Search Results - "Chen, Yamei"

A body map of somatic mutagenesis in morphologically normal human tissues by Li, Ruoyan, Di, Lin, Li, Jie, Fan, Wenyi, Liu, Yachen, Guo, Wenjia, Liu, Weiling, Liu, Lu, Li, Qiong, Chen, Liping, Chen, Yamei, Miao, Chuanwang, Liu, Hongjin, Wang, Yuqian, Ma, Yuling, Xu, Deshu, Lin, Dongxin, Huang, Yanyi, Wang, Jianbin, Bai, Fan, Wu, Chen

“…Somatic mutations that accumulate in normal tissues are associated with ageing and disease 1 , 2 . Here we performed a comprehensive genomic analysis of 1,737…”
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Ibrutinib and novel BTK inhibitors in clinical development by Akinleye, Akintunde, Chen, Yamei, Mukhi, Nikhil, Song, Yongping, Liu, Delong

“…Small molecule inhibitors targeting dysregulated pathways (RAS/RAF/MEK, PI3K/AKT/mTOR, JAK/STAT) have significantly improved clinical outcomes in cancer…”
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Dissecting esophageal squamous-cell carcinoma ecosystem by single-cell transcriptomic analysis by Zhang, Xiannian, Peng, Linna, Luo, Yingying, Zhang, Shaosen, Pu, Yang, Chen, Yamei, Guo, Wenjia, Yao, Jiacheng, Shao, Mingming, Fan, Wenyi, Cui, Qionghua, Xi, Yiyi, Sun, Yanxia, Niu, Xiangjie, Zhao, Xuan, Chen, Liping, Wang, Yuqian, Liu, Yachen, Yang, Xinyu, Wang, Chengcheng, Zhong, Ce, Tan, Wen, Wang, Jianbin, Wu, Chen, Lin, Dongxin

“…Esophageal squamous-cell carcinoma (ESCC), one of the most prevalent and lethal malignant disease, has a complex but unknown tumor ecosystem. Here, we…”
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Increased plant growth may offset soil carbon loss caused by warming in an alpine Sibiraea angustata shrub ecosystem on the eastern Qinghai-Tibet Plateau by Ma, Zhiliang, Chen, Yamei, Xu, Wenjuan, Liu, Mei

“…[Display omitted] •C storage of plants and soils were studied in an alpine shrubland under warming.•C storage of alpine shrub stem did not affect by…”
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Hub genes and associated drugs for multiple myeloma with 1q21+: identified by bioinformatic analysis by Xu, Zhiqiang, Yu, Jieni, Chen, Yamei

“…While 1q21+ was common genetic alteration and found to have adverse effect on prognosis, the underlying genes remain unclear. Identification of related genes…”
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Expanding PROTACtable genome universe of E3 ligases by Liu, Yuan, Yang, Jingwen, Wang, Tianlu, Luo, Mei, Chen, Yamei, Chen, Chengxuan, Ronai, Ze’ev, Zhou, Yubin, Ruppin, Eytan, Han, Leng

“…Proteolysis-targeting chimera (PROTAC) and other targeted protein degradation (TPD) molecules that induce degradation by the ubiquitin-proteasome system (UPS)…”
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Single-cell transcriptomic analysis in a mouse model deciphers cell transition states in the multistep development of esophageal cancer by Yao, Jiacheng, Cui, Qionghua, Fan, Wenyi, Ma, Yuling, Chen, Yamei, Liu, Tianyuan, Zhang, Xiannian, Xi, Yiyi, Wang, Chengcheng, Peng, Linna, Luo, Yingying, Lin, Ai, Guo, Wenjia, Lin, Lin, Lin, Yuan, Tan, Wen, Lin, Dongxin, Wu, Chen, Wang, Jianbin

“…Esophageal squamous cell carcinoma (ESCC) is prevalent in some geographical regions of the world. ESCC development presents a multistep pathogenic process from…”
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Rapid Estrogen Receptor-Mediated Mechanisms Determine the Sexually Dimorphic Sensitivity of Ventricular Myocytes to 17β-Estradiol and the Environmental Endocrine Disruptor Bisphenol A by Belcher, Scott M, Chen, Yamei, Yan, Sujuan, Wang, Hong-Sheng

“…Previously we showed that 17β-estradiol (E2) and/or the xenoestrogen bisphenol A (BPA) alter ventricular myocyte Ca2+ handing, resulting in increased cardiac…”
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Bisphenol A and 17β-estradiol promote arrhythmia in the female heart via alteration of calcium handling by Yan, Sujuan, Chen, Yamei, Dong, Min, Song, Weizhong, Belcher, Scott M, Wang, Hong-Sheng

“…There is wide-spread human exposure to bisphenol A (BPA), a ubiquitous estrogenic endocrine disruptor that has been implicated as having potentially harmful…”
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A Study of the Influence of the Type of Land Use on the Enzymatic Activity of Soils in Southwestern China by Zhiliang Ma, Wenjuan Xu, Yamei Chen, Mei Liu, Jiahao Wen

“…Although soil enzyme activity can act as an effective indicator of soil nutrient status, there is some uncertainty about its accuracy within soil depth across…”
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Molecular Mechanisms Underlying the Rapid Arrhythmogenic Action of Bisphenol A in Female Rat Hearts by Gao, Xiaoqian, Liang, Qian, Chen, Yamei, Wang, Hong-Sheng

“…Previously we showed that bisphenol A (BPA), an environmental estrogenic endocrine disruptor, rapidly altered Ca2+ handling and promoted arrhythmias in female…”
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Household Energy Consumption Patterns and Carbon Emissions for the Megacities—Evidence from Guangzhou, China by Jiang, Lu, Ding, Bowenpeng, Shi, Xiaonan, Li, Chunhua, Chen, Yamei

“…Over the last 20 years, energy consumption in the residential sector in China has grown rapidly, and the growth is faster than that of any other energy form…”
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A multi‐omics perspective of CAR T cell therapy by Yang, Jingwen, Chen, Yamei, Han, Leng

“…As omics technologies, including genomics, epigenomics, transcriptomics, T cell receptor‐repertorie profiling, proteomics, metabolomics and microbiomics, have…”
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The Impact of Nitrogen Application on Leaf and Root Functional Traits of Davidia involucrata Saplings by Mei Liu, Jiahao Wen, Wenjuan Xu, Yamei Chen, Zhiliang Ma

“…Understanding the effects of nitrogen (N) deposition on plant functional traits can provide insights into their adaptation strategies. We conducted an N…”
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LOT: A Story-Centric Benchmark for Evaluating Chinese Long Text Understanding and Generation by Guan, Jian, Feng, Zhuoer, Chen, Yamei, He, Ruilin, Mao, Xiaoxi, Fan, Changjie, Huang, Minlie

“…Standard multi-task benchmarks are essential for developing pretraining models that can generalize to various downstream tasks. Existing benchmarks for natural…”
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PI3K/mTOR inhibitors promote G6PD autophagic degradation and exacerbate oxidative stress damage to radiosensitize small cell lung cancer by Deng, Huan, Chen, Yamei, Wang, Li, Zhang, Yibi, Hang, Qingqing, Li, Peijing, Zhang, Peng, Ji, Jing, Song, Hai, Chen, Ming, Jin, Ying

“…Our previous study revealed that PI3K/AKT/mTOR signaling was associated with SCLC radioresistance. SBC2 cells were used as primary radioresistance models,…”
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Effects of Soil Fauna on the Home-Field Advantage of Litter Total Phenol and Condensed Tannin Decomposition by Lingyuan Lei, Jing Zeng, Quanwei Liu, Lijuan Luo, Zhiliang Ma, Yamei Chen, Yang Liu

“…Soil fauna play a vital role in contributing to the home-field advantage (HFA: litter decomposes faster in its natural habitat than elsewhere) during litter…”
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A chlorin e6 derivative-mediated photodynamic therapy for mild to moderate acne: A prospective, single-blind, randomized, split-face controlled study by Zhang, Haiyan, Zhao, Yan, Tao, Hui, Feng, Chunmei, Wang, Peiru, Zhang, Linglin, Liu, Xiaojing, Chen, Yamei, Wang, Xiuli

“…•The chlorin e6 derivative itself is a photosensitizer and does not require absorption, transformation, or metabolism to function.•STBF-PDT is a safe and…”
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Fast depth intra coding based on texture feature and spatio‐temporal correlation in 3D‐HEVC by Li, Tiansong, Yu, Li, Wang, Hongkui, Chen, Yamei

“…To alleviate the computation burden of the depth intra coding in 3D‐HEVC, a complexity reduction scheme based on texture feature and spatio‐temporal…”
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Colloidal Filterable Bacteria Enhance Ammonia Nitrogen Enrichment in River Colloids under Different Turbidity Conditions: Bacterial Diversity, Assembly Mechanism, and Nitrogen Transformation by Niu, Lihua, Chen, Rui, Li, Yi, Chen, Yamei, Zhang, Wenlong, Zhang, Huanjun, Wang, Longfei

“…Turbidity has been one of the most typical problems in urban rivers, accompanied by eutrophication. Though the colloid is a nonnegligible factor associated…”
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