Search Results - "Chen, Xiang Mei"
-
1
miR-335 and miR-34a Promote Renal Senescence by Suppressing Mitochondrial Antioxidative Enzymes
Published in Journal of the American Society of Nephrology (01-07-2011)“…The molecular basis for aging of the kidney is not well understood. MicroRNAs (miRNAs) contribute to processes such as development, differentiation, and…”
Get full text
Journal Article -
2
Energy restriction in renal protection
Published in British journal of nutrition (28-11-2018)“…Energy restriction (ER) has been widely studied as a novel intervention, and its ability to prolong life has been fully demonstrated. For example, ER can…”
Get full text
Journal Article -
3
Ginsenoside Rb1 alleviates diabetic kidney podocyte injury by inhibiting aldose reductase activity
Published in Acta pharmacologica Sinica (01-02-2022)“…Panax notoginseng , a traditional Chinese medicine, exerts beneficial effect on diabetic kidney disease (DKD), but its mechanism is not well clarified. In this…”
Get full text
Journal Article -
4
Renal Endothelial Cell‐Targeted Extracellular Vesicles Protect the Kidney from Ischemic Injury
Published in Advanced science (01-01-2023)“…Endothelial cell injury plays a critical part in ischemic acute kidney injury (AKI) and participates in the progression of AKI. Targeting renal endothelial…”
Get full text
Journal Article -
5
Icariin ameliorates glycolytic dysfunction in Alzheimer's disease models by activating the Wnt/β-catenin signaling pathway
Published in The FEBS journal (01-05-2024)“…It was reported that the Wnt/β-catenin pathway is involved in the regulation of aerobic glycolysis and that brain glycolytic dysfunction results in the…”
Get full text
Journal Article -
6
Clinical and pathological factors associated with progression of diabetic nephropathy
Published in Nephrology (Carlton, Vic.) (01-12-2017)“…Summary at a Glance This article reviews the values and limitations of some factors in the development and progression of diabetic kidney disease. ABSTRACT As…”
Get full text
Journal Article -
7
Assessment of the Added Value of Intravoxel Incoherent Motion Diffusion-Weighted MR Imaging in Identifying Non-Diabetic Renal Disease in Patients With Type 2 Diabetes Mellitus
Published in Journal of magnetic resonance imaging (01-05-2024)“…Identification of non-diabetic renal disease (NDRD) in patients with type 2 diabetes mellitus (T2DM) may help tailor treatment. Intravoxel incoherent motion…”
Get full text
Journal Article -
8
Risk factors for mortality in elderly haemodialysis patients: a systematic review and meta-analysis
Published in BMC nephrology (31-08-2020)“…Older haemodialysis patients accompany a high burden of functional impairment, limited life expectancy, and healthcare utilization. This meta-analysis aimed to…”
Get full text
Journal Article -
9
Single-cell RNA sequencing data suggest a role for angiotensin-converting enzyme 2 in kidney impairment in patients infected with 2019-novel coronavirus
Published in Chinese medical journal (05-05-2020)“…[...]ACE2 was found to be expressed predominantly in tubular precursors of the kidney of the fetal case [Supplemental Figure 1, http://links.lww.com/CM9/A212]…”
Get full text
Journal Article -
10
Identification of key genes and pathways in diabetic nephropathy by bioinformatics analysis
Published in Journal of diabetes investigation (01-07-2019)“…Aims/Introduction The aim of the present study was to identify candidate differentially expressed genes (DEGs) and pathways using bioinformatics analysis, and…”
Get full text
Journal Article -
11
Dual gRNAs guided CRISPR/Cas9 system inhibits hepatitis B virus replication
Published in World journal of gastroenterology : WJG (28-08-2015)“…AIM: To screen and investigate the effective g RNAs against hepatitis B virus(HBV) of genotypes A-D.METHODS: A total of 15 g RNAs against HBV of genotypes A-D…”
Get full text
Journal Article -
12
Genetically engineered mesenchymal stem cells as a nitric oxide reservoir for acute kidney injury therapy
Published in eLife (11-09-2023)“…Nitric oxide (NO), as a gaseous therapeutic agent, shows great potential for the treatment of many kinds of diseases. Although various NO delivery systems have…”
Get full text
Journal Article -
13
Blood coagulation system in patients with chronic kidney disease: a prospective observational study
Published in BMJ open (01-05-2017)“…ObjectivesThromboembolic events are the major factor affecting the prognosis of patients with chronic kidney disease (CKD). Haemostatic alterations are…”
Get full text
Journal Article -
14
miRNAs in stem cell-derived extracellular vesicles for acute kidney injury treatment: comprehensive review of preclinical studies
Published in Stem cell research & therapy (03-09-2019)“…Stem cell therapy has been applied in many fields. Basic and clinical studies on stem cell therapy for acute kidney injury (AKI) have been conducted. Stem…”
Get full text
Journal Article -
15
Receptor for advanced glycation end-products promotes premature senescence of proximal tubular epithelial cells via activation of endoplasmic reticulum stress-dependent p21 signaling
Published in Cellular signalling (01-01-2014)“…Premature senescence is a key process in the progression of diabetic nephropathy (DN). In our study, we hypothesized that receptors for advanced glycation…”
Get full text
Journal Article -
16
Identifying parameters to distinguish non-diabetic renal diseases from diabetic nephropathy in patients with type 2 diabetes mellitus: a meta-analysis
Published in PloS one (14-05-2013)“…Renal injuries in patients with diabetes include diabetic nephropathy (DN) and non-diabetic renal diseases (NDRD). The value of a clinical diagnosis of DN and…”
Get full text
Journal Article -
17
Impact of ER stress-regulated ATF4/p16 signaling on the premature senescence of renal tubular epithelial cells in diabetic nephropathy
Published in American Journal of Physiology: Cell Physiology (15-04-2015)“…Premature senescence is an important event during diabetic nephropathy (DN) progression. Here, we investigated the role of endoplasmic reticulum (ER)…”
Get more information
Journal Article -
18
Use of thermal imaging and Fourier transform infrared spectroscopy for the pre-symptomatic detection of cucumber downy mildew
Published in European journal of plant pathology (01-10-2019)“…Most cultivars of cucumber are susceptible to Pseudoperonospora cubensis , the causal agent of cucurbit downy mildew. This study aimed to evaluate the…”
Get full text
Journal Article -
19
Selection of urinary sediment miRNAs as specific biomarkers of IgA nephropathy
Published in Scientific reports (22-03-2016)“…The miRNAs in urinary sediment are easy to obtain, which provides a new approach to searching for non-invasive biomarkers of IgA nephropathy (IgAN). Compared…”
Get full text
Journal Article -
20
Incidence, risk factors and prognosis of acute kidney injury in patients treated with immune checkpoint inhibitors: a retrospective study
Published in Scientific reports (05-11-2022)“…Immune checkpoint inhibitors (ICIs) change the prognosis of many cancer patients. With the increasing use of ICIs, immune-related adverse events are occurring,…”
Get full text
Journal Article