysis of the mechanisms by which dislocations bypass…”
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9
Approaches for Optimizing the First Electronic Hyperpolarizability of Conjugated Organic Molecules
Published in Science (American Association for the Advancement of Science) (05-04-1991)“…A two-state, four-orbital, independent electron analysis of the first optical molecular hyperpolarizability, β, leads to the prediction that |β| maximizes at a…”
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10
An integrated inventory model involving manufacturing setup cost reduction in compound Poisson process
Published in International journal of production research (15-02-2011)“…The collaboration of vendor and buyer is one of the key factors for successful supply chain management. The most common strategy for a cooperative system is to…”
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11
A Second-Order-Accurate Symmetric Discretization of the Poisson Equation on Irregular Domains
Published in Journal of computational physics (10-02-2002)“…In this paper, we consider the variable coefficient Poisson equation with Dirichlet boundary conditions on an irregular domain and show that one can obtain…”
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12
A sugar-based phase-transitioning delivery system for bone tissue engineering
Published in European cells & materials (22-10-2013)“…Bone tissue engineering approaches commonly involve the delivery of recombinant human bone morphogenetic proteins (rhBMPs). However, there are limitations…”
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13
The combination of the prodrugs perforin-CEBPD and perforin-granzyme B efficiently enhances the activation of caspase signaling and kills prostate cancer
Published in Cell death & disease (08-05-2014)“…The survival of prostate cancer (PrCa) patients is associated with the transition to hormone-independent tumor growth and metastasis. Clinically, the…”
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14
Tumor-targeting prodrug-activating bacteria for cancer therapy
Published in Cancer gene therapy (01-06-2008)“…Increasing the specificity of chemotherapy may improve the efficacy of cancer treatment. Toward this aim, we developed a strain of bacteria to express enzymes…”
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Enhancement of CPT-11 antitumor activity by adenovirus-mediated expression of β-glucuronidase in tumors
Published in Cancer gene therapy (01-06-2011)“…CPT-11 is a clinically important prodrug that requires conversion into the active metabolite SN-38, a potent topoisomerase I poison, for antitumor activity…”
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16
Visibility and its dynamics in a PDE based implicit framework
Published in Journal of computational physics (01-09-2004)“…We investigate the problem of determining visible regions given a set of (moving) obstacles and a (moving) vantage point. Our approach to this problem is…”
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17
Overview of injuries in the young athlete
Published in Sports medicine (Auckland) (2003)“…It is estimated that 30 million children in the US participate in organised sports programmes. As more and more children participate in sports and recreational…”
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18
Distraction osteogenesis and glossopexy for Robin sequence with airway obstruction
Published in ANZ journal of surgery (01-05-2011)“…Background: We present six cases of infants with Robin sequence and severe obstructive sleep apnoea who failed treatment with nasal mask continuous positive…”
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Expression of β-glucuronidase on the surface of bacteria enhances activation of glucuronide prodrugs
Published in Cancer gene therapy (01-05-2013)“…Extracellular activation of hydrophilic glucuronide prodrugs by β-glucuronidase (βG) was examined to increase the therapeutic efficacy of bacteria-directed…”
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20
Juvenile recurrent respiratory papillomatosis: 10-year audit and Australian prevalence estimates
Published in The Laryngoscope (01-12-2016)“…Objectives/Hypothesis To estimate the prevalence of juvenile onset recurrent respiratory papillomatosis (RRP) in Australia, describe its epidemiological…”
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