Search Results - "Chen, Yangshan"

Deep learning-based six-type classifier for lung cancer and mimics from histopathological whole slide images: a retrospective study by Yang, Huan, Chen, Lili, Cheng, Zhiqiang, Yang, Minglei, Wang, Jianbo, Lin, Chenghao, Wang, Yuefeng, Huang, Leilei, Chen, Yangshan, Peng, Sui, Ke, Zunfu, Li, Weizhong

“…Targeted therapy and immunotherapy put forward higher demands for accurate lung cancer classification, as well as benign versus malignant disease…”
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Combined evaluation of the expression status of CD155 and TIGIT plays an important role in the prognosis of LUAD (lung adenocarcinoma) by Sun, Yu, Luo, Jiping, Chen, Yangshan, Cui, Ji, Lei, Yiyan, Cui, Yongmei, Jiang, Neng, Jiang, Wenting, Chen, Lili, Chen, Yanyang, Kuang, Yukun, Tang, Kejing, Ke, Zunfu

“…•Lung cancer remains the most lethal tumor that urges better prognosis prediction.•CD155 and TIGIT are promising onco-immunologic molecules in lung…”
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The role of E3 ubiquitin ligases in bone homeostasis and related diseases by Dong, Yuechao, Chen, Yangshan, Ma, Guixing, Cao, Huiling

“…The ubiquitin–proteasome system (UPS) dedicates to degrade intracellular proteins to modulate demic homeostasis and functions of organisms. These enzymatic…”
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CTHRC1 induces non-small cell lung cancer (NSCLC) invasion through upregulating MMP-7/MMP-9 by He, Weiling, Zhang, Hui, Wang, Yuefeng, Zhou, Yanbin, Luo, Yifeng, Cui, Yongmei, Jiang, Neng, Jiang, Wenting, Wang, Han, Xu, Di, Li, Shuhua, Wang, Zhuo, Chen, Yangshan, Sun, Yu, Zhang, Yang, Tseng, Hsian-Rong, Zou, Xuenong, Wang, Liantang, Ke, Zunfu

“…The strong invasive and metastatic nature of non-small cell lung cancer (NSCLC) leads to poor prognosis. Collagen triple helix repeat containing 1 (CTHRC1) is…”
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Talin-1 inhibits Smurf1-mediated Stat3 degradation to modulate β-cell proliferation and mass in mice by Hou, Xiaoting, Chen, Yangshan, Zhou, Bo, Tang, Wanze, Ding, Zhen, Chen, Litong, Wu, Yun, Yang, Hongyu, Du, Changzheng, Yang, Dazhi, Ma, Guixing, Cao, Huiling

“…Insufficient pancreatic β-cell mass and reduced insulin expression are key events in the pathogenesis of diabetes mellitus (DM). Here we demonstrate the high…”
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High CTHRC1 expression may be closely associated with angiogenesis and indicates poor prognosis in lung adenocarcinoma patients by Chen, Yangshan, Sun, Yu, Cui, Yongmei, Lei, Yiyan, Jiang, Neng, Jiang, Wenting, Wang, Han, Chen, Lili, Luo, Jiping, Chen, Yanyang, Tang, Kejing, Zhou, Chengzhi, Ke, Zunfu

“…This study aimed to investigate the prognostic value of the potential biomarker collagen triple helix repeat containing 1 (CTHRC1) in lung adenocarcinoma…”
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Three-dimensional nanostructured substrates enable dynamic detection of ALK-rearrangement in circulating tumor cells from treatment-naive patients with stage III/IV lung adenocarcinoma by He, Weiling, Xu, Di, Wang, Zhuo, Wu, Hui, Xiang, Xianhong, Tang, Bing, Jiang, Wenting, Cui, Yongmei, Wang, Han, Jiang, Neng, Sun, Yu, Chen, Yangshan, Li, Shuhua, Hou, Minzhi, Zhang, Yang, Wang, Liantang, Ke, Zun-Fu

“…Circulating tumor cells (CTC) shows great prospect to realize precision medicine in cancer patients. We developed the NanoVelcro Chip integrating three…”
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Overcoming T790M mutant small cell lung cancer with the third‐generation EGFR‐TKI osimertinib by Tang, Kejing, Jiang, Neng, Kuang, Yukun, He, Qiong, Li, Shuhua, Luo, Jiping, Jiang, Wenting, Chen, Yangshan, Sun, Yu, Chen, Lili, Chen, Yanyang, Zhu, Junfeng, Cui, Yongmei, Wan, Han, Ke, Zunfu

“…A large number of EGFR mutant non‐small cell lung cancer patients primordially benefit from first‐line treatment with first‐generation EGFR‐tyrosine kinase…”
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Kindlin-2 controls angiogenesis through modulating Notch1 signaling by Dong, Yuechao, Ma, Guixing, Hou, Xiaoting, Han, Yingying, Ding, Zhen, Tang, Wanze, Chen, Litong, Chen, Yangshan, Zhou, Bo, Rao, Feng, Lv, Kaosheng, Du, Changzheng, Cao, Huiling

“…Kindlin-2 is critical for development and homeostasis of key organs, including skeleton, liver, islet, etc., yet its role in modulating angiogenesis is…”
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A whole-slide image (WSI)-based immunohistochemical feature prediction system improves the subtyping of lung cancer by Chen, Yanyang, Yang, Huan, Cheng, Zhiqiang, Chen, Lili, Peng, Sui, Wang, Jianbo, Yang, Minglei, Lin, Chenghao, Chen, Yu, Wang, Yuefeng, Huang, Leilei, Chen, Yangshan, Li, Weizhong, Ke, Zunfu

“…Clinically, accurate pathological diagnosis is often challenged by insufficient tissue amounts and the unaffordability of additional immunohistochemical or…”
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Development and Validation of a Novel Signature to Predict Overall Survival in "Driver Gene-negative" Lung Adenocarcinoma (LUAD): Results of a Multicenter Study by Cui, Yongmei, Fang, Wenfeng, Li, Chaofeng, Tang, Kejing, Zhang, Jian, Lei, Yiyan, He, Weiling, Peng, Sui, Kuang, Ming, Zhang, Hui, Chen, Lili, Xu, Di, Tang, Cuilan, Zhang, Wenhui, Zhu, Yuxin, Jiang, Wenting, Jiang, Neng, Sun, Yu, Chen, Yangshan, Wang, Han, Lai, Yingrong, Li, Shuhua, He, Qiong, Zhou, Jianwen, Zhang, Yang, Lin, Millicent, Chen, Honglei, Zhou, Chenzhi, Wang, Chunlin, Wang, Jianhong, Zou, Xuenong, Wang, Liantang, Ke, Zunfu

“…Examining the role of developmental signaling pathways in "driver gene-negative" lung adenocarcinoma (patients with lung adenocarcinoma negative for , and were…”
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Clinical significance of circulating tumor cells in predicting disease progression and chemotherapy resistance in patients with gestational choriocarcinoma by He, Weiling, Hou, Minzhi, Zhang, Hui, Zeng, Chao, He, Shanyang, Chen, Xinlin, Xu, Manman, Sun, Cong, Jiang, Wenting, Wang, Han, Shen, Hongwei, Zhang, Yang, Liu, Jing, Sun, Shijun, Jiang, Neng, Cui, Yongmei, Sun, Yu, Chen, Yangshan, Cao, Jessica, Wang, Chunlin, Li, Mengzhen, Zhang, Yi, Wang, Liantang, Wang, Jianhong, Lin, Millicent, Ke, Zunfu

“…Gestational choriocarcinoma (GC) is a highly aggressive tumor. In our study, we systematically investigated EpCAM/CD147 expression characteristics in patients…”
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Targeting miR-29 mitigates skeletal senescence and bolsters therapeutic potential of mesenchymal stromal cells by Ding, Zhen, Ma, Guixing, Zhou, Bo, Cheng, Siyuan, Tang, Wanze, Han, Yingying, Chen, Litong, Pang, Wei, Chen, Yangshan, Yang, Dazhi, Cao, Huiling

“…Mesenchymal stromal cell (MSC) senescence is a key factor in skeletal aging, affecting the potential of MSC applications. Identifying targets to prevent MSC…”
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NanoVelcro-captured CTC number concomitant with enhanced serum levels of MMP7 and MMP9 enables accurate prediction of metastasis and poor prognosis in patients with lung adenocarcinoma by Sun, Yu, Chen, Yangshan, Li, Shuhua, Lei, Yiyan, Xu, Di, Jiang, Neng, Zhang, Yang, Cao, Jessica, Ke, Zunfu

“…Lung adenocarcinoma (LADC) is among the most malignant cancers that frequently develops micrometastases even in early stages of the disease. Circulating tumor…”
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Polymer nanofiber-based microchips for EGFR mutation analysis of circulating tumor cells in lung adenocarcinoma by Jiang, Wenting, Wang, Han, Cui, Yongmei, Lei, Yiyan, Wang, Yuefeng, Xu, Di, Jiang, Neng, Chen, Yangshan, Sun, Yu, Zhang, Yang, Cao, Jessica, Ke, Zunfu

“…Circulating tumor cells (CTCs) detection, an approach considered to be "liquid biopsy", is a potential alternative method in clinical use for early diagnosis…”
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HIF-1ɑ-regulated miR-1275 maintains stem cell-like phenotypes and promotes the progression of LUAD by simultaneously activating Wnt/β-catenin and Notch signaling by Jiang, Neng, Zou, Chang, Zhu, Ying, Luo, Yifeng, Chen, Lili, Lei, Yiyan, Tang, Kejing, Sun, Yu, Zhang, Wenhui, Li, Shuhua, He, Qiong, Zhou, Jianwen, Chen, Yangshan, Luo, Jiping, Jiang, Wenting, Ke, Zunfu

“…: Cancer stem cells (CSCs) are considered to be essential for tumorigenesis, recurrence, and metastasis and therefore serve as a biomarker for tumor…”
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Auxiliary diagnostic value of p16 amplification combined with the detection of heterozygous and homozygous loss for urothelial carcinoma by Mao, Xiaopeng, Li, Baimou, Liang, Ying, Li, Shuhua, Zhou, Jianwen, He, Qiong, Jiang, Neng, Chen, Yangshan, Sun, Yu, Cui, Yongmei, Jiang, Wenting, Wang, Han, Wang, Liantang, Ke, Zunfu

“…The present study aimed to investigate the significance of detecting cyclin dependent kinase inhibitor 2A (p16) gene aberrations in the diagnosis of urothelial…”
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Overcoming T790M mutant small cell lung cancer with the third-generation EGFR-TKI osimertinib by Tang, Kejing, Jiang, Neng, Kuang, Yukun, He, Qiong, Li, Shuhua, Luo, Jiping, Jiang, Wenting, Chen, Yangshan, Sun, Yu, Chen, Lili, Chen, Yanyang, Zhu, Junfeng, Cui, Yongmei, Wan, Han, Ke, Zunfu

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