Search Results - "Chen, Xiang Mei"

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  1. 1

    miR-335 and miR-34a Promote Renal Senescence by Suppressing Mitochondrial Antioxidative Enzymes by BAI, Xue-Yuan, YUXIANG MA, RUI DING, BO FU, SUOZHU SHI, CHEN, Xiang-Mei

    “…The molecular basis for aging of the kidney is not well understood. MicroRNAs (miRNAs) contribute to processes such as development, differentiation, and…”
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    Journal Article
  2. 2

    Energy restriction in renal protection by Wang, Si-Yang, Cai, Guang-Yan, Chen, Xiang-Mei

    Published in British journal of nutrition (28-11-2018)
    “…Energy restriction (ER) has been widely studied as a novel intervention, and its ability to prolong life has been fully demonstrated. For example, ER can…”
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  3. 3

    Ginsenoside Rb1 alleviates diabetic kidney podocyte injury by inhibiting aldose reductase activity by He, Jia-yi, Hong, Quan, Chen, Bi-xia, Cui, Shao-yuan, Liu, Ran, Cai, Guang-yan, Guo, Jiao, Chen, Xiang-mei

    Published in Acta pharmacologica Sinica (01-02-2022)
    “…Panax notoginseng , a traditional Chinese medicine, exerts beneficial effect on diabetic kidney disease (DKD), but its mechanism is not well clarified. In this…”
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  4. 4

    Renal Endothelial Cell‐Targeted Extracellular Vesicles Protect the Kidney from Ischemic Injury by Zhang, Kaiyue, Li, Rongrong, Chen, Xiaoniao, Yan, Hongyu, Li, Huifang, Zhao, Xiaotong, Huang, Haoyan, Chen, Shang, Liu, Yue, Wang, Kai, Han, Zhibo, Han, Zhong‐Chao, Kong, Deling, Chen, XiangMei, Li, Zongjin

    Published in Advanced science (01-01-2023)
    “…Endothelial cell injury plays a critical part in ischemic acute kidney injury (AKI) and participates in the progression of AKI. Targeting renal endothelial…”
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  5. 5

    Icariin ameliorates glycolytic dysfunction in Alzheimer's disease models by activating the Wnt/β-catenin signaling pathway by Liu, Ju, Wei, Ai-Hong, Liu, Ting-Ting, Ji, Xin-Hao, Zhang, Ying, Yan, Fei, Chen, Mei-Xiang, Hu, Jin-Bo, Zhou, Shao-Yu, Shi, Jing-Shan, Jin, Hai, Jin, Feng

    Published in The FEBS journal (01-05-2024)
    “…It was reported that the Wnt/β-catenin pathway is involved in the regulation of aerobic glycolysis and that brain glycolytic dysfunction results in the…”
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  6. 6

    Clinical and pathological factors associated with progression of diabetic nephropathy by Liang, Shuang, Cai, Guang‐Yan, Chen, XiangMei

    Published in Nephrology (Carlton, Vic.) (01-12-2017)
    “…Summary at a Glance This article reviews the values and limitations of some factors in the development and progression of diabetic kidney disease. ABSTRACT As…”
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    Risk factors for mortality in elderly haemodialysis patients: a systematic review and meta-analysis by Song, Yu-Huan, Cai, Guang-Yan, Xiao, Yue-Fei, Chen, Xiang-Mei

    Published in BMC nephrology (31-08-2020)
    “…Older haemodialysis patients accompany a high burden of functional impairment, limited life expectancy, and healthcare utilization. This meta-analysis aimed to…”
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  9. 9

    Single-cell RNA sequencing data suggest a role for angiotensin-converting enzyme 2 in kidney impairment in patients infected with 2019-novel coronavirus by Deng, Yi-Yao, Zheng, Ying, Cai, Guang-Yan, Chen, Xiang-Mei, Hong, Quan

    Published in Chinese medical journal (05-05-2020)
    “…[...]ACE2 was found to be expressed predominantly in tubular precursors of the kidney of the fetal case [Supplemental Figure 1, http://links.lww.com/CM9/A212]…”
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  10. 10

    Identification of key genes and pathways in diabetic nephropathy by bioinformatics analysis by Geng, Xiao‐dong, Wang, Wei‐wei, Feng, Zhe, Liu, Ran, Cheng, Xiao‐long, Shen, Wan‐jun, Dong, Zhe‐yi, Cai, Guang‐yan, Chen, Xiangmei, Hong, Quan, Wu, Di

    Published in Journal of diabetes investigation (01-07-2019)
    “…Aims/Introduction The aim of the present study was to identify candidate differentially expressed genes (DEGs) and pathways using bioinformatics analysis, and…”
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  11. 11

    Dual gRNAs guided CRISPR/Cas9 system inhibits hepatitis B virus replication by Wang, Jie, Xu, Zhong-Wei, Liu, Shuang, Zhang, Rui-Yang, Ding, Shan-Long, Xie, Xiao-Meng, Long, Lu, Chen, Xiang-Mei, Zhuang, Hui, Lu, Feng-Min

    Published in World journal of gastroenterology : WJG (28-08-2015)
    “…AIM: To screen and investigate the effective g RNAs against hepatitis B virus(HBV) of genotypes A-D.METHODS: A total of 15 g RNAs against HBV of genotypes A-D…”
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  12. 12

    Genetically engineered mesenchymal stem cells as a nitric oxide reservoir for acute kidney injury therapy by Huang, Haoyan, Qian, Meng, Liu, Yue, Chen, Shang, Li, Huifang, Han, Zhibo, Han, Zhong-Chao, Chen, Xiang-Mei, Zhao, Qiang, Li, Zongjin

    Published in eLife (11-09-2023)
    “…Nitric oxide (NO), as a gaseous therapeutic agent, shows great potential for the treatment of many kinds of diseases. Although various NO delivery systems have…”
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  13. 13

    Blood coagulation system in patients with chronic kidney disease: a prospective observational study by Huang, Meng-Jie, Wei, Ri-bao, Wang, Yang, Su, Ting-yu, Di, Ping, Li, Qing-ping, Yang, Xi, Li, Ping, Chen, Xiang-mei

    Published in BMJ open (01-05-2017)
    “…ObjectivesThromboembolic events are the major factor affecting the prognosis of patients with chronic kidney disease (CKD). Haemostatic alterations are…”
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  14. 14

    miRNAs in stem cell-derived extracellular vesicles for acute kidney injury treatment: comprehensive review of preclinical studies by Wang, Si-Yang, Hong, Quan, Zhang, Chao-Yang, Yang, Yuan-Jun, Cai, Guang-Yan, Chen, Xiang-Mei

    Published in Stem cell research & therapy (03-09-2019)
    “…Stem cell therapy has been applied in many fields. Basic and clinical studies on stem cell therapy for acute kidney injury (AKI) have been conducted. Stem…”
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  15. 15

    Receptor for advanced glycation end-products promotes premature senescence of proximal tubular epithelial cells via activation of endoplasmic reticulum stress-dependent p21 signaling by Liu, Jun, Huang, Kun, Cai, Guang-Yan, Chen, Xiang-Mei, Yang, Ju-Rong, Lin, Li-Rong, Yang, Jie, Huo, Ben-Gang, Zhan, Jun, He, Ya-Ni

    Published in Cellular signalling (01-01-2014)
    “…Premature senescence is a key process in the progression of diabetic nephropathy (DN). In our study, we hypothesized that receptors for advanced glycation…”
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  16. 16

    Identifying parameters to distinguish non-diabetic renal diseases from diabetic nephropathy in patients with type 2 diabetes mellitus: a meta-analysis by Liang, Shuang, Zhang, Xue-Guang, Cai, Guang-Yan, Zhu, Han-Yu, Zhou, Jian-Hui, Wu, Jie, Chen, Pu, Lin, Shu-Peng, Qiu, Qiang, Chen, Xiang-Mei

    Published in PloS one (14-05-2013)
    “…Renal injuries in patients with diabetes include diabetic nephropathy (DN) and non-diabetic renal diseases (NDRD). The value of a clinical diagnosis of DN and…”
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  17. 17

    Impact of ER stress-regulated ATF4/p16 signaling on the premature senescence of renal tubular epithelial cells in diabetic nephropathy by Liu, Jun, Yang, Ju-Rong, Chen, Xiang-Mei, Cai, Guang-Yan, Lin, Li-Rong, He, Ya-Ni

    “…Premature senescence is an important event during diabetic nephropathy (DN) progression. Here, we investigated the role of endoplasmic reticulum (ER)…”
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  18. 18

    Use of thermal imaging and Fourier transform infrared spectroscopy for the pre-symptomatic detection of cucumber downy mildew by Wen, Dong-Mei, Chen, Mei-Xiang, Zhao, Li, Ji, Tao, Li, Ming, Yang, Xin-Ting

    Published in European journal of plant pathology (01-10-2019)
    “…Most cultivars of cucumber are susceptible to Pseudoperonospora cubensis , the causal agent of cucurbit downy mildew. This study aimed to evaluate the…”
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  19. 19

    Selection of urinary sediment miRNAs as specific biomarkers of IgA nephropathy by Duan, Zhi-Yu, Cai, Guang-yan, Bu, Ru, Lu, Yang, Hou, Kai, Chen, Xiang-Mei

    Published in Scientific reports (22-03-2016)
    “…The miRNAs in urinary sediment are easy to obtain, which provides a new approach to searching for non-invasive biomarkers of IgA nephropathy (IgAN). Compared…”
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  20. 20

    Incidence, risk factors and prognosis of acute kidney injury in patients treated with immune checkpoint inhibitors: a retrospective study by Ji, Ming-Su, Wu, Rilige, Feng, Zhe, Wang, Yuan-Da, Wang, Yong, Zhang, Li, Sun, Xue-Feng, Chen, Xiang-Mei, He, Kun-Lun, Cai, Guang-Yan

    Published in Scientific reports (05-11-2022)
    “…Immune checkpoint inhibitors (ICIs) change the prognosis of many cancer patients. With the increasing use of ICIs, immune-related adverse events are occurring,…”
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