Search Results - "Chen, WeiXian"
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Mycobacterium tuberculosis EIS gene inhibits macrophage autophagy through up-regulation of IL-10 by increasing the acetylation of histone H3
Published in Biochemical and biophysical research communications (13-05-2016)“…Autophagy plays a crucial role in the progress of Mycobacterium tuberculosis (MTB) infection. Recently, MTB enhanced intracellular survival (EIS) protein was…”
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TPPU inhibits inflammation-induced excessive autophagy to restore the osteogenic differentiation potential of stem cells and improves alveolar ridge preservation
Published in Scientific reports (28-01-2023)“…Inflammation-induced autophagy is a double-edged sword. Dysfunction of autophagy impairs the differentiation capacity of mesenchymal stem cells and enhances…”
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3
Down-regulation of long non-coding RNA AFAP1-AS1 inhibits tumor growth, promotes apoptosis and decreases metastasis in thyroid cancer
Published in Biomedicine & pharmacotherapy (01-03-2018)“…Long non-coding RNAs (lncRNAs), a new type of transcripts, play important roles in various cellular biological processes, involving tumorigenesis. Previous…”
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Aptamer recognition and proximity-induced entropy-driven circuit for enzyme-free and rapid amplified detection of platelet-derived growth factor-BB
Published in Analytica chimica acta (27-12-2019)“…Platelet-derived growth factor-BB (PDGF-BB) is currently used as a biomarker protein for cancer early diagnosis and clinical treatment. Herein, we reported a…”
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5
Microalgal polyunsaturated fatty acids: Hotspots and production techniques
Published in Frontiers in bioengineering and biotechnology (31-03-2023)“…Algae play a crucial role in the earth's primary productivity by producing not only oxygen but also a variety of high-value nutrients. One such nutrient is…”
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Liver fibrosis-derived exosomal miR-106a-5p facilitates the malignancy by targeting SAMD12 and CADM2 in hepatocellular carcinoma
Published in PloS one (25-05-2023)“…The mechanism of hepatocellular carcinoma (HCC) development induced by liver fibrosis is obscure. The objective of this study is to establish miRNAs from…”
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HBx inhibits DNA sensing signaling pathway via ubiquitination and autophagy of cGAS
Published in Virology journal (28-03-2022)“…Cyclic GMP-AMP synthase (cGAS) is a crucial DNA sensor and plays an important role in host antiviral innate immune responses. During hepatitis B virus (HBV)…”
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Optimization of culture conditions for HBV-specific T cell expansion in vitro from chronically infected patients
Published in BMC biotechnology (14-10-2024)“…Hepatitis B virus (HBV) clearance depends on an effective adaptive immune response, especially HBV-specific T cell-mediated cellular immunity; however, it is…”
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Inhibition of soluble epoxide hydrolase enhances the dentin-pulp complex regeneration mediated by crosstalk between vascular endothelial cells and dental pulp stem cells
Published in Journal of translational medicine (16-01-2024)“…Revascularization and restoration of normal pulp-dentin complex are important for tissue-engineered pulp regeneration. Recently, a unique periodontal tip-like…”
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KLRG1-expressing CD8+ T cells are exhausted and polyfunctional in patients with chronic hepatitis B
Published in PloS one (22-05-2024)“…Killer cell lectin-like receptor G1 (KLRG1) has traditionally been regarded as an inhibitory receptor of T cell exhaustion in chronic infection and…”
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11
Association between physical activity and mortality in breast cancer: a meta-analysis of cohort studies
Published in European journal of epidemiology (01-06-2014)“…Previous studies concerning the association between physical activity (PA) and mortality in breast cancer yielded mixed results. We investigated the…”
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Alpha-cyano-4-hydroxycinnamic acid alleviates renal fibrosis and inflammation in chronic kidney disease
Published in All life (Online) (31-12-2023)“…Renal fibrosis is a crucial pathological phenomenon of chronic kidney disease (CKD) that contributes to the progressive loss of renal function. Monocarboxylate…”
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13
TGF-β1 prevents blood–brain barrier damage and hemorrhagic transformation after thrombolysis in rats
Published in Experimental neurology (01-04-2015)“…Transforming growth factor-beta1 (TGF-β1) is well known to promote extracellular matrix accumulation. Recent studies demonstrated that TGF-β1 protects against…”
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A novel combined therapeutic strategy of Nano-EN-IR@Lip mediated photothermal therapy and stem cell inhibition for gastric cancer
Published in Biomedicine & pharmacotherapy (01-05-2024)“…Recurrence and metastasis of gastric cancer is a major therapeutic challenge for treatment. The presence of cancer stem cells (CSCs) is a major obstacle to the…”
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15
E-cadherin Plays a Role in Hepatitis B Virus Entry Through Affecting Glycosylated Sodium-Taurocholate Cotransporting Polypeptide Distribution
Published in Frontiers in cellular and infection microbiology (27-02-2020)“…Hepatitis B virus (HBV) infection is a major cause of chronic liver disease and hepatocellular carcinoma. Current antiviral therapy does not effectively…”
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Identification of serum β-catenin as a biomarker in patients with HBV-related liver diseases
Published in Journal of translational medicine (29-09-2018)“…Substantial evidence indicates that β-catenin is a pivotal regulator that contributes to the initiation and development of various types of diseases. Recently,…”
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Classification of the mitochondrial ribosomal protein-associated molecular subtypes and identified a serological diagnostic biomarker in hepatocellular carcinoma
Published in Frontiers in surgery (06-01-2023)“…The objective of this study was to sort out innovative molecular subtypes associated with mitochondrial ribosomal proteins (MRPs) to predict clinical therapy…”
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CCL25/CCR9 interaction promotes the malignant behavior of salivary adenoid cystic carcinoma via the PI3K/AKT signaling pathway
Published in PeerJ (San Francisco, CA) (19-08-2022)“…CC chemokine receptor 9 (CCR9), an organ-specific chemokine receptor, interacts with its exclusive ligand CCL25 to promote tumor proliferation and metastasis…”
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Pleural Fluid GSDMD Is a Novel Biomarker for the Early Differential Diagnosis of Pleural Effusion
Published in Frontiers in microbiology (07-06-2021)“…Gasdermin D (GSDMD), controlling pyroptosis in cells, has multiple physiological functions. The diagnostic role of GSDMD in pleural effusion (PE) remains…”
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Modelling the monotonic and cyclic behaviour of sands using Artificial Neural Networks
Published in EPJ Web of conferences (01-01-2021)“…In this study artificial neural networks (ANN) are used to simulate the monotonic and cyclic behaviour of sands observed in laboratory tests on Karlsruhe sand…”
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