Search Results - "Cheng, Keding"

Recent development of mass spectrometry and proteomics applications in identification and typing of bacteria by Cheng, Keding, Chui, Huixia, Domish, Larissa, Hernandez, Drexler, Wang, Gehua

“…Identification and typing of bacteria occupy a large fraction of time and work in clinical microbiology laboratories. With the certification of some MS…”
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Cerebrospinal fluid real-time quaking-induced conversion is a robust and reliable test for sporadic creutzfeldt-jakob disease: An international study by McGuire, Lynne I., Poleggi, Anna, Poggiolini, Ilaria, Suardi, Silvia, Grznarova, Katarina, Shi, Song, de Vil, Bart, Sarros, Shannon, Satoh, Katsuya, Cheng, Keding, Cramm, Maria, Fairfoul, Graham, Schmitz, Matthias, Zerr, Inga, Cras, Patrick, Equestre, Michele, Tagliavini, Fabrizio, Atarashi, Ryuichiro, Knox, David, Collins, Steven, Haïk, Stéphane, Parchi, Piero, Pocchiari, Maurizio, Green, Alison

“…Real‐time quaking‐induced conversion (RT‐QuIC) has been proposed as a sensitive diagnostic test for sporadic Creutzfeldt–Jakob disease; however, before this…”
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Naturally Occurring Single Mutations in Ebola Virus Observably Impact Infectivity by Wong, Gary, He, Shihua, Leung, Anders, Cao, Wenguang, Bi, Yuhai, Zhang, Zirui, Zhu, Wenjun, Wang, Liang, Zhao, Yuhui, Cheng, Keding, Liu, Di, Liu, Wenjun, Kobasa, Darwyn, Gao, George F, Qiu, Xiangguo

“…Sequencing of Ebola virus (EBOV) genomes during the 2014-2016 epidemic identified several naturally occurring, dominant mutations potentially impacting…”
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Incorporation of Ebola glycoprotein into HIV particles facilitates dendritic cell and macrophage targeting and enhances HIV-specific immune responses by Ao, Zhujun, Wang, Lijun, Mendoza, Emelissa J, Cheng, Keding, Zhu, Wenjun, Cohen, Eric A, Fowke, Keith, Qiu, Xiangguo, Kobinger, Gary, Yao, Xiaojian

“…The development of an effective vaccine against HIV infection remains a global priority. Dendritic cell (DC)-based HIV immunotherapeutic vaccine is a promising…”
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Atypical Ebola Virus Disease in a Nonhuman Primate following Monoclonal Antibody Treatment Is Associated with Glycoprotein Mutations within the Fusion Loop by Banadyga, Logan, Zhu, Wenjun, Kailasan, Shweta, Howell, Katie A, Franaszek, Krzysztof, He, Shihua, Siragam, Vinayakumar, Cheng, Keding, Yan, Feihu, Moffat, Estella, Cao, Wenguang, Leung, Anders, Embury-Hyatt, Carissa, Aman, M Javad, Qiu, Xiangguo

“…Ebola virus (EBOV) is responsible for numerous devastating outbreaks throughout Africa, including the 2013-2016 West African outbreak as well as the two recent…”
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Exploring physical and chemical factors influencing the properties of recombinant prion protein and the real-time quaking-induced conversion (RT-QuIC) assay by Cheng, Keding, Sloan, Angela, Avery, Kristen M, Coulthart, Michael, Carpenter, Michael, Knox, J David

“…Real-time quaking-induced conversion (RT-QuIC), a highly specific and sensitive assay able to detect low levels of the disease-inducing isoform of the prion…”
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The role of angiotensin converting enzyme 2 in the generation of angiotensin 1-7 by rat proximal tubules by Li, Ningjun, Zimpelmann, Joseph, Cheng, Keding, Wilkins, John A, Burns, Kevin D

“…ANG converting enzyme (ACE) 2 (ACE2) is a homologue of ACE, which is not blocked by conventional ACE inhibitors. ACE2 converts ANG 1-10 (ANG I) to ANG 1-9,…”
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MS-H: a novel proteomic approach to isolate and type the E. coli H antigen using membrane filtration and liquid chromatography-tandem mass spectrometry (LC-MS/MS) by Cheng, Keding, Drebot, Mike, McCrea, Joanne, Peterson, Lorea, Lee, David, McCorrister, Stuart, Nickel, Richard, Gerbasi, Alyssia, Sloan, Angela, Janella, Debra, Van Domselaar, Gary, Beniac, Daniel, Booth, Tim, Chui, Linda, Tabor, Helen, Westmacott, Garrett, Gilmour, Matthew, Wang, Gehua

“…Serotyping is the long-standing gold standard method to determine E. coli H antigens; however, this method requires a panel of H-antigen specific antibodies…”
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Traditional approaches versus mass spectrometry in bacterial identification and typing by Sloan, Angela, Wang, Gehua, Cheng, Keding

“…Biochemical methods such as metabolite testing and serotyping are traditionally used in clinical microbiology laboratories to identify and categorize…”
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Evidence for the presence of a low-mass β1 integrin on the cell surface by Meng, Xiaobo, Cheng, Keding, Krohkin, Oleg, Mould, A. Paul, Humphries, Martin J., Ens, Werner, Standing, Kenneth, Wilkins, John A.

“…Although the cell line K562 reportedly expresses a single species of β1 integrin, α5β1, surface staining with monoclonal antibodies JB1A, 12G10 and B3B11 to…”
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Device for the Reversed-Phase Separation and On-Target Deposition of Peptides Incorporating a Hydrophobic Sample Barrier for Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry by Chen, Vincent C, Cheng, Keding, Ens, Werner, Standing, Kenneth G, Nagy, James I, Perreault, Hélène

“…The separation of peptide mixtures from proteolytic cleavage is often necessary prior to mass spectrometry (MS) to enhance sensitivity and peptide mapping…”
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An online monitoring system for atmospheric nitrous acid （HONO） based on stripping coil and ion chromatography by Peng Cheng Yafang Cheng Keding Lu Hang Su Qiang Yang Yikan Zou Yanran Zhao Huabing Dong Limin Zeng Yuanhang Zhang

“…A new instrument for measuring atmospheric nitrous acid（HONO） was developed,consisting of a double-wall glass stripping coil sampler coupled with ion…”
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Reduced focal adhesion kinase and paxillin phosphorylation in BCR‐ABL‐transfected cells by Cheng, Keding, Kurzrock, Razelle, Qiu, Xiangguo, Estrov, Zeev, Ku, Stella, Dulski, Kim M., Wang, Jean Y. J., Talpaz, Moshe

“…BACKGROUND BCR‐ABL formation is critical to oncogenic transformation in chronic myelogenous leukemia and has been implicated as a key event leading to…”
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ThermoMixer-Aided Endpoint Quaking-Induced Conversion (EP-QuIC) Permits Faster Sporadic Creutzfeldt-Jakob Disease (sCJD) Identification than Real-Time Quaking-Induced Conversion (RT-QuIC) by Vendramelli, Robert, Sloan, Angela, Simon, Sharon L R, Godal, Debra, Cheng, Keding

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Mass spectrometry-based Shiga toxin identification: An optimized approach by Cheng, Keding, Sloan, Angela, Li, Xingle, Armstrong, Glen D., Wang, Gehua

“…Toxin expression is a key factor in Shiga toxin (Stx)-producing E. coli, a common pathogen involved in foodborne disease outbreaks. A liquid…”
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Endpoint Quaking-Induced Conversion: a Sensitive, Specific, and High-Throughput Method for Antemortem Diagnosis of Creutzfeldt-Jacob Disease by Cheng, Keding, Vendramelli, Robert, Sloan, Angela, Waitt, Brooks, Podhorodecki, Lisa, Godal, Debra, Knox, J David

“…The Prion Laboratory Section of the Public Health Agency of Canada supports heath care professionals dealing with patients suspected to have Creutzfeldt-Jakob…”
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Mass Spectrometric Characterization of Proteins from the SARS Virus by Krokhin, Oleg, Li, Yan, Andonov, Anton, Feldmann, Heinz, Flick, Ramon, Jones, Steven, Stroeher, Ute, Bastien, Nathalie, Dasuri, Kumar V.N., Cheng, Keding, Simonsen, J. Neil, Perreault, Hélène, Wilkins, John, Ens, Werner, Plummer, Frank, Standing, Kenneth G.

“…A new coronavirus has been implicated as the causative agent of severe acute respiratory syndrome (SARS). We have used convalescent sera from several SARS…”
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Surface modifications of influenza proteins upon virus inactivation by β-propiolactone by She, Yi-Min, Cheng, Keding, Farnsworth, Aaron, Li, Xuguang, Cyr, Terry D.

“…Inactivation of intact influenza viruses using formaldehyde or β‐propiolactone (BPL) is essential for vaccine production and safety. The extent of chemical…”
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Equine-Origin Immunoglobulin Fragments Protect Nonhuman Primates from Ebola Virus Disease by Wang, Hualei, Wong, Gary, Zhu, Wenjun, He, Shihua, Zhao, Yongkun, Yan, Feihu, Rahim, Md Niaz, Bi, Yuhai, Zhang, Zirui, Cheng, Keding, Jin, Hongli, Cao, Zengguo, Zheng, Xuexing, Gai, Weiwei, Bai, Jieying, Chen, Weijin, Zou, Yong, Gao, Yuwei, Gao, George F, Yang, Songtao, Xia, Xianzhu, Qiu, Xiangguo

“…Ebola virus (EBOV) infections result in aggressive hemorrhagic fever in humans, with fatality rates reaching 90% and with no licensed specific therapeutics to…”
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Rapid, Sensitive, and Specific Escherichia coli H Antigen Typing by Matrix-Assisted Laser Desorption Ionization-Time of Flight-Based Peptide Mass Fingerprinting by Chui, Huixia, Chan, Michael, Hernandez, Drexler, Chong, Patrick, McCorrister, Stuart, Robinson, Alyssia, Walker, Matthew, Peterson, Lorea A M, Ratnam, Sam, Haldane, David J M, Bekal, Sadjia, Wylie, John, Chui, Linda, Westmacott, Garrett, Xu, Bianli, Drebot, Mike, Nadon, Celine, Knox, J David, Wang, Gehua, Cheng, Keding

“…Matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) has gained popularity in recent years for rapid bacterial…”
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