Search Results - "Chen, Zizhen"
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Gain of function of ASXL1 truncating protein in the pathogenesis of myeloid malignancies
Published in Blood (18-01-2018)“…Additional Sex Combs-Like 1 (ASXL1) is mutated at a high frequency in all forms of myeloid malignancies associated with poor prognosis. We generated a Vav1…”
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Therapeutic potential of GSK-J4, a histone demethylase KDM6B/JMJD3 inhibitor, for acute myeloid leukemia
Published in Journal of cancer research and clinical oncology (01-06-2018)“…Purpose Acute myeloid leukemia (AML) is a heterogeneous disease with poor outcomes. Despite increased evidence shows that dysregulation of histone modification…”
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3
Recognition and analysis system of steel stamping character based on machine vision
Published in Automatika (02-07-2024)“…During the packaging process, it is essential to detect the steel stamping characters inside the box to identify any missing or repeated characters. Currently,…”
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The Effects of Spatial Resolution and Resampling on the Classification Accuracy of Wetland Vegetation Species and Ground Objects: A Study Based on High Spatial Resolution UAV Images
Published in Drones (Basel) (01-01-2023)“…When employing remote sensing images, it is challenging to classify vegetation species and ground objects due to the abundance of wetland vegetation species…”
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Evaluation of driving effects of carbon storage change in the source of the Yellow River: A perspective with CMIP6 future development scenarios
Published in Ecological informatics (01-11-2024)“…Understanding how future climate scenarios impact land use/cover (LUC) and carbon storage (CS) is crucial for achieving carbon neutrality. However, research…”
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Explainable machine learning-based fractional vegetation cover inversion and performance optimization – A case study of an alpine grassland on the Qinghai-Tibet Plateau
Published in Ecological informatics (01-09-2024)“…Fractional Vegetation Cover (FVC) serves as a crucial indicator in ecological sustainability and climate change monitoring. While machine learning is the…”
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The Spatiotemporal Variation in Biodiversity and Its Response to Different Future Development Scenarios: A Case Study of Guilin as an Internationally Renowned Tourist Destination in China
Published in Applied sciences (01-03-2024)“…The preservation of biodiversity is crucial for maintaining ecological balance and promoting the harmonious development of mankind and nature. To formulate a…”
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Synthesis, odor characteristics and thermal behaviors of pyrrole esters
Published in Journal of Saudi Chemical Society (01-03-2023)“…A novel approach for transesterification of methyl pyrrole-carboxylate with alcohols is reported. The transformation is performed with t-BuOK and a series of…”
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Associations between nine dietary minerals intake and all-cause mortality in individuals with atherosclerotic cardiovascular disease
Published in Frontiers in nutrition (Lausanne) (14-10-2024)“…Varied intake of dietary minerals critically affects cardiovascular health. This study examines the associations of nine dietary minerals intake with all-cause…”
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The miR-106b-25 cluster mediates drug resistance in myeloid leukaemias by inactivating multiple apoptotic genes
Published in International journal of hematology (01-02-2023)“…Drug resistance is a major obstacle to the successful treatment of cancer. The role of the miR-106b-25 cluster in drug resistance of haematologic malignancies…”
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TET2 Loss Dysregulates the Behavior of Bone Marrow Mesenchymal Stromal Cells and Accelerates Tet2−/−-Driven Myeloid Malignancy Progression
Published in Stem cell reports (09-01-2018)“…TET2 is a methylcytosine dioxygenase that regulates cytosine hydroxymethylation. Although there are extensive data implicating a pivotal role of TET2 in…”
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12
Loss of ASXL1 in the bone marrow niche dysregulates hematopoietic stem and progenitor cell fates
Published in Cell discovery (23-01-2018)“…Somatic or de novo mutations of Additional sex combs-like 1 ( ASXL1 ) frequently occur in patients with myeloid malignancies or Bohring-Opitz syndrome,…”
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Frontiers in the emerging development of blockchain and Bitcoin: visual research based on big data analysis
Published in E3S web of conferences (01-01-2021)“…In the era of the rapid development of information technology, the innovation of Fintech continues to send emerging research hotspots to the financial market…”
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Journal Article Conference Proceeding -
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The Research Fronts of Financial Market Risk Prevention in the Background of Big Data Analysis: Scientific Measurement Analysis from Multidisciplinary Literature
Published in E3S Web of Conferences (01-01-2020)“…Risks are ubiquitous in financial markets, and the occurrence of financial crises has never stopped. In order to provide research fronts for financial market…”
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Journal Article Conference Proceeding -
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Bipartite Grid Partitioning of a Random Geometric Graph
Published in 2017 13th International Conference on Distributed Computing in Sensor Systems (DCOSS) (01-06-2017)“…We investigate the problem of efficient computation of a partition of a Random Geometric Graph (RGG) into a limited number of densely packed bipartite grid…”
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Conference Proceeding -
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A novel 4‐mRNA signature predicts the overall survival in acute myeloid leukemia
Published in American journal of hematology (01-11-2021)“…Acute myeloid leukemia (AML) is an aggressive cancer of myeloid cells with high levels of heterogeneity and great variability in prognostic behaviors…”
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MiR-106b-25 Promotes Chemoresistance in Acute Myeloid Leukemia Via Abolishing Multiple Apoptotic Pathways
Published in Blood (23-11-2021)“…Introduction: Chemoresistance and disease relapse remain the main obstacles responsible for treatment failure in leukemia. MicroRNAs (miRNAs) play essential…”
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3145 – MIR-106B-25 PROMOTES CHEMORESISTANCE IN ACUTE MYELOID LEUKEMIA VIA ABOLISHING MULTIPLE APOPTOTIC PATHWAYS
Published in Experimental hematology (01-08-2021)“…Chemoresistance and disease relapse remain the main obstacles responsible for treatment failure in cancer. We have previously reported that microRNA (miRNA)…”
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Reducing hyperactivated BAP1 attenuates mutant ASXL1-driven myeloid malignancies in human haematopoietic cells
Published in Cancer letters (28-10-2021)“…Additional sex combs-like 1 (ASXL1) is frequently mutated in a variety of myeloid malignancies, resulting in expression of a C-terminal-truncated ASXL1 protein…”
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Tradeoffs among multi-source remote sensing images, spatial resolution, and accuracy for the classification of wetland plant species and surface objects based on the MRS_DeepLabV3+ model
Published in Ecological informatics (01-07-2024)“…Classification of wetland plant species (PlatSpe) and surface objects (SurfObj) in remote sensing images faces significant challenges due to the high diversity…”
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