Search Results - "Chen, Zhaowei"
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Local and Targeted Delivery of Immune Checkpoint Blockade Therapeutics
Published in Accounts of chemical research (17-11-2020)“…Conspectus Immune checkpoint blockade (ICB) therapy elicits antitumor response by inhibiting immune suppressor components, including programmed cell death…”
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Biomimetic nanoflowers by self-assembly of nanozymes to induce intracellular oxidative damage against hypoxic tumors
Published in Nature communications (20-08-2018)“…Reactive oxygen species (ROS)-induced apoptosis is a promising treatment strategy for malignant neoplasms. However, current systems are highly dependent on…”
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Copper(II)-Graphitic Carbon Nitride Triggered Synergy: Improved ROS Generation and Reduced Glutathione Levels for Enhanced Photodynamic Therapy
Published in Angewandte Chemie International Edition (12-09-2016)“…Graphitic carbon nitride (g‐C3N4) has been used as photosensitizer to generate reactive oxygen species (ROS) for photodynamic therapy (PDT). However, its…”
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Metal-Organic-Framework-Based Vaccine Platforms for Enhanced Systemic Immune and Memory Response
Published in Advanced functional materials (01-09-2016)“…Nanoparticulate delivery platforms have shown promising advantages for vaccines in many aspects. However, their application was limited so far by lengthy…”
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Activation of biologically relevant levels of reactive oxygen species by Au/g-C3N4 hybrid nanozyme for bacteria killing and wound disinfection
Published in Biomaterials (01-01-2017)“…As common reactive oxygen species, H2O2 is widely used for bacterial inactivation and wound disinfection. However, the concentrations used are always higher…”
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Transition of acute kidney injury to chronic kidney disease: role of metabolic reprogramming
Published in Metabolism, clinical and experimental (01-06-2022)“…Acute kidney injury (AKI) is a global public health concern associated with high morbidity and mortality. Although advances in medical management have improved…”
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Mesoporous silica-encapsulated gold nanoparticles as artificial enzymes for self-activated cascade catalysis
Published in Biomaterials (01-04-2013)“…Abstract A significant challenge in chemistry is to create synthetic structures that mimic the complexity and function of natural systems. Here, a…”
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Light Controlled Reversible Inversion of Nanophosphor-Stabilized Pickering Emulsions for Biphasic Enantioselective Biocatalysis
Published in Journal of the American Chemical Society (21-05-2014)“…In this work, by utilizing photochromic spiropyrans conjugated upconversion nanophosphors, we have successfully prepared NIR/visible light tuned interfacially…”
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Exceptional point engineered glass slide for microscopic thermal mapping
Published in Nature communications (02-05-2018)“…Thermal sensing with fine spatial resolution is important to the study of many scientific areas. While modern microscopy systems allow optical detection at…”
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10
Visible-light-driven enhanced antibacterial and biofilm elimination activity of graphitic carbon nitride by embedded Ag nanoparticles
Published in Nano research (01-05-2015)“…Semiconductor nanomaterials with photocatalytic activity have potential for many applications. An effective way of promoting photocatalytic activity is…”
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Fibrotic microtissue array to predict anti-fibrosis drug efficacy
Published in Nature communications (25-05-2018)“…Fibrosis is a severe health problem characterized by progressive stiffening of tissues which causes organ malfunction and failure. A major bottleneck in…”
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Synthetic beta cells for fusion-mediated dynamic insulin secretion
Published in Nature chemical biology (01-01-2018)“…Synthetic beta cells were fabricated through 'vesicles-in-vesicle' liposomal superstructures equipped with glucose-sensing and membrane-fusion machinery, thus…”
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Near-infrared absorbing mesoporous carbon nanoparticle as an intelligent drug carrier for dual-triggered synergistic cancer therapy
Published in Carbon (New York) (01-02-2015)“…Herein a novel multifunctional nanoplatform based on surface engineered mesoporous carbon nanoparticle (MCN) is developed for effective dual-triggered…”
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14
Roles of Mitochondrial DNA Damage in Kidney Diseases: A New Biomarker
Published in International journal of molecular sciences (02-12-2022)“…The kidney is a mitochondria-rich organ, and kidney diseases are recognized as mitochondria-related pathologies. Intact mitochondrial DNA (mtDNA) maintains…”
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Bioresponsive Hyaluronic Acid-Capped Mesoporous Silica Nanoparticles for Targeted Drug Delivery
Published in Chemistry : a European journal (28-01-2013)“…In this paper, we present a facile strategy to synthesize hyaluronic acid (HA) conjugated mesoporous silica nanoparticles (MSP) for targeted enzyme responsive…”
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Design of Surface-Active Artificial Enzyme Particles to Stabilize Pickering Emulsions for High-Performance Biphasic Biocatalysis
Published in Advanced materials (Weinheim) (24-02-2016)“…Surface‐active artificial enzymes (SAEs) are designed and constructed by a general and novel strategy. These SAEs can simultaneously stabilize Pickering…”
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Gaseous Plastron on Natural and Biomimetic Surfaces for Resisting Marine Biofouling
Published in Molecules (Basel, Switzerland) (29-04-2021)“…In recent years, various biomimetic materials capable of forming gaseous plastron on their surfaces have been fabricated and widely used in various disciplines…”
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An Alternative Solution of Train-Track Dynamic Interaction
Published in Shock and vibration (2019)“…Train-track interaction (TTI) is a classic research topic in railway engineering, which consists of three main parts, namely, train model, track model, and…”
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DEM Modeling of Interaction Between the Propagating Fracture and Multiple Pre-existing Cemented Discontinuities in Shale
Published in Rock mechanics and rock engineering (01-06-2019)“…It is known that pre-existing discontinuities can act as planes of weakness that divert the propagating fractures in rocks, but previous studies have mostly…”
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Effects of fracture filling ratio and confining stress on the equivalent effective stress coefficient of rocks containing a single fracture
Published in International journal of rock mechanics and mining sciences (Oxford, England : 1997) (01-12-2022)“…Because fractures are ubiquitous in rock masses, the states of stress and fracture filling significantly impact the coupled hydromechanical behaviors of…”
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