Search Results - "Chen, Yuanhong"
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Purification and characterization of exopolysaccharide produced by Weissella cibaria YB-1 from pickle Chinese cabbage
Published in International journal of biological macromolecules (01-12-2018)“…An exopolysaccharide (EPS) was produced by Weissella cibaria YB-1 isolated from pickle Chinese cabbage. The EPS was purified and characterized. The…”
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The Hippo Pathway Effector YAP Regulates Motility, Invasion, and Castration-Resistant Growth of Prostate Cancer Cells
Published in Molecular and cellular biology (01-04-2015)“…Yes-associated protein (YAP) is an effector of the Hippo tumor suppressor pathway. The functional significance of YAP in prostate cancer has remained elusive…”
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Association between Serum Creatinine and Osteoporosis in Early Postmenopausal Women: A Cross-Sectional Study
Published in Clinical and experimental obstetrics & gynecology (01-02-2024)“…Background: Low bone mineral density (BMD) is the hallmark of osteoporosis, postmenopausal women are more likely to have microarchitectural deterioration and…”
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Substrate sustained release-based high efficacy biosynthesis of GABA by Lactobacillus brevis NCL912
Published in Microbial cell factories (19-05-2018)“…Gamma-aminobutyric acid (GABA) plays a significant role in the food and drug industries. Our previous study established an efficient fed-batch fermentation…”
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5
A Review on Multiple I-III-VI Quantum Dots: Preparation and Enhanced Luminescence Properties
Published in Materials (17-07-2023)“…I-III-VI type QDs have unique optoelectronic properties such as low toxicity, tunable bandgaps, large Stokes shifts and a long photoluminescence lifetime, and…”
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Cyclin-dependent kinase 1-mediated AMPK phosphorylation regulates chromosome alignment and mitotic progression
Published in Journal of cell science (15-10-2019)“…AMP-activated protein kinase (AMPK), a heterotrimeric serine/threonine kinase and cellular metabolic sensor, has been found to regulate cell cycle checkpoints…”
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CDK1 Phosphorylation of YAP Promotes Mitotic Defects and Cell Motility and Is Essential for Neoplastic Transformation
Published in Cancer research (Chicago, Ill.) (15-11-2013)“…The Yes-associated protein, YAP, is a downstream effector of the Hippo pathway of cell-cycle control that plays important roles in tumorigenesis…”
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CDK1-mediated mitotic phosphorylation of PBK is involved in cytokinesis and inhibits its oncogenic activity
Published in Cellular signalling (01-11-2017)“…PDZ-binding kinase (PBK) plays a major role in proliferation and in safeguarding mitotic fidelity in cancer cells. Frequently upregulated in many cancers, PBK…”
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Activation of ALOX12 by a multi-organelle-orienting photosensitizer drives ACSL4-independent cell ferroptosis
Published in Cell death & disease (14-12-2022)“…Ferroptosis is a recently-defined tumor suppression mechanism, but the sensitivity of many tumorigenic cells to ferroptosis is limited by their deficient…”
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USP26 as a hepatitis B virus-induced deubiquitinase primes hepatocellular carcinogenesis by epigenetic remodeling
Published in Nature communications (09-09-2024)“…Despite recent advances in systemic therapy for hepatocellular carcinoma (HCC), the prognosis of hepatitis B virus (HBV)-induced HCC patients remains poor. By…”
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Chronic zebrafish PFOS exposure alters sex ratio and maternal related effects in F1 offspring
Published in Environmental toxicology and chemistry (01-09-2011)“…Perfluorooctanesulfonic acid (PFOS) is an organic contaminant ubiquitous in the environment, wildlife, and humans. Few studies have assessed its chronic…”
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Protein kinase RNA-activated controls mitotic progression and determines paclitaxel chemosensitivity through B-cell lymphoma 2 in ovarian cancer
Published in Oncogene (16-12-2021)“…Anti-tubulin agents, such as paclitaxel, have been used extensively for treatment of several types of cancer, including ovarian, lung, breast, and pancreatic…”
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Cyclin-dependent kinase 1 (CDK1)-mediated mitotic phosphorylation of the transcriptional co-repressor Vgll4 inhibits its tumor-suppressing activity
Published in The Journal of biological chemistry (08-09-2017)“…The Hippo pathway is an evolutionarily conserved signaling pathway that plays important roles in stem cell biology, tissue homeostasis, and cancer development…”
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Oncoprotein YAP Regulates the Spindle Checkpoint Activation in a Mitotic Phosphorylation-dependent Manner through Up-regulation of BubR1
Published in The Journal of biological chemistry (06-03-2015)“…The transcriptional co-activator YAP (Yes-associated protein) functions as an oncogene; however, it is largely unclear how YAP exerts its oncogenic role. In…”
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Cyclin-dependent kinase 1-mediated phosphorylation of SET at serine 7 is essential for its oncogenic activity
Published in Cell death & disease (16-05-2019)“…SE translocation (SET), an inhibitor of protein phosphatase 2A (PP2A), plays important roles in mitosis and possesses oncogenic activity in several types of…”
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ZHX2 deficiency enriches hybrid MET cells through regulating E-cadherin expression
Published in Cell death & disease (17-07-2023)“…Growing evidence indicates that the epithelial to mesenchymal (E/M) hybrid state plays a key role in tumorigenesis. Importantly, a hybrid mesenchymal to…”
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Active YAP promotes pancreatic cancer cell motility, invasion and tumorigenesis in a mitotic phosphorylation-dependent manner through LPAR3
Published in Oncotarget (03-11-2015)“…The transcriptional co-activator Yes-associated protein, YAP, is a main effector in the Hippo tumor suppressor pathway. We recently defined a mechanism for…”
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Comparison of AI-integrated pathways with human-AI interaction in population mammographic screening for breast cancer
Published in Nature communications (30-08-2024)“…Artificial intelligence (AI) readers of mammograms compare favourably to individual radiologists in detecting breast cancer. However, AI readers cannot perform…”
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Celecoxib targets breast cancer stem cells by inhibiting the synthesis of prostaglandin E2 and down-regulating the Wnt pathway activity
Published in Oncotarget (29-12-2017)“…Pharmacological targeting of breast cancer stem cells (CSCs) is highly promising for the treatment of breast cancer, as the small population of CSCs is…”
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Multi‐trait genomic selection improves the prediction accuracy of end‐use quality traits in hard winter wheat
Published in The plant genome (01-12-2023)“…Improvement of end‐use quality remains one of the most important goals in hard winter wheat (HWW) breeding. Nevertheless, the evaluation of end‐use quality…”
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