Search Results - "Chen, Xin Jie"
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Visible-light-initiated malic acid-promoted cascade coupling/cyclization of aromatic amines and KSCN to 2-aminobenzothiazoles without photocatalyst
Published in Chinese chemical letters (01-07-2020)“…A simple and practical method for the synthesis of 2-aminobenzothiazoles through visible-light-initiated malic acid-promoted cascade coupling/cyclization of…”
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The organization and inheritance of the mitochondrial genome
Published in Nature reviews. Genetics (01-11-2005)“…Mitochondrial DNA (mtDNA) encodes essential components of the cellular energy-producing apparatus, and lesions in mtDNA and mitochondrial dysfunction…”
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Caffeine ameliorates the metabolic syndrome in diet-induced obese mice through regulating the gut microbiota and serum metabolism
Published in Diabetology and metabolic syndrome (08-03-2023)“…Obesity is associated with gut microbiota disorders, which has been related to developing metabolic syndromes. The research aims to investigate the effects of…”
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Analysis of Lung Adenocarcinoma Subtypes Based on Immune Signatures Identifies Clinical Implications for Cancer Therapy
Published in Molecular therapy. Oncolytics (26-06-2020)“…Lung cancer is the most common cause of cancer deaths worldwide, and lung adenocarcinoma (LUAD) is the most common histological subtype. However, the…”
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A cytosolic network suppressing mitochondria-mediated proteostatic stress and cell death
Published in Nature (London) (27-08-2015)“…A new pathway of mitochondria-mediated cell death termed mitochondrial precursor over-accumulation stress (mPOS) is identified that could explain the link…”
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1,2-Diethoxyethane catalyzed oxidative cleavage of gem-disubstituted aromatic alkenes to ketones under minimal solvent conditions
Published in Chinese chemical letters (01-07-2020)“…By employing 1,2-diethoxyethane as a catalyst and ambient air as an oxidant, an efficient protocol for the construction of various aryl-alkyl and diaryl…”
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Identification of a t(X;17)(q28;q21) generating a KANSL1‐MTCP1 gene fusion leading to dysregulated expression of MTCP1 in acute myeloid leukemia
Published in Genes chromosomes & cancer (01-07-2020)“…Chromosomal translocations and generating fusion genes are closely associated with disease initiation and progression in acute myeloid leukemia (AML). In this…”
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Risk analysis of depression among adult patients with epilepsy of different sex: a retrospective single-center study from China
Published in Frontiers in psychiatry (04-12-2023)“…To determine sex differences in the prevalence of depression and assess the risk factors for depression among adult patients with epilepsy from the Dali area…”
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Aconitase couples metabolic regulation to mitochondrial DNA maintenance
Published in Science (American Association for the Advancement of Science) (04-02-2005)“…Mitochondrial DNA (mtDNA) is essential for cells to maintain respiratory competency and is inherited as a protein-DNA complex called the nucleoid. We have…”
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Evolving of treatment paradigms and challenges in acute promyelocytic leukaemia: A real-world analysis of 1105 patients over the last three decades
Published in Translational oncology (01-11-2022)“…•The early death rate of APL patients decreased over time with the introduction of ATO.•Overall and disease-free survival improved remarkably over the last…”
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TGF-β1 promotes human breast cancer angiogenesis and malignant behavior by regulating endothelial-mesenchymal transition
Published in Frontiers in oncology (16-11-2022)“…Endothelial-mesenchymal transition (EndMT) is an important process of angiogenesis, which plays a significant role in in tumor invasion and metastasis, while…”
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Potentially Overestimated Efficacy of Nanoparticle Albumin-bound Paclitaxel compared with Solvent-based Paclitaxel in Breast Cancer: A Systemic Review and Meta-analysis
Published in Journal of Cancer (01-01-2021)“…Background: Nanoparticle albumin-bound paclitaxel (nab-PTX) has exhibited clinical efficacy in breast cancer treatment, but toxicities can be yielded more at…”
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PALLD Regulates Phagocytosis by Enabling Timely Actin Polymerization and Depolymerization
Published in The Journal of immunology (1950) (01-09-2017)“…PALLD is an actin cross-linker supporting cellular mechanical tension. However, its involvement in the regulation of phagocytosis, a cellular activity…”
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Mechanism of Homologous Recombination and Implications for Aging-Related Deletions in Mitochondrial DNA
Published in Microbiology and Molecular Biology Reviews (01-09-2013)“…Classifications Services MMBR Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Heme oxygenase-1 participates in the resolution of seawater drowning-induced acute respiratory distress syndrome
Published in Respiratory physiology & neurobiology (01-01-2018)“…[Display omitted] •Seawater inhalation induced the mild acute respiratory distress syndrome.•The seawater drowning-induced acute respiratory distress syndrome…”
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Cross-linking fluorene copolymers via thiol-ene click chemistry
Published in Synthetic metals (01-12-2021)“…A series of 9,9-bis(allyl)fluorene copolymers (PFAF) with allyl groups on the side chain were synthesized by Suzuki coupling reaction. The cross-linked…”
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Prenatal diagnosis of hemivertebrae—A likely association with 7q deletion
Published in Taiwanese journal of obstetrics & gynecology (01-02-2016)“…Abstract Objective This study aims to investigate the possible cause of a prenatal case of hemivertebrae with a 7q terminal deletion. Case Report This case…”
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Adenine Nucleotide Translocase, Mitochondrial Stress, and Degenerative Cell Death
Published in Oxidative medicine and cellular longevity (01-01-2013)“…Mitochondria are intracellular organelles involved in ATP synthesis, apoptosis, calcium signaling, metabolism, and the synthesis of critical metabolic…”
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FLT3 inhibition upregulates HDAC8 via FOXO to inactivate p53 and promote maintenance of FLT3-ITD+ acute myeloid leukemia
Published in Blood (23-04-2020)“…Internal tandem duplication (ITD) mutations within the FMS-like receptor tyrosine kinase-3 (FLT3) can be found in up to 25% to 30% of acute myeloid leukemia…”
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Homoharringtonine deregulates MYC transcriptional expression by directly binding NF-κB repressing factor
Published in Proceedings of the National Academy of Sciences - PNAS (05-02-2019)“…Homoharringtonine (HHT), a known protein synthesis inhibitor, has an anti-myeloid leukemia effect and potentiates the therapeutic efficacy of…”
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