Search Results - "Chen, Xiangding"
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Roles of miR-196a and miR-196b in Zebrafish Motor Function
Published in Biomolecules (Basel, Switzerland) (01-03-2023)“…The exertion of motor function depends on various tissues, such as bones and muscles. miR-196 has been widely studied in cancer and other fields, but its…”
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Loss of Wnt16 Leads to Skeletal Deformities and Downregulation of Bone Developmental Pathway in Zebrafish
Published in International journal of molecular sciences (01-07-2021)“…Wingless-type MMTV integration site family, member 16 (wnt16), is a wnt ligand that participates in the regulation of vertebrate skeletal development. Studies…”
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Effect of esketamine combined with dexmedetomidine on delirium in sedation for mechanically ventilated ICU patients: protocol for a nested substudy within a randomized controlled trial
Published in Current controlled trials in cardiovascular medicine (02-07-2024)“…Use of sedatives and analgesics is associated with the occurrence of delirium in critically ill patients receiving mechanical ventilation. Dexmedetomidine…”
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Transcriptomic analysis reveals shared gene signatures and molecular mechanisms between obesity and periodontitis
Published in Frontiers in immunology (29-03-2023)“…Both obesity (OB) and periodontitis (PD) are chronic non-communicable diseases, and numerous epidemiological studies have demonstrated the association between…”
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Isovitexin reduces carcinogenicity and stemness in hepatic carcinoma stem-like cells by modulating MnSOD and FoxM1
Published in Journal of experimental & clinical cancer research (17-06-2019)“…Manganese superoxide dismutase (MnSOD) upregulating FoxM1 have previously been demonstrated promoting lung cancer stemness. Isovitexin exhibits antitumor…”
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How is mRNA expression predictive for protein expression? A correlation study on human circulating monocytes
Published in Acta biochimica et biophysica Sinica (01-05-2008)“…A key assumption in studying mRNA expression is that it is informative in the prediction of protein expression. However, only limited studies have explored the…”
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Zebrafish myo7aa affects congenital hearing by regulating Rho-GTPase signaling
Published in Frontiers in molecular neuroscience (15-07-2024)“…, the homolog of the human Usher 1B syndrome pathogenic gene, , plays an important role in stereociliary development and maintenance, therefore, is critical…”
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Retraction Note: Isovitexin reduces carcinogenicity and stemness in hepatic carcinoma stem-like cells by modulating MnSOD and FoxM1
Published in Journal of experimental & clinical cancer research (30-08-2022)“…This article has been retracted. Please see the Retraction Notice for more detail: https://doi.org/10.1186/s13046-019-1244-6…”
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Investigating the impact of human blood metabolites on the Sepsis development and progression: a study utilizing two-sample Mendelian randomization
Published in Frontiers in medicine (2023)“…Existing data suggests a potential link between human blood metabolites and sepsis, yet the precise cause-and-effect relationship remains elusive. By using a…”
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A trans-ethnic two-stage polygenetic scoring analysis detects genetic correlation between osteoporosis and schizophrenia
Published in Clinical and translational medicine (27-02-2020)“…Backgrounds To explore the genetic correlation between schizophrenia (SCZ) and osteoporosis (OP). Design, setting, participants, measurements We conducted a…”
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Bivariate genome-wide association study suggests fatty acid desaturase genes and cadherin DCHS2 for variation of both compressive strength index and appendicular lean mass in males
Published in Bone (New York, N.Y.) (01-12-2012)“…Abstract Compressive strength index (CSI) is a newly established index for predicting hip fracture, the most serious consequence of osteoporosis. Appendicular…”
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Exploring the genetic characteristics of 93-11 and Nipponbare recombination inbred lines based on the GoldenGate SNP assay
Published in Science China. Life sciences (01-07-2016)“…Understanding genetic characteristics in rice populations will facilitate exploring evolutionary mechanisms and gene cloning. Numerous molecular markers have…”
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8-Bromo-7-methoxychrysin-blocked STAT3/ Twist axis inhibits the sternness of cancer stem cell-like cell originated from SMMC-7721 cells
Published in 生物化学与生物物理学报:英文版 (2017)“…Signal transducer and activator of transcription 3 (STAT3) is a member of the family of latent cytoplasmic transcriptional factors that could regulate cell…”
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A genome wide association study between copy number variation (CNV) and human height in Chinese population
Published in Journal of genetics and genomics (01-12-2010)“…Copy number variation (CNV) is a type of genetic variation which may have important roles in phenotypic variability and disease susceptibility. To hunt for…”
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Frequency, duration, severity of energy drought and its propagation in hydro-wind-photovoltaic complementary systems
Published in Renewable energy (01-09-2024)“…Analyzing low-renewable-output events, termed “energy droughts” is crucial for renewable energy systems. However, due to the challenges in hydropower…”
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Inactivation of AKT, ERK and NF-κB by genistein derivative, 7-difluoromethoxyl-5,4′-di-n-octylygenistein, reduces ovarian carcinoma oncogenicity
Published in Oncology reports (01-08-2017)“…Cancer stem cells (CSCs) have central functions in cancer formation and development. Aberrant expression of AKT, ERK and NF-κB signaling pathways have been…”
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MAVS of triploid hybrid of red crucian carp and allotetraploid possesses the improved antiviral activity compared with the counterparts of its parents
Published in Fish & shellfish immunology (01-06-2019)“…Triploid hybrid (3n = 150) of red crucian carp (♀, 2n = 100) and allotetraploid (♂, 4n = 200) presents the obviously stronger disease resistance than its…”
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Multistage genome-wide association meta-analyses identified two new loci for bone mineral density
Published in Human molecular genetics (01-04-2014)“…Aiming to identify novel genetic variants and to confirm previously identified genetic variants associated with bone mineral density (BMD), we conducted a…”
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Genistein inhibits lung cancer cell stem-like characteristics by modulating MnSOD and FoxM1 expression
Published in Oncology letters (01-09-2020)“…Manganese superoxide dismutase (MnSOD) promotes invasive and migratory activities by upregulating Forkhead box protein M1 (FoxM1) expression. The present study…”
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