Search Results - "Chen, Y. D. I."

Bidirectional Mendelian randomization to explore the causal relationships between body mass index and polycystic ovary syndrome by Brower, M A, Hai, Y, Jones, M R, Guo, X, Chen, Y -D I, Rotter, J I, Krauss, R M, Legro, R S, Azziz, R, Goodarzi, M O

“…Abstract STUDY QUESTION What are the causal relationships between polycystic ovary syndrome (PCOS) and body mass index (BMI)? SUMMARY ANSWER Bidirectional…”
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Systematic evaluation of validated type 2 diabetes and glycaemic trait loci for association with insulin clearance by Goodarzi, M. O., Guo, X., Cui, J., Jones, M. R., Haritunians, T., Xiang, A. H., Chen, Y.-D. I., Taylor, K. D., Buchanan, T. A., Hsueh, W. A., Raffel, L. J., Rotter, J. I.

“…Aims/hypothesis Insulin clearance is a highly heritable trait, for which few quantitative trait loci have been discovered. We sought to determine whether…”
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Insulin clearance: confirmation as a highly heritable trait, and genome-wide linkage analysis by Guo, X., Cui, J., Jones, M. R., Haritunians, T., Xiang, A. H., Chen, Y.-D. I., Taylor, K. D., Buchanan, T. A., Davis, R. C., Hsueh, W. A., Raffel, L. J., Rotter, J. I., Goodarzi, M. O.

“…Aims/hypothesis We have previously documented a high heritability of insulin clearance in a Hispanic cohort. Here, our goal was to confirm the high…”
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genome-wide association scan for acute insulin response to glucose in Hispanic-Americans: the Insulin Resistance Atherosclerosis Family Study (IRAS FS) by Rich, S. S, Goodarzi, M. O, Palmer, N. D, Langefeld, C. D, Ziegler, J, Haffner, S. M, Bryer-Ash, M, Norris, J. M, Taylor, K. D, Haritunians, T, Rotter, J. I, Chen, Y.-D. I, Wagenknecht, L. E, Bowden, D. W, Bergman, R. N

“…Aims/hypothesis This study sought to identify genes and regions in the human genome that are associated with the acute insulin response to glucose (AIRg), an…”
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Statin-induced expression change of INSIG1 in lymphoblastoid cell lines correlates with plasma triglyceride statin response in a sex-specific manner by Theusch, E, Kim, K, Stevens, K, Smith, J D, Chen, Y -D I, Rotter, J I, Nickerson, D A, Medina, M W

“…Statins are widely prescribed to lower plasma low-density lipoprotein (LDL) cholesterol levels. They also modestly reduce plasma triglyceride (TG), an…”
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Diagnosis of insulin resistance in hypertensive patients by the metabolic syndrome: AHA vs. IDF definitions by Hwu, C-M, Hsiung, C A, Wu, K-D, Lee, W-J, Shih, K-C, Grove, J, Chen, Y-D I, Rodriguez, B L, Curb, J D

“…Subjects with the metabolic syndrome are accompanied by insulin resistance (IR). However, it is not clear how well the newly defined metabolic syndrome…”
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Transferability and fine-mapping of glucose and insulin quantitative trait loci across populations: CARe, the Candidate Gene Association Resource by Liu, C. -T., Ng, M. C. Y., Rybin, D., Adeyemo, A., Bielinski, S. J., Boerwinkle, E., Borecki, I., Cade, B., Chen, Y. D. I., Djousse, L., Fornage, M., Goodarzi, M. O., Grant, S. F. A., Guo, X., Harris, T., Kabagambe, E., Kizer, J. R., Liu, Y., Lunetta, K. L., Mukamal, K., Nettleton, J. A., Pankow, J. S., Patel, S. R., Ramos, E., Rasmussen-Torvik, L., Rich, S. S., Rotimi, C. N., Sarpong, D., Shriner, D., Sims, M., Zmuda, J. M., Redline, S., Kao, W. H., Siscovick, D., Florez, J. C., Rotter, J. I., Dupuis, J., Wilson, J. G., Bowden, D. W., Meigs, J. B.

“…Aims/hypothesis Hyperglycaemia disproportionately affects African-Americans (AfAs). We tested the transferability of 18 single-nucleotide polymorphisms (SNPs)…”
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Sagittal abdominal diameter is associated with insulin sensitivity in Chinese hypertensive patients and their siblings by HWU, C.-M, HSIAO, C.-F, SHEU, W. H. H, PEI, D, TAI, T.-Y, QUERTERMOUS, T, RODRIGUEZ, B, PRATT, R, CHEN, Y.-D. I, HO, L.-T

“…The purpose of the study is to observe the relation between anthropometric measurements, focusing on sagittal abdominal diameter (SAD), and insulin sensitivity…”
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Demonstration of a relationship between white blood cell count, insulin resistance, and several risk factors for coronary heart disease in women by Facchini, F, Hollenbeck, C B, Chen, Y N, Chen, Y D, Reaven, G M

“…In order to evaluate the relationship between peripheral white blood cell (WBC) count, insulin-mediated glucose uptake, and several risk factors for coronary…”
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Genome-wide scans for heritability of fasting serum insulin and glucose concentrations in hypertensive families by FREEDMAN, B. I, RICH, S. S, BECK, S. R, SALE, M. M, HEISS, G, DJOUSSE, L, PANKOW, J. S, PROVINCE, M. A, RAO, D. C, LEWIS, C. E, CHEN, Y. D. I

“…The heritability of fasting serum insulin and glucose concentrations in non-diabetic members of multiplex hypertensive families is unknown. We calculated the…”
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Resistance to insulin suppression of plasma free fatty acid concentrations and insulin stimulation of glucose uptake in noninsulin-dependent diabetes mellitus by Chen, Y D, Golay, A, Swislocki, A L, Reaven, G M

“…The ability of insulin to stimulate tissue glucose uptake and lower plasma FFA concentrations was quantified in 12 individuals with normal glucose tolerance…”
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Further evidence for a central role of adipose tissue in the antihyperglycemic effect of metformin by ABBASI, F, CARANTONI, M, CHEN, Y.-D. I, REAVEN, G. M

“…Further evidence for a central role of adipose tissue in the antihyperglycemic effect of metformin. F Abbasi , M Carantoni , Y D Chen and G M Reaven Department…”
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Surrogate estimates of insulin sensitivity in subjects with hypertension by HWU, C. M, HSIAO, C. F, GROVE, J, HUNG, Y. J, CHUANG, L. M, CHEN, Y. T, CURB, J. D, CHEN, Y. D. I, RODRIGUEZ, B, HO, L. T

“…The purpose of the study is to compare surrogate estimates of insulin sensitivity with a directly measured insulin sensitivity index, steady-state plasma…”
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Genome-wide meta-analysis of variant-by-diuretic interactions as modulators of lipid traits in persons of European and African ancestry by de las Fuentes, L., Sung, Y. J., Sitlani, C. M., Avery, C. L., Bartz, T. M., Keyser, C. de, Evans, D. S., Li, X., Musani, S. K., Ruiter, R., Smith, A. V., Sun, F., Trompet, S., Xu, H., Arnett, D. K., Bis, J. C., Broeckel, U., Busch, E. L., Chen, Y.-D. I., Correa, A., Cummings, S. R., Floyd, J. S., Ford, I., Guo, X., Harris, T. B., Ikram, M. A., Lange, L., Launer, L. J., Reiner, A. P., Schwander, K., Smith, N. L., Sotoodehnia, N., Stewart, J. D., Stott, D. J., Stürmer, T., Taylor, K. D., Uitterlinden, A., Vasan, R. S., Wiggins, K. L., Cupples, L. A., Gudnason, V., Heckbert, S. R., Jukema, J. W., Liu, Y., Psaty, B. M., Rao, D. C., Rotter, J. I., Stricker, B., Wilson, J. G., Whitsel, E. A.

“…Hypertension (HTN) is a significant risk factor for cardiovascular morbidity and mortality. Metabolic abnormalities, including adverse cholesterol and…”
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Lysine-Specific Demethylase 1: An Epigenetic Regulator of Salt-Sensitive Hypertension by Williams, Jonathan S., Chamarthi, Bindu, Goodarzi, Mark O., Pojoga, Luminita H., Sun, Bei, Garza, Amanda E., Raby, Benjamin A., Adler, Gail K., Hopkins, Paul N., Brown, Nancy J., Jeunemaitre, Xavier, Ferri, Claudio, Fang, Rui, Leonor, Thiago, Cui, Jinrui, Guo, Xiuqing, Taylor, Kent D., Chen, Yii-Der Ida, Xiang, Anny, Raffel, Leslie J., Buchanan, Thomas A., Rotter, Jerome I., Williams, Gordon H., Shi, Yujiang

“…Background Hypertension (HTN) represents a complex heritable disease in which environmental factors may directly affect gene function via epigenetic…”
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Relations Between Deletion Polymorphism of the Angiotensin-Converting Enzyme Gene and Insulin Resistance, Glucose Intolerance, Hyperinsulinemia, and Dyslipidemia by Katsuya, Tomohiro, Horiuchi, Masatsugu, Chen, Y.-D.I, Koike, George, Pratt, Richard E, Dzau, Victor J, Reaven, Gerald M

“…Recent reports have shown that the frequency of the homozygous deletion genotype (DD) of the angiotensin-converting enzyme (ACE) gene is highly associated with…”
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Resistance to insulin-stimulated-glucose uptake in patients with hypertension by Shen, D C, Shieh, S M, Fuh, M M, Wu, D A, Chen, Y D, Reaven, G M

“…Plasma glucose and insulin responses to a glucose challenge and insulin-stimulated glucose uptake were measured in 24 age-, weight-, and sex-matched Chinese…”
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The effect of surgical stress on insulin sensitivity, glucose effectiveness and acute insulin response to glucose load by PEI, D, CHEN, T.-W, KUO, Y.-L, HUNG, Y.-J, HSIEH, C.-H, WU, L.-Y, CHANG, J.-B, CHOU, T.-C, CHEN, Y.-D. I, KUO, S.-W

“…Hyperglycemia after stress is a very common clinical phenomenon. It is generally hypothesized that the underlying cause is a neuroendocrine-mediated…”
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Lipoprotein receptor-related protein 1 variants and dietary fatty acids: meta-analysis of European origin and African American studies by Smith, C E, Ngwa, J, Tanaka, T, Qi, Q, Wojczynski, M K, Lemaitre, R N, Anderson, J S, Manichaikul, A, Mikkilä, V, van Rooij, F J A, Ye, Z, Bandinelli, S, Frazier-Wood, A C, Houston, D K, Hu, F, Langenberg, C, McKeown, N M, Mozaffarian, D, North, K E, Viikari, J, Zillikens, M C, Djoussé, L, Hofman, A, Kähönen, M, Kabagambe, E K, Loos, R J F, Saylor, G B, Forouhi, N G, Liu, Y, Mukamal, K J, Chen, Y-DI, Tsai, M Y, Uitterlinden, A G, Raitakari, O, van Duijn, C M, Arnett, D K, Borecki, I B, Cupples, L A, Ferrucci, L, Kritchevsky, S B, Lehtimäki, T, Qi, Lu, Rotter, J I, Siscovick, D S, Wareham, N J, Witteman, J C M, Ordovás, J M, Nettleton, J A

“…Objective: Low-density lipoprotein-related receptor protein 1 (LRP1) is a multi-functional endocytic receptor and signaling molecule that is expressed in…”
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Statin-induced expression change of INSIG1 in lymphoblastoid cell lines correlates with plasma triglyceride statin response in a sex-specific manner by Theusch, E, Kim, K, Stevens, K, Smith, J D, Chen, Y-D I, Rotter, J I, Nickerson, D A, Medina, M W

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