Search Results - "Chen, Zhaosu"
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SET8 prevents excessive DNA methylation by methylation-mediated degradation of UHRF1 and DNMT1
Published in Nucleic acids research (26-09-2019)“…Faithful inheritance of DNA methylation across cell division requires DNMT1 and its accessory factor UHRF1. However, how this axis is regulated to ensure DNA…”
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Nuclear UHRF1 is a gate-keeper of cellular AMPK activity and function
Published in Cell research (01-01-2022)“…The AMP-activated protein kinase (AMPK) is a central regulator of energy homeostasis. Although much has been learned on how low energy status and glucose…”
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MYC promotes global transcription in part by controlling P-TEFb complex formation via DNA-binding independent inhibition of CDK9 SUMOylation
Published in Science China. Life sciences (01-09-2023)“…MYC is an oncogenic transcription factor with a novel role in enhancing global transcription when overexpressed. However, how MYC promotes global transcription…”
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USP7 negatively controls global DNA methylation by attenuating ubiquitinated histone-dependent DNMT1 recruitment
Published in Cell discovery (24-08-2020)“…Previous studies have implicated an essential role for UHRF1-mediated histone H3 ubiquitination in recruiting DNMT1 to replication sites for DNA maintenance…”
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SUMOylation is enriched in the nuclear matrix and required for chromosome segregation
Published in The Journal of biological chemistry (01-01-2024)“…As an important posttranslational modification, SUMOylation plays critical roles in almost all biological processes. Although it has been well-documented that…”
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Linking nuclear matrix–localized PIAS1 to chromatin SUMOylation via direct binding of histones H3 and H2A.Z
Published in The Journal of biological chemistry (01-10-2021)“…As a conserved posttranslational modification, SUMOylation has been shown to play important roles in chromatin-related biological processes including…”
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Control of SOX2 protein stability and tumorigenic activity by E3 ligase CHIP in esophageal cancer cells
Published in Oncogene (21-07-2023)“…SOX2 is highly expressed and controls tumor initiation and cancer stem cell function in various squamous cell carcinomas including esophageal squamous cancer…”
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Effect of Polyacrylic Acid Additives on Anodic Oxidation Film on Magnesium Alloy
Published in Cai liao bao hu (01-09-2022)“…In order to further improve the corrosion resistance of the anodic oxidation film on magnesium alloy, polyacrylic acid (PAA) was added into the base…”
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Effect of Vacuum Annealing on the Microstructure and Properties of Ti Coating on Magnesium Alloys
Published in Cai liao bao hu (01-11-2022)“…In order to improve the corrosion resistance of magnesium alloys, Ti coatings were prepared on the surface of AZ91D magnesium alloy by means of magnetron…”
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