Search Results - "Chen, Zhenghe"
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Identification of a Twelve-Gene Signature and Establishment of a Prognostic Nomogram Predicting Overall Survival for Medulloblastoma
Published in Frontiers in genetics (03-09-2020)“…Medulloblastoma is the common pediatric malignant tumor with poor prognosis in cerebellum. However, MB is always with clinical heterogeneity. To provide…”
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Prognostic value of the modified systemic inflammation score in non-small-cell lung cancer with brain metastasis
Published in Cancer cell international (14-10-2022)“…Abstract Background Brain metastases (BM) from non-small-cell lung cancer (NSCLC) is the most common brain malignancy. Systemic inflammation biomarkers have…”
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Prognostic Value of the Systemic Immune-Inflammation Index and Prognostic Nutritional Index in Patients With Medulloblastoma Undergoing Surgical Resection
Published in Frontiers in nutrition (Lausanne) (17-12-2021)“…The progression and metastasis of cancers are associated with systematic immune inflammation and nutritional dysfunction. The systemic immune-inflammation…”
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Real-world management and survival outcomes of patients with newly diagnosed gliomas from a single institution in China: A retrospective cohort study
Published in Glioma (Mumbai, India) (01-01-2019)“…Background and Aim: Guidelines recommend adjuvant treatment for patients with high-grade gliomas and low-grade gliomas with high risk of progression. In…”
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Phase 2 clinical trial of VAL-083 as first-line treatment in newly-diagnosed MGMT-unmethylated glioblastoma multiforme (GBM): Halfway report
Published in Glioma (Mumbai, India) (01-01-2019)“…Background and Aim: Approximately 60% of glioblastoma multiforme (GBM) patients possess an unmethylated O-6-methylguanine-DNA methyltransferase (MGMT) gene,…”
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FLGS-03. Fluorescein sodium-guided biopsy or resection in patients with contrast enhancing brainstem lesion in MRI
Published in Neuro-oncology (Charlottesville, Va.) (12-11-2021)“…Abstract BACKGROUND It is challenging to resect or just biopsy the lesions in the brainstem, due to the essential function of the surfaces and limited space…”
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Complications following titanium cranioplasty compared with nontitanium implants cranioplasty: A systematic review and meta-analysis
Published in Journal of clinical neuroscience (01-02-2021)“…•We compared complications rate between titanium cranioplasty with nontitanium materials cranioplasty.•Our results confirmed the advantages of titanium…”
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PATH-06. ASSESSMENT OF CIRCULATING TUMOR DNA IN CEREBROSPINAL FLUID BY WHOLE EXOME SEQUENCING TO DETECT GENOMIC ALTERATIONS OF GLIOBLASTOMA
Published in Neuro-oncology (Charlottesville, Va.) (09-11-2020)“…Abstract Cerebrospinal fluid (CSF) has been demonstrated as a better source of circulating tumor DNA (ctDNA) than plasma for brain tumors. However, it is…”
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Speed control system design of automatic parking based on fuzzy-PID control
Published in 2017 IEEE International Conference on Information and Automation (ICIA) (01-07-2017)“…A general structure of motor-brake pedal is put forward to solve the problem of automatic parking system for intelligent driving on traditional fuel vehicles…”
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CTNI-05. A PROSPECTIVE STUDY OF TUMOR-TREATING FIELDS COMBINED WITH SYSTEMIC THERAPY IN RECURRENT GLIOBLASTOMA
Published in Neuro-oncology (Charlottesville, Va.) (11-11-2024)“…Abstract BACKGROUND Tumor-treating Fields (TTFields) monotherapy was approved for recurrent glioblastoma. However, TTFields combined with systemic therapy has…”
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Multi-parametric Z-spectral MRI may have a good performance for glioma stratification in clinical patients
Published in European radiology (2022)“…Objectives To comprehensively and noninvasively risk-stratify glioma grade, isocitrate dehydrogenase (IDH) genotype, and 1p/19q codeletion status using…”
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PSMA PET/MR is a New Imaging Option for Identifying Glioma Recurrence and Predicting Prognosis
Published in Recent patents on anti-cancer drug discovery (01-01-2024)“…Glioma is characterized by a high recurrence rate, while the results of the traditional imaging methods (including magnetic resonance imaging, MRI) to…”
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The Association Between Socioeconomic Factors at Diagnosis and Survival in Medulloblastoma: A Propensity Score-Matched Analysis and Population-Based Study
Published in Journal of racial and ethnic health disparities (01-08-2024)“…Background Medulloblastoma (MB) is the most common malignant brain tumor of childhood. The associations between socioeconomic statuses (SES) and survival…”
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Effective natural inhibitors targeting poly ADP-ribose polymerase by computational study
Published in Aging (Albany, NY.) (23-01-2021)“…This study was designed to screen ideal lead compounds and drug candidates with an inhibitory effect on PARP from the drug library (ZINC database). Two…”
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SURG-06. FOLLOWING INTRAOPERATIVE TUMOR-FREE PRINCIPLES IS AN EFFECTIVE APPROACH TO IMPROVE SURVIVAL OF PATIENTS WITH GLIOBLASTOMA
Published in Neuro-oncology (Charlottesville, Va.) (11-11-2019)“…Abstract The intraoperative tumor-free principles refer to the operation techniques that must be carried out to prevent the exfoliation and planting of tumor…”
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Computational study on novel natural inhibitors targeting BCL2
Published in Medical oncology (Northwood, London, England) (01-08-2021)“…Ideal lead compounds and candidate drugs with inhibitory effect on BCL2 were screened from ZINC database, which laid a foundation for drug development and…”
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Unique genomic features and prognostic value of COSMIC mutational signature 4 in lung adenocarcinoma and lung squamous cell carcinoma
Published in Annals of translational medicine (01-09-2020)“…Analysis of mutational signatures is becoming routine in cancer genomics, with implications for pathogenesis, classification, and prognosis. Among the…”
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An Unusual Combination of Mirror-Image Dextrocardia with Familial Medulloblastoma: Is There a Histogenetic Relationship?
Published in World neurosurgery (01-11-2017)“…The occurrence of medulloblastoma in the absence of hereditary syndromes is rare. Dextrocardia with situs inversus is also called mirror-image dextrocardia. A…”
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Adjuvant Temozolomide Chemotherapy With or Without Interferon Alfa Among Patients With Newly Diagnosed High-grade Gliomas: A Randomized Clinical Trial
Published in JAMA network open (03-01-2023)“…High-grade gliomas (HGGs) constitute the most common and aggressive primary brain tumor, with 5-year survival rates of 30.9% for grade 3 gliomas and 6.6% for…”
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