Search Results - "Chen, Yequn"
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Difference in Leukocyte Composition between Women before and after Menopausal Age, and Distinct Sexual Dimorphism
Published in PloS one (22-09-2016)“…There are sex differences in many inflammatory and immune diseases, and the differences tend to diminish after menopause. The underlying reasons are unclear,…”
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The signature of SARS-CoV-2-related genes predicts the immune therapeutic response and prognosis in breast cancer
Published in BMC medical genomics (31-10-2024)“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an exceptionally contagious single-stranded RNA virus with a strong positive contagion. The…”
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3
LncRNA CDKN2B-AS1 stabilized by IGF2BP3 drives the malignancy of renal clear cell carcinoma through epigenetically activating NUF2 transcription
Published in Cell death & disease (19-02-2021)“…Because of the lack of sensitivity to radiotherapy and chemotherapy, therapeutic options for renal clear cell carcinoma (KIRC) are scarce. Long noncoding RNAs…”
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Association of triglyceride-glucose index with the risk of incident aortic dissection and aneurysm: a large-scale prospective cohort study in UK Biobank
Published in Cardiovascular diabetology (02-08-2024)“…Triglyceride-glucose (TyG) index is an emerging surrogate indicator of insulin resistance, which has been demonstrated as a risk factor for various…”
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5
Association of uterine fibroids with increased blood pressure: a cross-sectional study and meta-analysis
Published in Hypertension research (01-04-2022)“…Uterine fibroids (UFs) are the most common benign gynecological tumor and greatly affect reproductive health in women of reproductive age. Some studies have…”
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Prevalence and management of depressive symptoms in coronary heart disease patients and relationship with cardiovascular prognosis: a prospective cohort study
Published in BMC psychiatry (30-09-2024)“…Depressive symptoms are comorbid with coronary heart disease (CHD). There is a controversial debate about whether screening and intervention for depressive…”
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Visceral fat and its dynamic change are associated with renal damage: Evidence from two cohorts
Published in Clinical and experimental hypertension (1993) (31-12-2023)“…BACKGROUND AND AIMSTo evaluate the association of Chinese visceral adiposity index (CVAI) and its dynamic trends with risk of renal damage, and to compare its…”
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Homocysteine activates vascular smooth muscle cells by DNA demethylation of platelet-derived growth factor in endothelial cells
Published in Journal of molecular and cellular cardiology (01-10-2012)“…Abstract Hyperhomocysteinemia (HHcy), as an independent risk factor of atherosclerosis, facilitates endothelial dysfunction and activation of vascular smooth…”
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Impacts of molecular drivers in aortic dissection
Published in Clinical and translational discovery (01-08-2024)“…Background Aortic dissection (AD) is a lethal cardiovascular emergency involving high mortality and disability. However, its specific pathogenesis remains to…”
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10
Maternal depression and preeclampsia: Effects on the maternal and offspring's mental and physical health
Published in Heart and mind (Mumbai, India) (01-01-2022)“…Prenatal depression and preeclampsia (PE) are well-known risk factors of maternal and fetal mortality and morbidity. In recent years, there are emerging…”
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Effects on tricuspid regurgitation by different techniques for passing permanent pacemaker leads through the tricuspid valve: a randomized, open-label, superiority clinical trial study protocol
Published in Current controlled trials in cardiovascular medicine (15-11-2024)“…Background In recent years, lead-induced tricuspid regurgitation (LITR) has attracted increasing attention. At present, there are two commonly used…”
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12
Homocysteine Upregulates Soluble Epoxide Hydrolase in Vascular Endothelium In Vitro and In Vivo
Published in Circulation research (16-03-2012)“…RATIONALE:Hyperhomocysteinemia is a risk factor of atherogenesis. Soluble epoxide hydrolase (sEH) is a major enzyme that hydrolyzes epoxyeicosatrienoic acids…”
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Genetic and epigenetic associations of ANRIL with coronary artery disease and risk factors
Published in BMC medical genomics (06-10-2021)“…Both DNA genotype and methylation of antisense non-coding RNA in the INK4 locus (ANRIL) have been robustly associated with coronary artery disease (CAD), but…”
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Effect of probiotic supplementation on in-hospital mortality in patients with acute myocardial infarction: a study protocol for an open-label, randomized, controlled, superiority clinical trial
Published in Current controlled trials in cardiovascular medicine (24-06-2023)“…Recent studies have demonstrated a correlation between intestinal flora and the severity of myocardial infarction as well as post-myocardial infarction repair…”
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Coronary-Heart-Disease-Associated Genetic Variant at the COL4A1/COL4A2 Locus Affects COL4A1/COL4A2 Expression, Vascular Cell Survival, Atherosclerotic Plaque Stability and Risk of Myocardial Infarction
Published in PLoS genetics (01-07-2016)“…Genome-wide association studies have revealed an association between coronary heart disease (CHD) and genetic variation on chromosome 13q34, with the lead…”
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Susceptibility Modules and Genes in Hypertrophic Cardiomyopathy by WGCNA and ceRNA Network Analysis
Published in Frontiers in cell and developmental biology (01-02-2022)“…We attempted to identify a regulatory competing endogenous RNA (ceRNA) network and a hub gene of Hypertrophic Cardiomyopathy (HCM). Microarray datasets of HCM…”
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Correlation analysis of gamma-glutamyl transferase to lymphocyte ratio and patients with acute aortic syndrome in China: a propensity score-matched analysis
Published in Frontiers in cardiovascular medicine (01-07-2024)“…Acute aortic syndrome (AAS) is a life-threatening condition in which there is a fracture in the integrity of the aortic wall. gamma-glutamyl transferase to…”
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Effect of sacubitril/valsartan on sinus rhythm maintenance after catheter ablation in patients with persistent atrial fibrillation without reduced ejection fraction heart failure: a study protocol for a multi-center, open-label, randomized, controlled, superiority clinical trial
Published in Frontiers in cardiovascular medicine (2024)“…A high recurrence rate of atrial fibrillation was monitored after catheter ablation for persistent atrial fibrillation. Sacubitril/valsartan can improve…”
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Predicting 1-, 3-, 5-, and 8-year all-cause mortality in a community-dwelling older adult cohort: relevance for predictive, preventive, and personalized medicine
Published in The EPMA journal (01-12-2023)“…Background Population aging is a global public health issue involving increased prevalence of age-related diseases, and concomitant burden on medical resources…”
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Efficiency of atorvastatin on in-hospital mortality of patients with acute aortic dissection (AAD): study protocol for a randomized, open-label, superiority clinical trial
Published in Current controlled trials in cardiovascular medicine (14-04-2021)“…Dyslipidemia and local inflammation at sites of lipid deposition on blood vessel walls have been demonstrated to be risk factors for patients with acute aortic…”
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