Search Results - "Chen, Vincent S."

Weakly supervised classification of aortic valve malformations using unlabeled cardiac MRI sequences by Fries, Jason A., Varma, Paroma, Chen, Vincent S., Xiao, Ke, Tejeda, Heliodoro, Saha, Priyanka, Dunnmon, Jared, Chubb, Henry, Maskatia, Shiraz, Fiterau, Madalina, Delp, Scott, Ashley, Euan, Ré, Christopher, Priest, James R.

“…Biomedical repositories such as the UK Biobank provide increasing access to prospectively collected cardiac imaging, however these data are unlabeled, which…”
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Aβ induces astrocytic glutamate release, extrasynaptic NMDA receptor activation, and synaptic loss by Talantova, Maria, Sanz-Blasco, Sara, Zhang, Xiaofei, Xia, Peng, Akhtar, Mohd Waseem, Okamoto, Shu-ichi, Dziewczapolski, Gustavo, Nakamura, Tomohiro, Cao, Gang, Pratt, Alexander E, Kang, Yeon-Joo, Tu, Shichun, Molokanova, Elena, McKercher, Scott R, Hires, Samuel Andrew, Sason, Hagit, Stouffer, David G, Buczynski, Matthew W, Solomon, James P, Michael, Sarah, Powers, Evan T, Kelly, Jeffery W, Roberts, Amanda, Tong, Gary, Fang-Newmeyer, Traci, Parker, James, Holland, Emily A, Zhang, Dongxian, Nakanishi, Nobuki, Chen, H-S Vincent, Wolosker, Herman, Wang, Yuqiang, Parsons, Loren H, Ambasudhan, Rajesh, Masliah, Eliezer, Heinemann, Stephen F, Piña-Crespo, Juan C, Lipton, Stuart A

“…Synaptic loss is the cardinal feature linking neuropathology to cognitive decline in Alzheimer’s disease (AD). However, the mechanism of synaptic damage…”
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Balance between synaptic versus extrasynaptic NMDA receptor activity influences inclusions and neurotoxicity of mutant huntingtin by Talantova, Maria, Kaul, Marcus, Yao, Dongdong, Xia, Peng, Ehrnhoefer, Dagmar E, Zaidi, Rameez, Lipton, Stuart A, Graham, Rona K, Tong, Gary, Zhang, Dongxian, Clemente, Arjay, Okamoto, Shu-ichi, Hayden, Michael R, Pouladi, Mahmoud A, Vincent Chen, H-S

“…In a mouse model of Huntington's disease, synaptic activation of NMDA receptors induces the formation of huntingtin-containing inclusions, rendering neurons…”
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Neuroprotection by the NR3A Subunit of the NMDA Receptor by Nakanishi, Nobuki, Tu, Shichun, Shin, Yeonsook, Cui, Jiankun, Kurokawa, Toru, Zhang, Dongxian, Chen, H.-S. Vincent, Tong, Gary, Lipton, Stuart A

“…Hyperactivation of NMDA-type glutamate receptors (NMDARs) results in excitotoxicity, contributing to damage in stroke and neurodegenerative disorders. NMDARs…”
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Lentiviral vectors and protocols for creation of stable hESC lines for fluorescent tracking and drug resistance selection of cardiomyocytes by Kita-Matsuo, Hiroko, Barcova, Maria, Prigozhina, Natalie, Salomonis, Nathan, Wei, Karen, Jacot, Jeffrey G, Nelson, Brandon, Spiering, Sean, Haverslag, René, Kim, Changsung, Talantova, Maria, Bajpai, Ruchi, Calzolari, Diego, Terskikh, Alexey, McCulloch, Andrew D, Price, Jeffrey H, Conklin, Bruce R, Chen, H S Vincent, Mercola, Mark

“…Developmental, physiological and tissue engineering studies critical to the development of successful myocardial regeneration therapies require new ways to…”
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KCNQ potassium channel mutations cause cardiac arrhythmias in Drosophila that mimic the effects of aging by Ocorr, Karen, Reeves, Nick L, Wessells, Robert J, Fink, Martin, Chen, H.-S. Vincent, Akasaka, Takeshi, Yasuda, Soichiro, Metzger, Joseph M, Giles, Wayne, Posakony, James W, Bodmer, Rolf

“…Population profiles of industrialized countries show dramatic increases in cardiovascular disease with age, but the molecular and genetic basis of disease…”
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Excitatory glycine responses of CNS myelin mediated by NR1/NR3 "NMDA" receptor subunits by Piña-Crespo, Juan C, Talantova, Maria, Micu, Ileana, States, Bradley, Chen, H-S Vincent, Tu, Shichun, Nakanishi, Nobuki, Tong, Gary, Zhang, Dongxian, Heinemann, Stephen F, Zamponi, Gerald W, Stys, Peter K, Lipton, Stuart A

“…NMDA receptors are typically excited by a combination of glutamate and glycine. Here we describe excitatory responses in CNS myelin that are gated by a glycine…”
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Cardiac myocyte force development during differentiation and maturation by Jacot, Jeffrey G., Kita-Matsuo, Hiroko, Wei, Karen A., Vincent Chen, H.S., Omens, Jeffrey H., Mercola, Mark, McCulloch, Andrew D.

“…The maturation of cardiac myocytes during the immediate prenatal period coincides with changes in the mechanical properties of the extracellular matrix. We…”
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‘Other information’ as an explanatory factor for the opposite market reactions to earnings surprises by Chen, Vincent Y. S., Tiras, Samuel L.

“…Positive (negative) earnings surprises do not necessarily generate positive (negative) market reactions. In our sample from 1990 to 2010, the market reacts…”
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Scene Graph Prediction With Limited Labels by Krishna, Ranjay, Chen, Vincent, Varma, Paroma, Bernstein, Michael, Re, Christopher, Fei-Fei, Li

“…Visual knowledge bases such as Visual Genome power numerous applications in computer vision, including visual question answering and captioning, but suffer…”
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NR3A Modulates the Outer Vestibule of the "NMDA" Receptor Channel by Wada, Akira, Takahashi, Hiroto, Lipton, Stuart A, Chen, H.-S. Vincent

“…Classical NMDA receptors (NMDARs), activated by glycine and glutamate, are heteromultimers comprised of NR1 and NR2 subunits. Coexpression of the novel NR3…”
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Family ownership as a moderator between R&D investments and CEO compensation by Tsao, Shou-Min, Lin, Che-Hung, Chen, Vincent Y.S.

“…Firms can curb opportunistic managerial R&D investing behavior by increasing the sensitivity of CEO compensation to R&D investment. Using a sample of firms in…”
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Founding family ownership and innovation by Chen, Vincent Y.S., Tsao, Shou-Min, Chen, Guang-Zheng

“…This study empirically examines the extent to which family ownership affects innovation. Using a sample of Taiwanese listed firms, we find that family firms…”
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Earnings management through real activities choices of firms near the investment–speculative grade borderline by Brown, Kareen, Chen, Vincent Y.S., Kim, Myungsun

“…We examine whether manufacturing firms manage earnings through real activities for credit rating concerns. By using Standard & Poor’s Rating Service (S&P)…”
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The pharmacology of aminoadamantane nitrates by Wang, Yuqiang, Eu, Jerry, Washburn, Mark, Gong, Tong, Chen, H-S Vincent, James, W Larrick, Lipton, Stuart A, Stamler, Jonathan S, Went, Gregory T, Porter, Seth

“…Memantine, an aminodamantane, has recently been approved to treat moderate-to-severe Alzheimer's disease in the US after over 20 years on the market in Europe…”
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The Information Value of Credit Rating Action Reports: A Textual Analysis by Agarwal, Sumit, Chen, Vincent Y. S., Zhang, Weina

“…We examine whether Standard & Poor’s (S&P) credit rating action reports contain new default-related information beyond credit rating actions such as rating…”
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Cardiac Imaging of Aortic Valve Area From 34 287 UK Biobank Participants Reveals Novel Genetic Associations and Shared Genetic Comorbidity With Multiple Disease Phenotypes by Córdova-Palomera, Aldo, Tcheandjieu, Catherine, Fries, Jason A., Varma, Paroma, Chen, Vincent S., Fiterau, Madalina, Xiao, Ke, Tejeda, Heliodoro, Keavney, Bernard D., Cordell, Heather J., Tanigawa, Yosuke, Venkataraman, Guhan, Rivas, Manuel A., Ré, Christopher, Ashley, Euan, Priest, James R.

“…The aortic valve is an important determinant of cardiovascular physiology and anatomic location of common human diseases. From a sample of 34 287 white British…”
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Sex hormones affect outcome in arrhythmogenic right ventricular cardiomyopathy/dysplasia: from a stem cell derived cardiomyocyte-based model to clinical biomarkers of disease outcome by Akdis, Deniz, Saguner, Ardan M, Shah, Khooshbu, Wei, Chuanyu, Medeiros-Domingo, Argelia, von Eckardstein, Arnold, Lüscher, Thomas F, Brunckhorst, Corinna, Chen, H S Vincent, Duru, Firat

“…Arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D) is characterized by fibrofatty infiltration of the myocardium and ventricular arrhythmias…”
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Outside directors' equity incentives and strategic alliance decisions by Chan, Konan, Chen, Vincent Y.S., Huang, Yu-Fang, Liang, Jia-Wen

“…This study examines whether the proportion of equity-based compensation in outside director compensation is associated with corporate strategic alliances. We…”
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LUMA in cardiac development and function by Liu, Ying, Chen, Vincent H S, Shou, Weinian

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