Search Results - "Chen, Yangchao"
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Detection of COVID-19: A review of the current literature and future perspectives
Published in Biosensors & bioelectronics (15-10-2020)“…The rapid spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to the coronavirus disease 2019 (COVID-19) worldwide pandemic. This…”
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LINC01133 can induce acquired ferroptosis resistance by enhancing the FSP1 mRNA stability through forming the LINC01133-FUS-FSP1 complex
Published in Cell death & disease (25-11-2023)“…Due to a lack of research on the critical non-coding RNAs in regulating ferroptosis, our study aimed to uncover the crucial ones involved in the process. We…”
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The Impact of TRPV1 on Cancer Pathogenesis and Therapy: A Systematic Review
Published in International journal of biological sciences (01-01-2021)“…The transient receptor potential cation channel subfamily V member 1 (TRPV1) is a transmembrane protein that can be activated by various physical and chemical…”
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Activation of PTEN by inhibition of TRPV4 suppresses colon cancer development
Published in Cell death & disease (12-06-2019)“…Transient receptor potential vanilloid type 4 (TRPV4) is a Ca 2+ -permeable cation channel that is known to be an osmosensor and thermosensor. Currently,…”
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Targeting EZH2 for cancer therapy: progress and perspective
Published in Current protein & peptide science (01-01-2015)“…Enhancer of Zeste Homolog 2 (EZH2) is the core component of the polycomb repressive complex 2 (PRC2), possessing the enzymatic activity in generating…”
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Noncoding RNA regulates the expression of Krm1 and Dkk2 to synergistically affect aortic valve lesions
Published in Experimental & molecular medicine (01-07-2024)“…Calcific aortic valve disease (CAVD) is becoming an increasingly important global medical problem, but effective pharmacological treatments are lacking…”
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Genetic variants rs2910164, rs4636297 and rs895819 may contribute to the onset of acute myocardial infarction in Pakistani population
Published in PloS one (02-01-2024)“…The most serious type of coronary artery disease (CAD), acute myocardial infarction (AMI), is a major global cause of death. The development of AMI is…”
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CircRTN4 promotes pancreatic cancer progression through a novel CircRNA-miRNA-lncRNA pathway and stabilizing epithelial-mesenchymal transition protein
Published in Molecular cancer (04-01-2022)“…Circular RNAs (circRNAs) play important roles in many biological processes. However, the detailed mechanism underlying the critical roles of circRNAs in cancer…”
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Transient Receptor Potential Cation Channel Subfamily V Member 1 Expression Promotes Chemoresistance in Non-Small-Cell Lung Cancer
Published in Frontiers in oncology (25-03-2022)“…Approximately 85% of lung cancer cases are non-small-cell lung cancer (NSCLC). Chemoresistance is a leading cause of chemotherapy failure in NSCLC treatment…”
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Hepatitis B virus X protein promotes hepatocellular carcinoma transformation through interleukin-6 activation of microRNA-21 expression
Published in European journal of cancer (1990) (01-10-2014)“…Abstract Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide, and chronic hepatitis B virus (HBV) infection is the major risk factor of…”
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Ectopic HOTTIP expression induces noncanonical transactivation pathways to promote growth and invasiveness in pancreatic ductal adenocarcinoma
Published in Cancer letters (01-05-2020)“…HOXA transcript at the distal tip (HOTTIP), a long noncoding RNA, is upregulated in pancreatic ductal adenocarcinoma (PDAC), but the HOTTIP–mediated oncogenic…”
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Revisit complexation between DNA and polyethylenimine — Effect of uncomplexed chains free in the solution mixture on gene transfection
Published in Journal of controlled release (10-10-2011)“…Our revisit of the complexation between anionic DNA and cationic polyethylenimine (PEI) in both water and phosphate buffered saline (PBS) by using a…”
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Exploration of a Novel Electric-Fuse Device with a Simple Structure of Ni Metal on a SiO2 Dielectric for Electrostatic Discharge Protection under a Human Body Model
Published in Micromachines (Basel) (19-09-2024)“…On-chip electrostatic discharge (ESD) protection poses a challenge in the chip fabrication process. In this study, a novel electric fuse (E-fuse) device…”
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EZH2-Mediated Concordant Repression of Wnt Antagonists Promotes β-Catenin-Dependent Hepatocarcinogenesis
Published in Cancer research (Chicago, Ill.) (01-06-2011)“…Enhancer of zeste homolog 2 (EZH2) is the catalytic subunit of the Polycomb-repressive complex 2 (PRC2) that represses gene transcription through histone H3…”
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A novel tRNA-derived fragment AS-tDR-007333 promotes the malignancy of NSCLC via the HSPB1/MED29 and ELK4/MED29 axes
Published in Journal of hematology and oncology (07-05-2022)“…Transfer RNA-derived fragments (tRFs) are a new class of small non-coding RNAs. Recent studies suggest that tRFs participate in some pathological processes…”
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Revisit the complexation of PEI and DNA — How to make low cytotoxic and highly efficient PEI gene transfection non-viral vectors with a controllable chain length and structure?
Published in Journal of controlled release (16-11-2009)“…The commercially available branched polyethyleneimine (PEI) with a molar mass of 25 kD (PEI-25K) is an effective in vitro vector to transfer genes, but its…”
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Bone Morphogenic Protein-4 Impairs Endothelial Function Through Oxidative Stress–Dependent Cyclooxygenase-2 Upregulation: Implications on Hypertension
Published in Circulation research (15-10-2010)“…RATIONALE:Bone morphogenic protein (BMP)4 can stimulate superoxide production and exert proinflammatory effects on the endothelium. The underlying mechanisms…”
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microRNA-146b inhibits glioma cell migration and invasion by targeting MMPs
Published in Brain research (07-05-2009)“…Abstract MicroRNAs (miRNAs) are a class of endogenous, small non-protein coding single-stranded RNA molecules, which are crucial post-transcriptional…”
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Small and Long Non-Coding RNAs: Novel Targets in Perspective Cancer Therapy
Published in Current genomics (01-10-2015)“…Non-coding RNA refers to a large group of endogenous RNA molecules that have no protein coding capacity, while having specialized cellular and molecular…”
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Effect of Berberine on promoting the excretion of cholesterol in high-fat diet-induced hyperlipidemic hamsters
Published in Journal of translational medicine (27-08-2015)“…Berberine (BBR), as a new medicine for hyperlipidemia, can reduce the blood lipids in patients. Mechanistic studies have shown that BBR activates the…”
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