Search Results - "Chen, Tianlai"

Deep learning for predicting 16S rRNA gene copy number by Miao, Jiazheng, Chen, Tianlai, Misir, Mustafa, Lin, Yajuan

“…Culture-independent 16S rRNA gene metabarcoding is a commonly used method for microbiome profiling. To achieve more quantitative cell fraction estimates, it is…”
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Algorithm selection for protein–ligand docking: strategies and analysis on ACE by Chen, Tianlai, Shu, Xiwen, Zhou, Huiyuan, Beckford, Floyd A., Misir, Mustafa

“…The present study investigates the use of algorithm selection for automatically choosing an algorithm for any given protein–ligand docking task. In drug…”
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Diagnosis and treatment of “medial to lateral diagonal injury of the elbow” in children: Concomitant medial epicondylar and radial neck fractures by Lu, Yunan, Canavese, Federico, Xia, Yongjie, Lin, Ran, Huang, Dianhua, Chen, Tianlai, Chen, Shunyou

“…Purpose: The simultaneous and ipsilateral occurrence of medial epicondylar and radial neck fractures is rare. This study evaluated the clinical and…”
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Genetically Predicted Milk Intake Increased Femoral Neck Bone Mineral Density in Women But Not in Men by Chen, Song, Zheng, Changhua, Chen, Tianlai, Chen, Jinchen, Pan, Yuancheng, Chen, Shunyou

“…Background Cow milk contains more calcium, magnesium, potassium, zinc, and phosphorus minerals. For a long time, people have believed that increasing milk…”
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Causal Association Between Tea Consumption and Bone Health: A Mendelian Randomization Study by Chen, Song, Chen, Tianlai, Chen, Yibin, Huang, Dianhua, Pan, Yuancheng, Chen, Shunyou

“…Much observational research reported that tea consumption decreases the risk of osteoarthritis (OA), rheumatoid arthritis (RA), and osteoporosis (OP) which are…”
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Titanium surfaces with biomimetic topography and copper incorporation to modulate behaviors of stem cells and oral bacteria by Li, Ruiying, Li, Shuigen, Zhang, Yi, Jin, Di, Lin, Zhiming, Tao, Xian, Chen, Tianlai, Zheng, Liyuan, Zhang, Zhisheng, Wu, Qianju

“…Insufficient osseointegration and implant-associated infection are major factors in the failure of Ti-based implants, thus spurring scientists to develop…”
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Relationship Between Plasma Vitamin C and COVID-19 Susceptibility and Severity: A Two-Sample Mendelian Randomization Study by Chen, Song, Zheng, Changhua, Chen, Tianlai, Huang, Dianhua, Pan, Yuancheng, Chen, Shunyou

“…Considering the antioxidant function of Vitamin C, also called ascorbic acid, it is widely used against viral infections such as coronavirus disease (COVID-19)…”
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Outcomes in children with delayed surgical treatment of medial humeral condyle fractures by Wu, Xinwu, Chen, Tianlai, Canavese, Federico, Lu, Yunan, Chen, Shunyou

“…Purpose Medial humeral condyle (MHC) fractures are easily overlooked in young patients. This can lead to delayed or incorrect diagnosis, resulting in delayed…”
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Generative design of therapeutics that bind and modulate protein states by Chen, Tianlai, Hong, Lauren, Yudistyra, Vivian, Vincoff, Sophia, Chatterjee, Pranam

“…Numerous therapeutic approaches have been developed to enable interrogation and modulation of protein isoforms, but often require laborious experimental…”
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Comparison of Three Internal Fixation Constructs for AO/OTA 33-A3 Distal Femoral Fractures: A Biomechanical Study by Xie, Wei, Liu, Hui, Chen, Shufen, Xu, Weizhen, Lin, Weibin, Chen, Tianlai, Zhu, Lingqi, Zhai, Wenliang, Wu, Jin

“…Background: To compare the biomechanical performance of three internal fixation constructs for AO/OTA 33-A3 distal femoral fractures. Methods: Thirty AO/OTA…”
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Nucleus Pulposus‐Targeting Nanocarriers Facilitate Mirna‐Based Therapeutics for Intervertebral Disc Degeneration by Chen, Zhonghui, Liao, Zhong, Liu, Ming, Lin, Fengfei, Chen, Shunyou, Wang, Geng, Zheng, Zhong, Liu, Boling, Li, Chaoxiong, Wang, Zheqiang, Chen, Tianlai, Huang, Hongzhe, Liao, Qi, Cui, Weiliang

“…Abstract Intervertebral disc degeneration (IDD) is a common cause of low back pain. Understanding its molecular mechanisms is the basis for developing specific…”
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SaLT&PepPr is an interface-predicting language model for designing peptide-guided protein degraders by Brixi, Garyk, Ye, Tianzheng, Hong, Lauren, Wang, Tian, Monticello, Connor, Lopez-Barbosa, Natalia, Vincoff, Sophia, Yudistyra, Vivian, Zhao, Lin, Haarer, Elena, Chen, Tianlai, Pertsemlidis, Sarah, Palepu, Kalyan, Bhat, Suhaas, Christopher, Jayani, Li, Xinning, Liu, Tong, Zhang, Sue, Petersen, Lillian, DeLisa, Matthew P., Chatterjee, Pranam

“…Protein-protein interactions (PPIs) are critical for biological processes and predicting the sites of these interactions is useful for both computational and…”
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SaLT PepPr is an interface-predicting language model for designing peptide-guided protein degraders by Garyk Brixi, Tianzheng Ye, Lauren Hong, Tian Wang, Connor Monticello, Natalia Lopez-Barbosa, Sophia Vincoff, Vivian Yudistyra, Lin Zhao, Elena Haarer, Tianlai Chen, Sarah Pertsemlidis, Kalyan Palepu, Suhaas Bhat, Jayani Christopher, Xinning Li, Tong Liu, Sue Zhang, Lillian Petersen, Matthew P. DeLisa, Pranam Chatterjee

“…Abstract Protein-protein interactions (PPIs) are critical for biological processes and predicting the sites of these interactions is useful for both…”
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PepMLM: Target Sequence-Conditioned Generation of Therapeutic Peptide Binders via Span Masked Language Modeling by Chen, Tianlai, Dumas, Madeleine, Watson, Rio, Vincoff, Sophia, Peng, Christina, Zhao, Lin, Hong, Lauren, Pertsemlidis, Sarah, Shaepers-Cheu, Mayumi, Wang, Tian Zi, Srijay, Divya, Monticello, Connor, Vure, Pranay, Pulugurta, Rishab, Kholina, Kseniia, Goel, Shrey, DeLisa, Matthew P, Truant, Ray, Aguilar, Hector C, Chatterjee, Pranam

“…Target proteins that lack accessible binding pockets and conformational stability have posed increasing challenges for drug development. Induced proximity…”
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Sedimentary and OSL dating evidence for the development of the present Hobq desert landscape, northern China by Fan, YuXin, Chen, XiaoLong, Fan, TianLai, Jin, Ming, Liu, JianBao, Chen, FaHu

“…The sedimentary sequence and landscape of the Hobq desert was observed through twelve profiles along five N-S sections ex- tending through the entire desert…”
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