Search Results - "Chen Yongbin"

Apoptosis, autophagy, necroptosis, and cancer metastasis by Su, Zhenyi, Yang, Zuozhang, Xu, Yongqing, Chen, Yongbin, Yu, Qiang

“…Metastasis is a crucial hallmark of cancer progression, which involves numerous factors including the degradation of the extracellular matrix (ECM), the…”
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MicroRNAs in apoptosis, autophagy and necroptosis by Su, Zhenyi, Yang, Zuozhang, Xu, Yongqing, Chen, Yongbin, Yu, Qiang

“…MicroRNAs (miRNAs) are endogenous 22 nt non-coding RNAs that target mRNAs for cleavage or translational repression. Numerous miRNAs regulate programmed cell…”
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Decoding the phosphorylation code in Hedgehog signal transduction by Chen, Yongbin, Jiang, Jin

“…Hedgehog （Hh） signaling plays pivotal roles in embryonic development and adult tissue homeostasis, and its de-regulation leads to numerous human disorders…”
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Smoothened transduces Hedgehog signal by forming a complex with Evc/Evc2 by Yang, Cuiping, Chen, Wenlin, Chen, Yongbin, Jiang, Jin

“…Hedgehog （Hh） signaling plays pivotal roles in embryonic development and adult tissue homeostasis in species ranging from Drosophila to mammals. The Hh signal…”
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The role of m6A modification in the biological functions and diseases by Jiang, Xiulin, Liu, Baiyang, Nie, Zhi, Duan, Lincan, Xiong, Qiuxia, Jin, Zhixian, Yang, Cuiping, Chen, Yongbin

“…N 6 -methyladenosine (m6A) is the most prevalent, abundant and conserved internal cotranscriptional modification in eukaryotic RNAs, especially within higher…”
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YTHDF1 links hypoxia adaptation and non-small cell lung cancer progression by Shi, Yulin, Fan, Songqing, Wu, Mengge, Zuo, Zhixiang, Li, Xingyang, Jiang, Liping, Shen, Qiushuo, Xu, Peifang, Zeng, Lin, Zhou, Yongchun, Huang, Yunchao, Yang, Zuozhang, Zhou, Jumin, Gao, Jing, Zhou, Hu, Xu, Shuhua, Ji, Hongbin, Shi, Peng, Wu, Dong-Dong, Yang, Cuiping, Chen, Yongbin

“…Hypoxia occurs naturally at high-altitudes and pathologically in hypoxic solid tumors. Here, we report that genes involved in various human cancers evolved…”
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The TEAD/TEF Family of Transcription Factor Scalloped Mediates Hippo Signaling in Organ Size Control by Zhang, Lei, Ren, Fangfang, Zhang, Qing, Chen, Yongbin, Wang, Bing, Jiang, Jin

“…The Hippo (Hpo) signaling pathway governs cell growth, proliferation, and apoptosis by controlling key regulatory genes that execute these processes; however,…”
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LncRNA PKMYT1AR promotes cancer stem cell maintenance in non-small cell lung cancer via activating Wnt signaling pathway by He, Yaomei, Jiang, Xiulin, Duan, Lincan, Xiong, Qiuxia, Yuan, Yixiao, Liu, Peishen, Jiang, Liping, Shen, Qiushuo, Zhao, Song, Yang, Cuiping, Chen, Yongbin

“…Non-small cell lung cancer (NSCLC) is the most common type of human lung cancers, which has diverse pathological features. Although many signaling pathways and…”
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Separation and recovery of metal values from leach liquor of waste lithium nickel cobalt manganese oxide based cathodes by Chen, Xiangping, Zhou, Tao, Kong, Jiangrong, Fang, Huaxiong, Chen, Yongbin

“…•A combined hydro-metallurgical process has been proposed.•Nickle, cobalt and lithium were recovered by selective precipitation method.•Manganese was recovered…”
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The Effects of Audiovisual Inputs on Solving the Cocktail Party Problem in the Human Brain: An fMRI Study by Li, Yuanqing, Wang, Fangyi, Chen, Yongbin, Cichocki, Andrzej, Sejnowski, Terrence

“…Abstract At cocktail parties, our brains often simultaneously receive visual and auditory information. Although the cocktail party problem has been widely…”
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Sonic Hedgehog dependent phosphorylation by CK1α and GRK2 is required for ciliary accumulation and activation of smoothened by Chen, Yongbin, Sasai, Noriaki, Ma, Guoqiang, Yue, Tao, Jia, Jianhang, Briscoe, James, Jiang, Jin

“…Hedgehog (Hh) signaling regulates embryonic development and adult tissue homeostasis through the GPCR-like protein Smoothened (Smo), but how vertebrate Smo is…”
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Regulation of Smoothened Phosphorylation and High-Level Hedgehog Signaling Activity by a Plasma Membrane Associated Kinase by Li, Shuangxi, Li, Shuang, Han, Yuhong, Tong, Chao, Wang, Bing, Chen, Yongbin, Jiang, Jin

“…Hedgehog (Hh) signaling controls embryonic development and adult tissue homeostasis through the G protein coupled receptor (GPCR)-family protein Smoothened…”
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Mammalian Mst1 and Mst2 kinases play essential roles in organ size control and tumor suppression by Song, Hai, Mak, Kinglun Kingston, Topol, Lilia, Yun, Kangsun, Hu, Jianxin, Garrett, Lisa, Chen, Yongbin, Park, Ogyi, Chang, Jia, Simpson, R. Mark, Wang, Cun-Yu, Gao, Bin, Jiang, Jin, Yang, Yingzi

“…Control of organ size by cell proliferation and survival is a fundamental developmental process, and its deregulation leads to cancer. However, the molecular…”
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Replacement of saturated fatty acids with linoleic acid in western diet attenuates atherosclerosis in a mouse model with inducible ablation of hepatic LDL receptor by Burr, Stephanie D., Chen, Yongbin, Hartley, Christopher P., Zhao, Xianda, Liu, Jun

“…Dietary saturate fatty acids (SFAs) have been consistently linked to atherosclerosis and obesity, both of which are characterized by chronic inflammation and…”
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Comprehensive integrative analyses identify GLT8D1 and CSNK2B as schizophrenia risk genes by Yang, Cui-Ping, Li, Xiaoyan, Wu, Yong, Shen, Qiushuo, Zeng, Yong, Xiong, Qiuxia, Wei, Mengping, Chen, Chunhui, Liu, Jiewei, Huo, Yongxia, Li, Kaiqin, Xue, Gui, Yao, Yong-Gang, Zhang, Chen, Li, Ming, Chen, Yongbin, Luo, Xiong-Jian

“…Recent genome-wide association studies (GWAS) have identified multiple risk loci that show strong associations with schizophrenia. However, pinpointing the…”
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Hedgehog-regulated ubiquitination controls smoothened trafficking and cell surface expression in Drosophila by Li, Shuang, Chen, Yongbin, Shi, Qing, Yue, Tao, Wang, Bing, Jiang, Jin

“…Hedgehog transduces signal by promoting cell surface expression of the seven-transmembrane protein Smoothened (Smo) in Drosophila, but the underlying mechanism…”
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PNPLA3 is a triglyceride lipase that mobilizes polyunsaturated fatty acids to facilitate hepatic secretion of large-sized very low-density lipoprotein by Johnson, Scott M., Bao, Hanmei, McMahon, Cailin E., Chen, Yongbin, Burr, Stephanie D., Anderson, Aaron M., Madeyski-Bengtson, Katja, Lindén, Daniel, Han, Xianlin, Liu, Jun

“…The I148M variant of PNPLA3 is closely associated with hepatic steatosis. Recent evidence indicates that the I148M mutant functions as an inhibitor of…”
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Multiple Ser/Thr-rich degrons mediate the degradation of Ci/Gli by the Cul3-HIB/SPOP E3 ubiquitin ligase by Zhang, Qing, Shi, Qing, Chen, Yongbin, Yue, Tao, Li, Shuang, Wang, Bing, Jiang, Jin

“…The Cul3-based E3 ubiquitin ligases regulate many cellular processes using a large family of BTB domain-containing proteins as their target recognition…”
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Discriminative analysis of Parkinson's disease based on whole-brain functional connectivity by Chen, Yongbin, Yang, Wanqun, Long, Jinyi, Zhang, Yuhu, Feng, Jieying, Li, Yuanqing, Huang, Biao

“…Recently, there has been an increasing emphasis on applications of pattern recognition and neuroimaging techniques in the effective and accurate diagnosis of…”
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Effect of Mn/Ag Ratio on Microstructure and Mechanical Properties of Heat-Resistant Al-Cu Alloys by Fu, Xiangzhou, Yang, Hailong, Wang, Hanzhang, Huang, Chifu, Chen, Yongbin, Huang, Qiangang, Li, Anmin, Pan, Liwen

“…This paper mainly investigated the effect of the Mn/Ag ratio on the microstructure and room temperature and high-temperature (350 °C) tensile mechanical…”
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