Search Results - "Chen, Suning"

Intranasal Delivery of Copper Oxide Nanoparticles Induces Pulmonary Toxicity and Fibrosis in C57BL/6 mice by Lai, Xiaofeng, Zhao, Hu, Zhang, Yong, Guo, Kai, Xu, Yuqiao, Chen, Suning, Zhang, Jian

“…Copper oxide nanoparticles (CuO NPs) are widely used as catalysts or semiconductors in material fields. Recent studies have suggested that CuO NPs have adverse…”
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Autophagy is a therapeutic target in anticancer drug resistance by Chen, Suning, Rehman, Sumaiyah K., Zhang, Wei, Wen, Aidong, Yao, Libo, Zhang, Jian

“…Autophagy is a type of cellular catabolic degradation response to nutrient starvation or metabolic stress. The main function of autophagy is to maintain…”
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Curcumin against gastrointestinal cancer: A review of the pharmacological mechanisms underlying its antitumor activity by Fan, Yuanyuan, Zhang, Xiqin, Tong, Yuxin, Chen, Suning, Liang, Jingjing

“…Gastrointestinal cancer (GIC) poses a serious threat to human health globally. Curcumin (CUR), a hydrophobic polyphenol extracted from the rhizome of Curcuma…”
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Development and validation of a cuproptosis-related prognostic model for acute myeloid leukemia patients using machine learning with stacking by Wang, Xichao, Sun, Hao, Dong, Yongfei, Huang, Jie, Bai, Lu, Tang, Zaixiang, Liu, Songbai, Chen, Suning

“…Our objective is to develop a prognostic model focused on cuproptosis, aimed at predicting overall survival (OS) outcomes among Acute myeloid leukemia (AML)…”
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Novel Chemicals Derived from Tadalafil Exhibit PRMT5 Inhibition and Promising Activities against Breast Cancer by Yang, Ziyan, Xiao, Tian, Li, Zezhi, Zhang, Jian, Chen, Suning

“…Breast cancer seriously endangers women's health worldwide. Protein arginine methyltransferase 5 (PRMT5) is highly expressed in breast cancer and represents a…”
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PD-1 blockade immunotherapy as a successful rescue treatment for disseminated adenovirus infection after allogeneic hematopoietic stem cell transplantation by Zhou, Fei, Du, Feng, Wang, Ziyan, Xue, Mengxing, Wu, Depei, Chen, Suning, He, Xuefeng

“…Disseminated adenovirus infection is a complication with a relatively high mortality rate among patients undergoing hematopoietic stem cell transplantation…”
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Bafilomycin A1 targets both autophagy and apoptosis pathways in pediatric B-cell acute lymphoblastic leukemia by Yuan, Na, Song, Lin, Zhang, Suping, Lin, Weiwei, Cao, Yan, Xu, Fei, Fang, Yixuan, Wang, Zhen, Zhang, Han, Li, Xin, Wang, Zhijian, Cai, Jinyang, Wang, Jian, Zhang, Yi, Mao, Xinliang, Zhao, Wenli, Hu, Shaoyan, Chen, Suning, Wang, Jianrong

“…B-cell acute lymphoblastic leukemia is the most common type of pediatric leukemia. Despite improved remission rates, current treatment regimens for pediatric…”
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Case Report: A novel FGFR1 fusion in acute B-lymphoblastic leukemia identified by RNA sequencing by Zhang, Zhibo, Zhu, Yiyan, Wang, Zheng, Zeng, Zhao, Wen, Lijun, Zhang, Ling, Chen, Suning

“…8p11 myeloproliferative syndrome is a rare hematological malignancy with aggressive course caused by the various translocation of FGFR1 . In this study, a…”
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Identification of immune subtypes of Ph-neg B-ALL with ferroptosis related genes and the potential implementation of Sorafenib by Hong, Yang, Zhang, Ling, Tian, Xiaopeng, Xiang, Xin, Yu, Yan, Zeng, Zhao, Cao, Yaqing, Chen, Suning, Sun, Aining

“…The clinical outcome of Philadelphia chromosome-negative B cell acute lymphoblastic leukemia (Ph-neg B-ALL) varies considerably from one person to another…”
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Olverembatinib (HQP1351), a well-tolerated and effective tyrosine kinase inhibitor for patients with T315I-mutated chronic myeloid leukemia: results of an open-label, multicenter phase 1/2 trial by Jiang, Qian, Li, Zongru, Qin, Yazhen, Li, Weiming, Xu, Na, Liu, Bingcheng, Zhang, Yanli, Meng, Li, Zhu, Huanling, Du, Xin, Chen, Suning, Liang, Yang, Hu, Yu, Liu, Xiaoli, Song, Yongping, Men, Lichuang, Chen, Zi, Niu, Qian, Wang, Hengbang, Lu, Ming, Yang, Dajun, Zhai, Yifan, Huang, Xiaojun

“…BCR-ABL1 mutations confer resistance to tyrosine kinase inhibitors (TKIs) in chronic myeloid leukemia (CML). Olverembatinib is a new potent BCR-ABL1 TKI with…”
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Dose-escalating ruxolitinib for refractory hemophagocytic lymphohistiocytosis by Song, Yue, Li, Xiaoli, He, Xuefeng, Zhou, Fei, Du, Feng, Wang, Ziyan, Chen, Suning, Wu, Depei

“…Hemophagocytic lymphohistiocytosis (HLH) is a severe disorder characterized by excessive secretion of cytokines. Even with the recommended HLH-94/2004 regimen,…”
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The clinical application of SNP-based next-generation sequencing (SNP-NGS) for evaluation of chimerism and microchimerism after HLA-mismatched stem cell microtransplantation by Li, Weiyang, Xu, Yi, Feng, Yufeng, Zhou, Haixia, Ma, Xiao, Wu, Depei, Chen, Suning, Sun, Aining

“…Genetic diagnostic methods for evaluation of chimerism after HSCT, such as STR-PCR and XY-FISH, have limited sensitivity. When donor chimerism is in the micro…”
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The differential effects of tumor burdens on predicting the net benefits of ssCART-19 cell treatment on r/r B-ALL patients by Li, Minghao, Xue, Sheng-Li, Tang, Xiaowen, Xu, Jiayu, Chen, Suning, Han, Yue, Qiu, Huiying, Miao, Miao, Xu, Nan, Tan, Jingwen, Kang, Liqing, Yu, Zhou, Lou, Xiaoyan, Xu, Yang, Chen, Jia, Yan, Zhiqiang, Feng, Weixing, Wu, Depei, Yu, Lei

“…The tumor burden (TB) is significantly related to the severity of cytokine release syndrome (CRS) caused by CAR-T cells, but its correlation with therapeutic…”
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Clinical and molecular features of acute promyelocytic leukemia with variant retinoid acid receptor fusions by Wen, Lijun, Xu, Yang, Yao, Li, Wang, Nana, Wang, Qinrong, Liu, Tianhui, Pan, Jinlan, Cen, Jiannong, Zhou, Huifeng, Miao, Miao, Shao, Yang W, Wang, Xiaonan, Wang, Xiaoxia, Ruan, Changgeng, Wu, Depei, Chen, Suning

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Clinical, immunophenotypic, cytogenetic, and molecular genetic features in 117 adult patients with mixed-phenotype acute leukemia defined by WHO-2008 classification by Yan, Lingzhi, Ping, Nana, Zhu, Mingqing, Sun, Aining, Xue, Yongquan, Ruan, Changgeng, Drexler, Hans G, Macleod, Roderick A F, Wu, Depei, Chen, Suning

“…Among 4,780 consecutive adult acute lymphoblastic/myeloblastic leukemia patients, we identified 117 (2.4%) patients with mixed-phenotype acute leukemia…”
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Epstein–Barr virus reactivation after allogeneic hematopoietic stem cell transplantation: multifactorial impact on transplant outcomes by Ru, Yuhua, Zhang, Xiang, Song, Tiemei, Ding, Yiyang, Zhu, Ziling, Fan, Yi, Xu, Yang, Sun, Aining, Qiu, Huiying, Jin, Zhengming, Tang, Xiaowen, Han, Yue, Fu, Zhengzheng, Chen, Suning, Ma, Xiao, Chen, Feng, Chen, Jia, Wu, Depei

“…Epstein–Barr virus (EBV) reactivation after allogeneic hematopoietic cell transplantation (allo-HCT) is one of the major concerns that may lead to fatal EBV…”
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Clinical characteristics and prognostic analysis of acute myeloid leukemia patients with PTPN11 mutations by Sun, Yueyue, Zhang, Fenghong, Huo, Li, Cai, Wenzhi, Wang, Qinrong, Wen, Lijun, Yan, Lingzhi, Shen, Hongjie, Xu, Xiaoyu, Chen, Suning

“…Little is known about the clinical impact of germline/somatic mutations of PTPN11 in acute leukemia. The aim of this study was to investigate the clinical…”
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Prognostic impact of PRDM16 expression in acute myeloid leukemia with normal cytogenetics by Xiang, Xin, Lu, Qiongyu, Xu, Xiaoyu, Cai, Ping, Chen, Suning, Pan, Jinlan, Zeng, Zhao

“…Cytogenetically normal acute myeloid leukemia (CN-AML) is a heterogeneous disease with variable clinical outcomes. The identification of potential biomarkers…”
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Clinical and molecular characteristics of acute myeloid leukemia with MPL mutation by Chen, Yu, Xie, Jundan, Shen, Zhen, Shi, Jie, Chen, Suning, Wang, Gang

“…The current study aimed to explore the incidence of MPL mutations and the clinical and molecular characteristics of AML with MPL mutation. In total, 1509…”
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Case report: Identification of a novel HNRNPC::RARG fusion in acute promyelocytic leukemia lacking RARA rearrangement by Ding, Wenjing, Weng, Guangyang, Wang, Zheng, Guo, Yusha, Wang, Man, Shen, Hongjie, Chen, Suning, Du, Xin, Wen, Lijun

“…Acute promyelocytic leukemia (APL) is a special subtype of acute myeloid leukemia (AML), 95% patients have PML-RARA fusion gene as a result of a reciprocal…”
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