Search Results - "Chen-lo H. Chen"

Chicken cathelicidin-B1, an antimicrobial guardian at the mucosal M cell gateway by Goitsuka, Ryo, Chen, Chen-lo H, Benyon, Lesley, Asano, Yusuke, Kitamura, Daisuke, Cooper, Max D

“…Mucosal epithelial M cells provide an efficient portal of entry for microorganisms. Initially defined by their irregular microvilli and abundant transcytotic…”
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T Cell Receptor Gene Deletion Circles Identify Recent Thymic Emigrants in the Peripheral T Cell Pool by Kong, Fan-kun, Chen-lo H. Chen, Six, Adrien, Hockett, Richard D., Cooper, Max D.

“…Progenitor cells undergo T cell receptor (TCR) gene rearrangements during their intrathymic differentiation to become T cells. Rearrangements of the variable…”
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Reversible Disruption of Thymic Function by Steroid Treatment by Kong, Fan-kun, Chen, Chen-lo H, Cooper, Max D

“…The effect of steroid treatment on the thymic output of T cells was examined in an avian model. Recent thymic emigrants in chickens transiently express the…”
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Thymic Function Can Be Accurately Monitored by the Level of Recent T Cell Emigrants in the Circulation by Kong, Fan-kun, Chen, Chen-lo H., Cooper, Max D.

“…Expression of the avian chT1 thymocyte antigen persists on a subpopulation of peripheral T cells enriched in the DNA deletion circles created by αβ and γδ TCR…”
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Characterization of avian T-cell receptor gamma genes by Six, A. (University of Alabama, Birmingham, AL.), Rast, J.P, McCormack, W.T, Dunon, D, Courtois, D, Li, Y, Chen, C.H, Cooper, M.D

“…In birds and mammals T cells develop along two discrete pathways characterized by expression of either the alpha beta or the gamma delta T-cell antigen…”
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Characterization of an Avian (Gallus gallus domesticus) TCR {alpha}{delta} Gene Locus by Kubota, Takayuki, Wang, Jin-yi, Gobel, Thomas W. F, Hockett, Richard D, Cooper, Max D, Chen, Chen-lo H

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Evolution of T cell receptor (TCR) α β  heterodimer assembly with the CD3 complex by Gouaillard, Cécile, Huchenq‐Champagne, Anne, Arnaud, Jacques, Chen, Chen‐lo H., Rubin, Bent

“…T cell antigen receptors (TCR) are composed of an antigen‐recognizing unit, the TCRα β  heterodimer, and a signal transduction ensemble, the CD3 complex…”
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A novel avian homologue of CD72, chB1r, down modulates BCR-mediated activation signals by Fujiwara, Naruyoshi, Hidano, Shinya, Mamada, Hiroshi, Ogasawara, Koetsu, Kitamura, Daisuke, Cooper, Max D, Hozumi, Nobumichi, Chen, Chen-Lo H, Goitsuka, Ryo

“…The avian B cell differentiation antigen chB1 is a C-type lectin membrane protein most homologous to mammalian CD72. Here, we report a new chB1-related gene,…”
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Catfish Thrombocytes Express an Integrin-like CD41/CD61 Complex by Passer, Brent J., Chen, Chen-lo H., Miller, Norman W., Cooper, Max D.

“…A thrombocyte-specific antigen was identified in two closely related catfish,Ictalurus punctatusandIctalurus furcatus,by monoclonal antibodies 4-20 and 7-2…”
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Characterization of avian natural killer cells and their intracellular CD3 protein complex by Göbel, T W, Chen, C L, Shrimpf, J, Grossi, C E, Bernot, A, Bucy, R P, Auffray, C, Cooper, M D

“…Natural killer (NK) cell activity appears to be conserved throughout vertebrate development but NK cells have only been well characterized in mammals…”
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B cells in the bursa of Fabricius express a novel C-type lectin gene by Goitsuka, R, Chen, CH, Cooper, MD

“…The avian bursa of Fabricius provides an essential microenvironment for B cell development and Ab repertoire expansion by a gene conversion mechanism. To…”
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Identification of T-cell receptor alpha-chain genes in the chicken by Gobel, T.W.F, Chen, C.L.H, Lahti, J, Kubota, T, Kuo, C.L, Aebersold, R, Hood, L, Cooper, M.D

“…T-cell receptor (TCR) alpha-chain (TCR alpha) and beta-chain (TCR beta) genes are well characterized in mammals, while only TCR beta genes have been identified…”
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Evolutionary Conservation of Antigen Recognition: The Chicken T-Cell Receptor β Chain by Tjoelker, Larry W., Carlson, Louise M., Lee, Kelvin, Lahti, Jill, McCormack, Wayne T., Leiden, Jeffrey M., Chen-Lo H. Chen, Cooper, Max D., Thompson, Craig B.

“…T cells play important regulatory roles in the immune responses of vertebrates. Antigen-specific T-cell activation involves T-cell receptor (TCR) recognition…”
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Characterization of an Avian ( Gallus gallus domesticus ) TCR αδ Gene Locus by Kubota, Takayuki, Wang, Jin-yi, Göbel, Thomas W. F., Hockett, Richard D., Cooper, Max D., Chen, Chen-lo H.

“…Abstract Mammalian TCRδ genes are located in the midst of the TCRα gene locus. In the chicken, one large Vδ gene family, two Dδ gene segments, two Jδ gene…”
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Differential regulation of V(D)J recombination during development of avian B and T cells by Pickel, J M, McCormack, W T, Chen, C H, Cooper, M D, Thompson, C B

“…The lymphoid immune system is comprised of two major cell types, B cells and T cells, originally identified in avian species. Although both lineages arise from…”
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Genomic Structure and Transcriptional Regulation of the Early B Cell Gene chB1 by Goitsuka, Ryo, Mamada, Hiroshi, Kitamura, Daisuke, Cooper, Max D, Chen2, Chen-lo H

“…The avian B cell differentiation Ag chB1 is a membrane glycoprotein relative of the mammalian B cell differentiation Ag CD72. Unlike CD72, this C-type lectin…”
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Characterization of an avian (Gallus gallus domesticus) TCR alpha delta gene locus by Kubota, T, Wang, J, Göbel, T W, Hockett, R D, Cooper, M D, Chen, C H

“…Mammalian TCR delta genes are located in the midst of the TCR alpha gene locus. In the chicken, one large V delta gene family, two D delta gene segments, two J…”
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Identification of A T lineage antigen in the catfish by Passer, Brent J., Chen, Chen-Io H., Miller, Norman W., Cooper, Max D.

“…A murine monoclonal antibody produced against catfish thymocytes and immunoglobulin-negative lymphocytes in the blood identified a catfish T cell antigen…”
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Ontogeny of T cell receptors in the chicken thymus by Bucy, R.P. (UAB Station, Birmingham, AL), Chen, C.H, Cooper, M.D

“…A panel of murine mAb against chicken TCR and associated molecules was used to study the ontogeny of T cells. The intrathymic maturation of the TCR-gamma…”
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A third sublineage of avian T cells can be identified with a T cell receptor-3-specific antibody by Char, D, Sanchez, P, Chen, CL, Bucy, RP, Cooper, MD

“…Avian homologues of mammalian gamma delta and alpha beta TCR, termed TCR1 and TCR2, have been identified in the chicken with specific mAb. A third TCR, dubbed…”
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