Search Results - "Chen, Shaoyi"

Nanoparticles Targeting and Remodeling Tumor Microenvironment for Cancer Theranostics by Lin, Gan, Chen, Shaoyi, Mi, Peng

“…The tumor microenvironment (TME) is featured with aberrant vasculatures, specific physiological parameters, viscoelastic extracellular matrix and stromal…”
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Tumor-associated macrophages promote cholangiocarcinoma progression via exosomal Circ_0020256 by Chen, Shaoyi, Chen, Zuxiao, Li, Zongyan, Li, Shiying, Wen, Zilong, Cao, Liangqi, Chen, Yubin, Xue, Ping, Li, Haiyan, Zhang, Dawei

“…This study investigated the exosomal circular RNAs (CircRNAs) produced by tumor-associated macrophages and delivered into the microenvironment of…”
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A Hoechst Reporter Enables Visualization of Drug Engagement In Vitro and In Vivo: Toward Safe and Effective Nanodrug Delivery by Miyazaki, Takuya, Chen, Shaoyi, Florinas, Stelios, Igarashi, Kazunori, Matsumoto, Yu, Yamasoba, Tatsuya, Xu, Ze-Qi, Wu, Herren, Gao, Changshou, Kataoka, Kazunori, Christie, R. James, Cabral, Horacio

“…Assessment of drug activation and subsequent interaction with targets in living tissues could guide nanomedicine design, but technologies enabling insight into…”
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Capnographic monitoring reduces hypoxia incidence in older patients undergoing gastrointestinal endoscopy under propofol sedation: study protocol for a multicenter randomized controlled trial by Lian, Qiuyue, Chen, Shaoyi, Cheng, Xiangyang, Zhang, Jie, Yu, Weifeng, Zhou, Renlong, Su, Diansan

“…Hypoxia is a very common adverse event that occurs during gastrointestinal endoscopy under sedation, especially in older patients, owing to limited reservation…”
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N1‐methylpseudouridine modification level correlates with protein expression, immunogenicity, and stability of mRNA by Chen, Shaoyi, Liu, Zheng, Cai, Jingsheng, Li, Haoran, Qiu, Mantang

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GSDMD deficiency ameliorates hyperoxia-induced BPD and ROP in neonatal mice by Sonny, Sarah, Yuan, Huijun, Chen, Shaoyi, Duncan, Matthew R., Chen, Pingping, Benny, Merline, Young, Karen, Park, Kevin K., Schmidt, Augusto F., Wu, Shu

“…Bronchopulmonary dysplasia (BPD) and retinopathy of prematurity (ROP) are among the most common morbidities affecting extremely premature infants who receive…”
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GSDMD gene knockout alleviates hyperoxia-induced hippocampal brain injury in neonatal mice by Challa, Naga Venkata Divya, Chen, Shaoyi, Yuan, Huijun, Duncan, Matthew R, Moreno, William Javier, Bramlett, Helen, Dietrich, W Dalton, Benny, Merline, Schmidt, Augusto F, Young, Karen, Wu, Shu

“…Neonatal hyperoxia exposure is associated with brain injury and poor neurodevelopment outcomes in preterm infants. Our previous studies in neonatal rodent…”
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Effects of ambient air pollution, fresh fruit and vegetable intakes as well as maternal psychosocial stress on the outcome of newborn otoacoustic emission hearing screening by Chen, Bingzhi, Chen, Shaoyi, Duan, Lidan, Zhang, Muyang, Liu, Xiaoqun, Duan, Yanying

“…Newborn hearing screening results indicated that more than 40% of the detected infants had no recognized risk factors. To determine whether maternal exposure…”
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Hyperoxia-activated circulating extracellular vesicles induce lung and brain injury in neonatal rats by Ali, Anum, Zambrano, Ronald, Duncan, Matthew R., Chen, Shaoyi, Luo, Shihua, Yuan, Huijun, Chen, Pingping, Benny, Merline, Schmidt, Augusto, Young, Karen, Kerr, Nadine, de Rivero Vaccari, Juan Pablo, Keane, Robert W., Dietrich, W. Dalton, Wu, Shu

“…Hyperoxia-induced lung injury plays a key role in the development of bronchopulmonary dysplasia (BPD), characterized by inflammatory injury and impaired lung…”
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The applications and techniques of organoids in head and neck cancer therapy by Qi, Hao, Tan, Xiaolin, Zhang, Wenshuo, Zhou, Yihong, Chen, Shaoyi, Zha, Dasong, Wang, Siyang, Wen, Jinming

“…Head and neck cancer (HNC) is one of the most common cancers on the planet, with approximately 600,000 new cases diagnosed and 300,000 deaths every year…”
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Changes in autophagy after traumatic brain injury by Liu, Cindy L, Chen, Shaoyi, Dietrich, Dalton, Hu, Bingren R

“…Autophagy is the chief machinery for bulk degradation of superfluous or aberrant cytoplasmic components. This study used the rat moderate fluid percussion…”
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Circulating extracellular vesicles activate the pyroptosis pathway in the brain following ventilation-induced lung injury by Chavez, Laura, Meguro, Julia, Chen, Shaoyi, de Paiva, Vanessa Nunes, Zambrano, Ronald, Eterno, Julia M, Kumar, Rahul, Duncan, Matthew R, Benny, Merline, Young, Karen C, Dietrich, W Dalton, Brambilla, Roberta, Wu, Shu, Schmidt, Augusto F

“…Mechanical ventilation of preterm newborns causes lung injury and is associated with poor neurodevelopmental outcomes. However, the mechanistic links between…”
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Restoring expression of tumour suppressor PTEN by engineered circular RNA‐enhanced Osimertinib sensitivity in non‐small cell lung cancer by Li, Haoran, Liu, Zheng, Chen, Shaoyi, Cai, Jingsheng, Wang, Peiyu, Chen, Kezhong, Qiu, Mantang

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A Nanoparticle Platform To Evaluate Bioconjugation and Receptor-Mediated Cell Uptake Using Cross-Linked Polyion Complex Micelles Bearing Antibody Fragments by Florinas, Stelios, Liu, Marc, Fleming, Ryan, Van Vlerken-Ysla, Lilian, Ayriss, Joanne, Gilbreth, Ryan, Dimasi, Nazzareno, Gao, Changshou, Wu, Herren, Xu, Ze-Qi, Chen, Shaoyi, Dirisala, Anjaneyulu, Kataoka, Kazunori, Cabral, Horacio, Christie, R. James

“…Targeted nanomedicines are a promising technology for treatment of disease; however, preparation and characterization of well-defined protein-nanoparticle…”
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Efficiency of donepezil in elderly patients undergoing orthopaedic surgery due to underlying post-operative cognitive dysfunction: study protocol for a multicentre randomised controlled trial by Zhu, Huichen, Cong, Lu, Chen, Yi, Chen, Shaoyi, Chen, Lingke, Huang, Zhenling, Zhou, Jie, Xiao, Jie, Huang, Yonglei, Su, Diansan

“…Post-operative cognitive dysfunction (POCD) is an overarching term used to describe cognitive impairment identified in the preoperative or post-operative…”
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CTGF disrupts alveolarization and induces pulmonary hypertension in neonatal mice: implication in the pathogenesis of severe bronchopulmonary dysplasia by Chen, Shaoyi, Rong, Min, Platteau, Astrid, Hehre, Dorothy, Smith, Heather, Ruiz, Philip, Whitsett, Jeffrey, Bancalari, Eduardo, Wu, Shu

“…The pathological hallmarks of bronchopulmonary dysplasia (BPD), one of the most common long-term pulmonary complications associated with preterm birth, include…”
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Conditional overexpression of connective tissue growth factor disrupts postnatal lung development by Wu, Shu, Platteau, Astrid, Chen, Shaoyi, McNamara, George, Whitsett, Jeffrey, Bancalari, Eduardo

“…Connective tissue growth factor (CTGF) is a member of an emerging family of immediate-early gene products that coordinates complex biological processes during…”
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Author Correction: Hyperoxia-activated circulating extracellular vesicles induce lung and brain injury in neonatal rats by Ali, Anum, Zambrano, Ronald, Duncan, Matthew R., Chen, Shaoyi, Luo, Shihua, Yuan, Huijun, Chen, Pingping, Benny, Merline, Schmidt, Augusto, Young, Karen, Kerr, Nadine, de Rivero Vaccari, Juan Pablo, Keane, Robert W., Dietrich, W. Dalton, Wu, Shu

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Controlled Fab installation onto polymeric micelle nanoparticles for tuned bioactivity by Chen, Shaoyi, Florinas, Stelios, Teitgen, Abigail, Xu, Ze-Qi, Gao, Changshou, Wu, Herren, Kataoka, Kazunori, Cabral, Horacio, Christie, R. James

“…Antibodies and antigen-binding fragments (Fabs) can be used to modify the surface of nanoparticles for enhanced target binding. In our previous work,…”
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Synthetic circRNA therapeutics: innovations, strategies, and future horizons by Cai, Jingsheng, Qiu, Zonghao, Chi‐Shing Cho, William, Liu, Zheng, Chen, Shaoyi, Li, Haoran, Chen, Kezhong, Li, Yun, Zuo, Chijian, Qiu, Mantang

“…Small molecule drugs are increasingly emerging as innovative and effective treatments for various diseases, with mRNA therapeutics being a notable…”
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