Search Results - "Chen, Zhao‐Xia"

Interfering with Lactate‐Fueled Respiration for Enhanced Photodynamic Tumor Therapy by a Porphyrinic MOF Nanoplatform by Chen, Zhao‐Xia, Liu, Miao‐Deng, Zhang, Ming‐Kang, Wang, Shi‐Bo, Xu, Lu, Li, Chu‐Xin, Gao, Fan, Xie, Bo‐Ru, Zhong, Zhen‐Lin, Zhang, Xian‐Zheng

“…Lactate is a prominent energy substrate for oxidative tumor cells. Interfering with the lactate‐fueled respiration of oxidative tumor cells would be a…”
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Flavonoidal alkaloids from the flowers of Chromolaena odorata (L.) R.M.King & H.Rob by Yang, Jian-Ni, Yi, Ji-Ling, Zou, Jing-Hua, Chen, Zhao-Xia, Chen, Guang-Ying, Hui, Yang, Sun, Zhen-Fan, Chen, Wen-Hao

“…A pair of epimers of flavonoid alkaloids, with a pyrrolidone moiety, 2S,5′′R-eupodoratin A (1), 2S,5′′S-eupodoratin A (2), together with two known analogues,…”
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The Histone Methyltransferase SETDB1 and the DNA Methyltransferase DNMT3A Interact Directly and Localize to Promoters Silenced in Cancer Cells by Li, Hongwei, Rauch, Tibor, Chen, Zhao-Xia, Szabó, Piroska E., Riggs, Arthur D., Pfeifer, Gerd P.

“…DNA CpG methylation can cooperate with histone H3 lysine 9 (H3-K9) methylation in heterochromatin formation and gene silencing. Trimethylation of H3-K9 by the…”
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Physical and functional interactions between the human DNMT3L protein and members of the de novo methyltransferase family by Chen, Zhao-Xia, Mann, Jeffrey R., Hsieh, Chih-Lin, Riggs, Arthur D., Chédin, Frédéric

“…The de novo methyltransferase‐like protein, DNMT3L, is required for methylation of imprinted genes in germ cells. Although enzymatically inactive, human DNMT3L…”
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Global sensitivity analysis of the AquaCrop model for winter wheat under different water treatments based on the extended Fourier amplitude sensitivity test by XING, Hui-min, XU, Xin-gang, LI, Zhen-hai, CHEN, Yi-jin, FENG, Hai-kuan, YANG, Gui-jun, CHEN, Zhao-xia

“…Sensitivity analysis （SA） is an effective tool for studying crop models; it is an important link in model localization and plays an important role in crop…”
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Identification of Oct4-activating compounds that enhance reprogramming efficiency by Li, Wendong, Tian, E, Chen, Zhao-Xia, Sun, GuoQiang, Ye, Peng, Yang, Su, Lu, Dave, Xie, Jun, Ho, Thach-Vu, Tsark, Walter M., Wang, Charles, Horne, David A., Riggs, Arthur D., Yip, M. L. Richard, Shi, Yanhong

“…One of the hurdles for practical application of induced pluripotent stem cells (iPSC) is the low efficiency and slow process of reprogramming. Octamer-binding…”
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The antisense strand of small interfering RNAs directs histone methylation and transcriptional gene silencing in human cells by Weinberg, Marc S, Villeneuve, Louisa M, Ehsani, Ali, Amarzguioui, Mohammed, Aagaard, Lars, Chen, Zhao-Xia, Riggs, Arthur D, Rossi, John J, Morris, Kevin V

“…To determine mechanistically how siRNAs mediate transcriptional gene silencing (TGS) in human cells, we have measured histone methylation at targeted…”
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CpG island clusters and pro-epigenetic selection for CpGs in protein-coding exons of HOX and other transcription factors by Branciamore, Sergio, Chen, Zhao-Xia, Riggs, Arthur D., Rodin, Sergei N.

“…CpG dinucleotides contribute to epigenetic mechanisms by being the only site for DNA methylation in mammalian somatic cells. They are also mutation hotspots…”
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DNA Methylation and Demethylation in Mammals by Chen, Zhao-xia, Riggs, Arthur D.

“…Cell type-specific DNA methylation patterns are established during mammalian development and maintained in adult somatic cells. Understanding how these…”
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Remodeling extracellular matrix based on functional covalent organic framework to enhance tumor photodynamic therapy by Wang, Shi-Bo, Chen, Zhao-Xia, Gao, Fan, Zhang, Cheng, Zou, Mei-Zhen, Ye, Jing-Jie, Zeng, Xuan, Zhang, Xian-Zheng

“…Photodynamic therapy (PDT) is a promising treatment modality for tumor suppression. However, the hypoxic state of most solid tumors might largely hinder the…”
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A Versatile Carbon Monoxide Nanogenerator for Enhanced Tumor Therapy and Anti-Inflammation by Wang, Shi-Bo, Zhang, Cheng, Chen, Zhao-Xia, Ye, Jing-Jie, Peng, Si-Yuan, Rong, Lei, Liu, Chuan-Jun, Zhang, Xian-Zheng

“…Carbon monoxide (CO) is regarded as a potential therapeutic agent with multiple beneficial functions for biomedical applications. In this study, a versatile CO…”
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Regulation of prostate cancer by hormone-responsive G protein-coupled receptors by Wang, Wei, Chen, Zhao-Xia, Guo, Dong-Yu, Tao, Ya-Xiong

“…Regulation of prostate cancer by androgen and androgen receptor (AR), and blockade of AR signaling by AR antagonists and steroidogenic enzyme inhibitors have…”
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Combination gut microbiota modulation and chemotherapy for orthotopic colorectal cancer therapy by Chen, Zhao-Xia, Li, Jiang-Lan, Pan, Pei, Bao, Peng, Zeng, Xuan, Zhang, Xian-Zheng

“…Gut microbiota is closely related to the tumorigenesis and progression of colorectal cancer (CRC), especially Fusobacterium nucleatum (Fn) could promote…”
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Mutations in DNA methyltransferase DNMT3B in ICF syndrome affect its regulation by DNMT3L by Xie, Zheng-Hua, Huang, Yan-Nv, Chen, Zhao-Xia, Riggs, Arthur D., Ding, Jian-Ping, Gowher, Humaira, Jeltsch, Albert, Sasaki, Hiroyuki, Hata, Kenichiro, Xu, Guo-Liang

“…Deficiency in DNA methyltransferase DNMT3B causes a recessive human disorder characterized by immunodeficiency, centromeric instability and facial anomalies…”
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Self-Reinforced Cancer Targeting (SRCT) Depending on Reciprocally Enhancing Feedback between Targeting and Therapy by Ye, Jing-Jie, Yu, Wuyang, Xie, Bo-Ru, Li, Ke, Liu, Miao-Deng, Dong, Xue, Chen, Zhao-Xia, Feng, Jun, Zhang, Xian-Zheng

“…Conventional cancer targeting methodology needs to be reformed to overcome the intrinsic barriers responsible for poor targeting efficiency. This study…”
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Studies on Secondary Metabolites and Biological Activities of Fungus Aspergillus sp. PQJ-1 from Sphagneticola trilobata by Chen, Zhao-Xia, Chen, Wen-Hao, Li, Shu-Hui, Chen, Fei-Fei, Li, Mu-Yang, Li, Wen-Xing, Hui, Yang

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High damping capacities of Mg-Cu based alloys by 万迪庆 何柏林 熊光耀 陈朝霞 王锦程 杨根仓

“…The dynamic mechanical analyzer（DMA）was applied to investigate the damping properties of Mg-Cu based alloys.The results show that the as-cast hypoeutectic…”
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A Tungsten Nitride‐Based O 2 Self‐Sufficient Nanoplatform for Enhanced Photodynamic Therapy against Hypoxic Tumors by Wang, Shi‐Bo, Zhang, Cheng, Liu, Xin‐Hua, Chen, Zhao‐Xia, Peng, Si‐Yuan, Zhong, Zhen‐Lin, Zhang, Xian‐Zheng

“…Abstract The hypoxic microenvironment of tumors is a natural barrier to photodynamic therapy (PDT) and closely related to the tumor metastasis. Here, chlorine…”
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A Tungsten Nitride‐Based O2 Self‐Sufficient Nanoplatform for Enhanced Photodynamic Therapy against Hypoxic Tumors by Wang, Shi‐Bo, Zhang, Cheng, Liu, Xin‐Hua, Chen, Zhao‐Xia, Peng, Si‐Yuan, Zhong, Zhen‐Lin, Zhang, Xian‐Zheng

“…The hypoxic microenvironment of tumors is a natural barrier to photodynamic therapy (PDT) and closely related to the tumor metastasis. Here, chlorine e6 (Ce6)…”
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Maintenance and regulation of DNA methylation patterns in mammals by Chen, Zhao-xia, Riggs, Arthur D

“…Proper establishment and faithful maintenance of epigenetic information is crucial for the correct development of complex organisms. For mammals, it is now…”
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