Search Results - "Chen, Zengyi"

Increased atrial and brain natriuretic peptides in adults with cyanotic congenital heart disease : Enhanced understanding of the relationship between hypoxia and natriuretic peptide secretion by HOPKINS, William E, ZENGYI CHEN, FUKAGAWA, Naomi K, HALL, Christian, KNOT, Harm J, LEWINTER, Martin M

“…Brain natriuretic peptide (BNP) levels are used in the evaluation of patients with heart disease, yet there is little understanding of the effect of hypoxia on…”
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Zinc-induced cardiomyocyte relaxation in a rat model of hyperglycemia is independent of myosin isoform by Yi, Ting, Cheema, Yaser, Tremble, Sarah M, Bell, Stephen P, Chen, Zengyi, Subramanian, Meenakumari, LeWinter, Martin M, VanBuren, Peter, Palmer, Bradley M

“…It has been reported previously that diabetic cardiomyopathy can be inhibited or reverted with chronic zinc supplementation. In the current study, we…”
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Cardiac Myosin Binding Protein-C Is Essential for Thick-Filament Stability and Flexural Rigidity by Nyland, Lori R., Palmer, Bradley M., Chen, Zengyi, Maughan, David W., Seidman, Christine E., Seidman, J.G., Kreplak, Laurent, Vigoreaux, Jim O.

“…Using atomic force microscopy, we examined the contribution of cardiac myosin binding protein-C (cMyBP-C) to thick-filament length and flexural rigidity…”
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Effects of cardiac myosin isoform variation on myofilament function and crossbridge kinetics in transgenic rabbits by Suzuki, Takeki, Palmer, Bradley M, James, Jeanne, Wang, Yuan, Chen, Zengyi, VanBuren, Peter, Maughan, David W, Robbins, Jeffrey, LeWinter, Martin M

“…The left ventricles of both rabbits and humans express predominantly beta-myosin heavy chain (MHC). Transgenic (TG) rabbits expressing 40% alpha-MHC are…”
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N-Acetylcysteine–Enhanced Contrast Provides Cardiorenal Protection by Meyer, Markus, MD, FACC, LeWinter, Martin M., MD, FACC, Bell, Stephen P., BA, Chen, Zengyi, MD, Selby, Donald E., PhD, Singla, Dinender K., PhD, Dauerman, Harold L., MD, FACC

“…N-Acetylcysteine–Enhanced Contrast Provides Cardiorenal Protection Markus Meyer, Martin M. LeWinter, Stephen P. Bell, Zengyi Chen, Donald E. Selby, Dinender K…”
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Mechanoenergetic alterations during the transition from cardiac hypertrophy to failure in Dahl salt-sensitive rats by KAMEYAMA, T, ZENGYI CHEN, BELL, S. P, VANBUREN, P, MAUGHAN, D, LEWINTER, M. M

“…The time course and mechanisms of altered mechanoenergetics and depressed cross-bridge cycling in hypertrophied and failing myocardium are uncertain. We…”
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Mechanoenergetic studies in isolated mouse hearts by Kameyama, T, Chen, Z, Bell, S P, Fabian, J, LeWinter, M M

“…We tested the feasibility of an isolated, balloon-in-ventricle, isovolumically contracting, crystalloid-perfused mouse heart preparation (n = 10) for studies…”
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Effects of EMD 57033 on contraction and relaxation in isolated rabbit hearts by HGASHIYAMA, A, WATKINS, M. W, CHEN, Z, LEWINTER, M. M

“…Ca2+ sensitizers are reported to enhance contractility with modest effects on energy utilization. In the present study we assessed the effects of the…”
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Competitive Regulation of Calcium and Zinc Ions in Cardiomyocyte Contraction-Relaxation Function by Yi, Ting, Chen, Zengyi, Lachapelle, Rich, Palmer, Bradley M.

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Differential metal content and gene expression in rat left ventricular hypertrophy due to hypertension and hyperactivity by Subramanian, Meenakumari, Hunt, Adam L., Petrucci, Giuseppe A., Chen, Zengyi, Hendley, Edith D., Palmer, Bradley M.

“…The spontaneously hypertensive rat (SHR) has been studied extensively as a model of left ventricular hypertrophy (LVH) and associated cardiac dysfunction due…”
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The sinus node inhibitor UL-FS 49 lacks significant inotropic effect by Chen, Z Y, Slinker, B K

“…UL-FS 49 is a sinus node inhibitor that has been reported to reduce heart rate and may be useful in improving myocardial oxygen supply vs. demand. However,…”
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Extracellular Zinc Enhances Cardiomyocyte Relaxation Function in Diabetic Rats by Yi, Ting, Chen, Zengyi, Van Buren, Peter C., Palmer, Bradley M.

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Intracellular distributions of essential elements in cardiomyocytes by Palmer, Bradley M., Vogt, Stefan, Chen, Zengyi, Lachapelle, Richard R., LeWinter, Martin M.

“…We describe the intracellular distributions of nine essential elements (P, S, Cl, K, Ca, Mn, Fe, Cu, and Zn) found in cardiomyocytes imaged using synchrotron…”
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High dose intracoronary N-acetylcysteine in a porcine model of ST-elevation myocardial infarction by Meyer, Markus, Bell, Stephen P., Chen, Zengyi, Nyotowidjojo, Iwan, Lachapelle, Richard R., Christian, Timothy F., Gibson, Pamela C., Keating, Friederike F., Dauerman, Harold L., LeWinter, Martin M.

“…We sought to evaluate the safety and efficacy of N -acetylcysteine (NAC) on ischemia and reperfusion in a pig model focusing on cardio-renal protection. High…”
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Cardiac Mysin Binding Protein-C Is Essential for Thick-Filament Stability and Flexural Rigidity by Nyland, Lori R, Palmer, Bradley M, Chen, Zengyi, Maughan, David W, Seidman, Christine E, Seidman, JG, Kreplak, Laurent, Vigoreaux, Jim O

“…Using atomic force microscopy, we examined the contribution of cardiac myosin binding protein-C (cMyBP-C) to thick-filament length and flexural rigidity…”
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Acute Effects of Biventricular Versus Right Ventricular Pacing on Left Ventricular Function and Twist Assessed by Magnetic Resonance Imaging in a Canine Post Myocardial Infarction Model of Cardiomyopathy by Masood, Yasmin, VanBuren, Peter, Lustgarten, Daniel, Christian, Timothy, Calame, James, Chen, Zengyi, Bell, Stephen, LeWinter, Martin M

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Cardiomyocyte function associated with hyperactivity and/or hypertension in genetic models of LV hypertrophy by Palmer, Bradley M, Chen, Zengyi, Lachapelle, Richard R, Hendley, Edith D, LeWinter, Martin M

“…We examined cardiomyocyte intracellular calcium ([Ca2+]i) dynamics and sarcomere shortening dynamics in genetic rat models of left ventricular (LV) hypertrophy…”
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Endothelin receptor blockade has an oxygen-saving effect in Dahl salt-sensitive rats with heart failure by Noguchi, Teruo, Chen, Zengyi, Bell, Stephen P, Nyland, Lori, LeWinter, Martin M

“…The effects of endothelin (ET) receptor blockade on energy utilization in heart failure (HF) are unknown. We administered ET type A (ETA), ET type B (ETB), and…”
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Activation of PKC decreases myocardial O2 consumption and increases contractile efficiency in rats by Noguchi, T, Chen, Z, Bell, S P, Nyland, L, LeWinter, M M

“…The effect of protein kinase C (PKC) activation on cardiac mechanoenergetics is not fully understood. To address this issue, we determined the effects of the…”
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Altered Expression of Troponin T Isoforms in Mild Left Ventricular Hypertrophy in the Rabbit by Chen, Zengyi, Higashiyama, Akihiro, Yaku, Hitoshi, Bell, Stephen, Fabian, Judit, Watkins, Matthew W., Schneider, David J., Maughan, David W., LeWinter, Martin M.

“…Alterations in troponin T (TnT) isoforms have been reported in severe human and experimental heart failure (HF), and may play a role in the depressed…”
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