Search Results - "Chen, Zhe S."
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Mapping Cortical Integration of Sensory and Affective Pain Pathways
Published in Current biology (04-05-2020)“…Pain is an integrated sensory and affective experience. Cortical mechanisms of sensory and affective integration, however, remain poorly defined. Here, we…”
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From Antimicrobial to Anticancer Peptides: The Transformation of Peptides
Published in Recent patents on anti-cancer drug discovery (01-01-2019)“…Antimicrobial peptides play an important role in the innate immune system. Possessing broad-spectrum antibacterial activity, antimicrobial peptides can quickly…”
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Enzyme and Transporter Kinetics for CPT-11 (Irinotecan) and SN-38: An Insight on Tumor Tissue Compartment Pharmacokinetics Using PBPK
Published in Recent patents on anti-cancer drug discovery (01-01-2019)“…Computational tools are becoming more and more powerful and comprehensive as compared to past decades in facilitating pharmaceutical, pharmacological and…”
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Stimulus-Driven and Spontaneous Dynamics in Excitatory-Inhibitory Recurrent Neural Networks for Sequence Representation
Published in Neural computation (16-09-2021)“…Recurrent neural networks (RNNs) have been widely used to model sequential neural dynamics ("neural sequences") of cortical circuits in cognitive and motor…”
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Neural dynamics in the limbic system during male social behaviors
Published in Neuron (Cambridge, Mass.) (18-10-2023)“…Sexual and aggressive behaviors are vital for species survival and individual reproductive success. Although many limbic regions have been found relevant to…”
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Efficient Position Decoding Methods Based on Fluorescence Calcium Imaging in the Mouse Hippocampus
Published in Neural computation (01-06-2020)“…Large-scale fluorescence calcium imaging methods have become widely adopted for studies of long-term hippocampal and cortical neuronal dynamics. Pyramidal…”
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Deep Learning Based on Standard H&E Images of Primary Melanoma Tumors Identifies Patients at Risk for Visceral Recurrence and Death
Published in Clinical cancer research (01-03-2020)“…Biomarkers for disease-specific survival (DSS) in early-stage melanoma are needed to select patients for adjuvant immunotherapy and accelerate clinical trial…”
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Uncovering spatial representations from spatiotemporal patterns of rodent hippocampal field potentials
Published in Cell reports methods (22-11-2021)“…Spatiotemporal patterns of large-scale spiking and field potentials of the rodent hippocampus encode spatial representations during maze runs, immobility, and…”
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On the Role of Theory and Modeling in Neuroscience
Published in The Journal of neuroscience (15-02-2023)“…In recent years, the field of neuroscience has gone through rapid experimental advances and a significant increase in the use of quantitative and computational…”
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A prototype closed-loop brain–machine interface for the study and treatment of pain
Published in Nature biomedical engineering (01-04-2023)“…Chronic pain is characterized by discrete pain episodes of unpredictable frequency and duration. This hinders the study of pain mechanisms and contributes to…”
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Predictive coding models for pain perception
Published in Journal of computational neuroscience (01-05-2021)“…Pain is a complex, multidimensional experience that involves dynamic interactions between sensory-discriminative and affective-emotional processes. Pain…”
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Sleep spindles as a diagnostic and therapeutic target for chronic pain
Published in Molecular pain (01-01-2020)“…Pain is known to disrupt sleep patterns, and disturbances in sleep can further worsen pain symptoms. Sleep spindles occur during slow wave sleep and have…”
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A case of duodenal ulcer as prominent manifestation of IgG4-related disease
Published in Beijing da xue xue bao. Journal of Peking University. Yi xue ban (18-12-2023)“…A case of IgG4-related disease presented with a duodenal ulcer to improve the understan-ding of IgG4-related diseases was reported. A 70-year-old male…”
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Study on Correctness of Memory Security Dynamic Detection Algorithm Based on Theorem Proving
Published in Ji suan ji ke xue (01-01-2021)“…With the development and improvement of software runtime verification technology,many C-oriented runtime memory security verification tools have appeared.Most…”
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Memory Security Vulnerability Detection Combining Fuzzy Testing and Dynamic Analysis
Published in Ji suan ji ke xue (01-01-2024)“…C language is widely used in the development of system software and embedded software due to its high speed and precise control of memory through pointers, and…”
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SCADE Model Checking Based on Program Transformation
Published in Ji suan ji ke xue (01-12-2021)“…SCADE synchronization language is a common programming language for embedded system.It is often used to realize real-time embedded automatic control system in…”
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Systematic review and Meta-analysis of efficacy and safety of Shumian Capsules in treatment of insomnia
Published in Zhongguo zhongyao zazhi (01-01-2024)“…This study aims to assess the safety and efficacy of Shumian Capsules in the treatment of insomnia. Randomized controlled trial(RCT) about Shumian Capsules for…”
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Analysis of epigenetic modification gene mutations among patients with acute myeloid leukemia
Published in Zhonghua yi xue yi chuan xue za zhi (10-04-2023)“…To investigate the carrier rate and clinical characteristics of epigenetic modification gene mutations (EMMs) among patients with acute myeloid leukemia (AML)…”
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