Search Results - "Cheng, Jianding"
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Forensic Pathological Study of 1656 Cases of Sudden Cardiac Death in Southern China
Published in Medicine (Baltimore) (01-02-2016)“…Sudden cardiac death (SCD) is progressively threatening the lives of young people throughout the world. We conducted a retrospective study of SCD cases…”
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2
Retinol dehydrogenase 10 reduction mediated retinol metabolism disorder promotes diabetic cardiomyopathy in male mice
Published in Nature communications (02-03-2023)“…Diabetic cardiomyopathy is a primary myocardial injury induced by diabetes with complex pathogenesis. In this study, we identify disordered cardiac retinol…”
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3
Mechanosensitive Piezo1 channels mediate renal fibrosis
Published in JCI insight (08-04-2022)“…Kidney fibrosis is the final common pathway of progressive kidney diseases, the underlying mechanisms of which are not fully understood. The purpose of the…”
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4
Distinct cardiac energy metabolism and oxidative stress adaptations between obese and non-obese type 2 diabetes mellitus
Published in Theranostics (01-01-2020)“…: Little is known about the pathophysiological diversity of myocardial injury in type 2 diabetes mellitus (T2DM), but analyzing these differences is important…”
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5
Analysis of false-positive results of diatom test in the diagnosis of drowning—would not be an impediment
Published in International journal of legal medicine (01-11-2019)“…Diatom test has been a significant tool for the diagnosis of drowning. The reliability of the diatom test is still in strong dispute in the field of forensic…”
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Does Sudden Unexplained Nocturnal Death Syndrome Remain the Autopsy-Negative Disorder: A Gross, Microscopic, and Molecular Autopsy Investigation in Southern China
Published in Mayo Clinic proceedings (01-11-2016)“…Abstract Objective To look for previously unrecognized cardiac structural abnormalities and address the genetic cause for sudden unexplained nocturnal death…”
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7
Transcription factor Hoxb5 reveals the unidirectional hierarchy of hematopoietic stem cell pool
Published in Stem cell research (01-04-2024)“…[Display omitted] •Construction of a Hoxb5 knockout reporter mouse model at the HSC level for the first time.•In the primary recipients, depletion of Hoxb5 in…”
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Sudden Unexplained Nocturnal Death Syndrome: The Hundred Years' Enigma
Published in Journal of the American Heart Association (06-03-2018)Get full text
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Ursolic acid simultaneously targets multiple signaling pathways to suppress proliferation and induce apoptosis in colon cancer cells
Published in PloS one (30-05-2013)“…Ursolic acid (UA), a natural pentacyclic triterpenoid carboxylic acid distributed in medical herbs, exerts antitumor effects and is emerging as a promising…”
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Loss of Endothelial Hypoxia Inducible Factor-Prolyl Hydroxylase 2 Induces Cardiac Hypertrophy and Fibrosis
Published in Journal of the American Heart Association (16-11-2021)“…Background Cardiac hypertrophy and fibrosis are common adaptive responses to injury and stress, eventually leading to heart failure. Hypoxia signaling is…”
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Investigation of the Application of miR10b and miR135b in the Identification of Semen Stains
Published in PloS one (10-09-2015)“…To evaluate the identification method using the microRNA markers miR10b and miR135b to distinguish semen stains from menstrual blood, peripheral blood, vaginal…”
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Sudden Cardiac Death and Cardiac Sodium Channel Diseases
Published in Journal of forensic science and medicine (01-10-2022)“…Sudden cardiac death (SCD), accounting for a substantial part of the forensic autopsy, is a leading cause of mortality worldwide. Lethal arrhythmia due to…”
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13
The biophysical characterization of the first SCN5A mutation R1512W identified in Chinese sudden unexplained nocturnal death syndrome
Published in Medicine (Baltimore) (01-06-2016)“…Increasing evidence observed in clinical phenotypes show that abrupt breathing disorders during sleep may play an important role in the pathogenesis of sudden…”
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The characteristics of thoracic aortic dissection in autopsy-diagnosed individuals: An autopsy study
Published in Frontiers in cardiovascular medicine (11-10-2022)“…Thoracic aortic dissection (TAD) is the most common cause of sudden cardiac death associated with aortic diseases. The age of TAD victims in forensic studies…”
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Characteristics of Mechanical Asphyxia: A Retrospective Epidemiological Study in Two Developed Cities in China
Published in Journal of forensic science and medicine (01-01-2023)“…Background: Mechanical asphyxia (MA) is multi-classified. Some epidemiological characteristics are shared and the others different among different MA types…”
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α1-Syntrophin Mutations Identified in Sudden Infant Death Syndrome Cause an Increase in Late Cardiac Sodium Current
Published in Circulation. Arrhythmia and electrophysiology (01-12-2009)“…BACKGROUND—Sudden infant death syndrome (SIDS) is a leading cause of death during the first 6 months after birth. About 5% to 10% of SIDS may stem from cardiac…”
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Correlation analysis of diatom content in the organs and drowning mediums for the drowning death cases
Published in Australian journal of forensic sciences (04-03-2021)“…Diatoms detected in human organs have been considered as supportive evidence for the diagnosis of drowning. During drowning, the vast majority of diatoms are…”
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Critical Roles of Xirp Proteins in Cardiac Conduction and Their Rare Variants Identified in Sudden Unexplained Nocturnal Death Syndrome and Brugada Syndrome in Chinese Han Population
Published in Journal of the American Heart Association (06-01-2018)“…Background Sudden unexplained nocturnal death syndrome (SUNDS) remains an autopsy negative entity with unclear etiology. Arrhythmia has been implicated in…”
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Does Anatomic Phenotype of Mitral Annular Disjunction Impact Survival? An Autopsy-Based Retrospective Study
Published in Journal of cardiovascular development and disease (05-12-2021)“…Controversies have been raised regarding the prevalence and potential clinical significance of mitral annular disjunction (MAD). We aim to address the anatomic…”
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Detection of the deletion on Yp11.2 in a Chinese population
Published in Forensic science international : genetics (01-01-2014)“…Abstract Sex determination tests based on Amelogenin gene as part of commercial PCR multiplex reaction kits have been widely applied in forensic DNA analysis…”
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