Search Results - "Cheng, Dayna"
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Enterovirus A71: virulence, antigenicity, and genetic evolution over the years
Published in Journal of biomedical science (21-10-2019)“…As a neurotropic virus, enterovirus A71 (EV-A71) emerge and remerge in the Asia-Pacific region since the 1990s, and has continuously been a threat to global…”
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The molecular epidemiology of a dengue virus outbreak in Taiwan: population wide versus infrapopulation mutation analysis
Published in PLoS neglected tropical diseases (13-06-2024)“…Dengue virus (DENV) causes approximately 390 million dengue infections worldwide every year. There were 22,777 reported DENV infections in Tainan, Taiwan in…”
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Serological responses triggered by different SARS-CoV-2 vaccines against SARS-CoV-2 variants in Taiwan
Published in Frontiers in immunology (15-11-2022)“…Broadly neutralizing ability is critical for developing the next-generation SARS-CoV-2 vaccine. We collected sera samples between December 2021-January 2022…”
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Impact of Intrahost NS5 Nucleotide Variations on Dengue Virus Replication
Published in Frontiers in microbiology (05-07-2022)“…Due to the nature of RNA viruses, their high mutation rates produce a population of closely related but genetically diverse viruses, termed quasispecies. To…”
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Investigation of Avian Influenza H5N6 Virus-like Particles as a Broad-Spectrum Vaccine Candidate against H5Nx Viruses
Published in Viruses (28-04-2022)“…Highly pathogenic avian influenza (HPAI) clade 2.3.4.4 viruses have been reported to be the source of infections in several outbreaks in the past decades. In a…”
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Conserved Residues Adjacent to ß-Barrel and Loop Intersection among Enterovirus VP1 Affect Viral Replication: Potential Target for Anti-Enteroviral Development
Published in Viruses (10-02-2022)“…genus has over one hundred genotypes and could cause several kinds of severe animal and human diseases. Understanding the role of conserved residues in the VP1…”
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Genetic and Cross Neutralization Analyses of Coxsackievirus A16 Circulating in Taiwan from 1998 to 2021 Suggest Dominant Genotype B1 can Serve as Vaccine Candidate
Published in Viruses (01-10-2022)“…Coxsackievirus A16 (CVA16) is well known for causing hand-foot-and-mouth disease (HFMD) and outbreaks were frequently reported in Taiwan in the past twenty…”
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Assessing the application of a pseudovirus system for emerging SARS-CoV-2 and re-emerging avian influenza virus H5 subtypes in vaccine development
Published in Biomedical Journal (01-08-2020)“…Highly pathogenic emerging and re-emerging viruses continuously threaten lives worldwide. In order to provide prophylactic prevention from the emerging and…”
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Antigenic mapping of enterovirus A71 from Taiwan and Southeast Asia
Published in Antiviral research (01-04-2023)“…Enterovirus A71 (EV-A71) is a non-enveloped virus possessing 4 capsid proteins: VP1-VP4. The outermost capsid protein, VP1, plays roles in both antigenicity…”
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VP1 codon deoptimization and high-fidelity substitutions in 3D polymerase as potential vaccine strategies for eliciting immune responses against enterovirus A71
Published in Journal of virology (23-01-2024)“…Enterovirus A71 (EV-A71) can induce severe neurological complications and even fatal encephalitis in children, and it has caused several large outbreaks in…”
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