Search Results - "Chen, Shaoxian"

Monkeypox virus protein H3L induces injuries in human and mouse by Chen, Shaoxian, Huang, Guiping, Liu, Juli

“…Monkeypox virus (MPV) is known to inflict injuries and, in some cases, lead to fatalities in humans. However, the underlying mechanisms responsible for its…”
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Effect of gas compressibility on fluid field of air‐cooled turbo‐generator by Liu, Ling, Ding, Shuye, Li, Zhenjiang, Shen, Shufeng, Chen, Shaoxian, Dou, Yiping

“…The effect of gas compressibility on the fluid flow characteristics of a 350 MW air‐cooled turbo‐generator is investigated in this paper. Two gas models taking…”
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Arginine Biosynthesis Mediates Wulingzhi Extract Resistance to Busulfan-Induced Male Reproductive Toxicity by Wu, Zifang, Ma, Yuxuan, Chen, Shaoxian, Liu, Yuyan, Liu, Xianglin, Cao, Heran, Jin, Tianqi, Li, Long, Huang, Mengqi, Yang, Fangxia, Dong, Wuzi

“…Busulfan, an indispensable medicine in cancer treatment, can cause serious reproductive system damage to males as a side effect of its otherwise excellent…”
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Multi-factor regulatory network and different clusters in hypertrophic obstructive cardiomyopathy by Qin, Xianyu, Huang, Lei, Chen, Sicheng, Chen, Shaoxian, Wen, Pengju, Wu, Yueheng, Zhuang, Jian

“…Practical biosignatures and thorough understanding of regulatory processes of hypertrophic obstructive cardiomyopathy (HOCM) are still lacking. Firstly, public…”
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Panax notoginseng saponins inhibit ischemia-induced apoptosis by activating PI3K/Akt pathway in cardiomyocytes by Chen, Shaoxian, Liu, Juli, Liu, Xiaoying, Fu, Yongheng, Zhang, Mengzhen, Lin, Qiuxiong, Zhu, Jiening, Mai, Liping, Shan, Zhixin, Yu, Xiyong, Yang, Min, Lin, Shuguang

“…The panax notoginseng saponins (PNS) have been clinically used for the treatment of cardiovascular diseases and stroke in China. Evidences demonstrated that…”
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Target of rapamycin complex 1 and Tap42‐associated phosphatases are required for sensing changes in nitrogen conditions in the yeast Saccharomyces cerevisiae by Li, Jinmei, Yan, Gonghong, Liu, Sichi, Jiang, Tong, Zhong, Mingming, Yuan, Wenjie, Chen, Shaoxian, Zheng, Yin, Jiang, Yong, Jiang, Yu

“…Summary In yeast target of rapamycin complex 1 (TORC1) and Tap42‐associated phosphatases regulate expression of genes involved in nitrogen limitation response…”
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FLNC and MYLK2 Gene Mutations in a Chinese Family with Different Phenotypes of Cardiomyopathy by Qin, Xianyu, Li, Ping, Qu, Hui-Qi, Liu, Yichuan, Xia, Yu, Chen, Shaoxian, Yang, Yongchao, Huang, Shufang, Wen, Pengju, Zhou, Xianwu, Li, Xiaofeng, Wang, Yonghua, Tian, Lifeng, Hakonarson, Hakon, Wu, Yueheng, Zhuang, Jian

“…Mutations in the sarcomeric protein filamin C (FLNC) gene have been linked to hypertrophic cardiomyopathy (HCM), as they have been determined to increase the…”
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LncRNA PVT1 Knockdown Ameliorates Myocardial Ischemia Reperfusion Damage via Suppressing Gasdermin D-Mediated Pyroptosis in Cardiomyocytes by Li, Cuizhi, Song, Huafeng, Chen, Chunlin, Chen, Shaoxian, Zhang, Qiyu, Liu, Dehui, Li, Jinglong, Dong, Haojian, Wu, Yueheng, Liu, Youbin

“…Objective: Myocardial ischemia reperfusion (I/R) damage is a life-threatening vascular emergency after myocardial infarction. Here, we observed the…”
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Atypical deletion of Williams-Beuren syndrome reveals the mechanism of neurodevelopmental disorders by Zhou, Jianrong, Zheng, Ying, Liang, Guiying, Xu, Xiaoli, Liu, Jian, Chen, Shaoxian, Ge, Tongkai, Wen, Pengju, Zhang, Yong, Liu, Xiaoqing, Zhuang, Jian, Wu, Yueheng, Chen, Jimei

“…Genes associated with specific neurocognitive phenotypes in Williams-Beuren syndrome are still controversially discussed. This study identified nine patients…”
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Fn14, a Downstream Target of the TGF-β Signaling Pathway, Regulates Fibroblast Activation by Chen, Shaoxian, Liu, Juli, Yang, Min, Lai, Wen, Ye, Litong, Chen, Jing, Hou, Xinghua, Ding, Hong, Zhang, Wenwei, Wu, Yueheng, Liu, Xiaoying, Huang, Shufang, Yu, Xiyong, Xiao, Dingzhang

“…Fibrosis, the hallmark of human injuries and diseases such as serious burns, is characterized by excessive collagen synthesis and myofibroblast accumulation…”
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Analysis of genes and underlying mechanisms involved in foam cells formation and atherosclerosis development by Zhang, Kai, Qin, Xianyu, Zhou, Xianwu, Zhou, Jianrong, Wen, Pengju, Chen, Shaoxian, Wu, Min, Wu, Yueheng, Zhuang, Jian

“…Foam cells (FCs) play crucial roles in the process of all stages of atherosclerosis. Smooth muscle cells (SMCs) and macrophages are the major sources of FCs…”
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Proteomic Analysis of Hypoxia-Induced Senescence of Human Bone Marrow Mesenchymal Stem Cells by Mai, Liping, He, Guodong, Chen, Jing, Zhu, Jiening, Chen, Shaoxian, Hou, Xinghua, Yang, Hui, Zhang, Mengzhen, Wu, Yueheng, Lin, Qiuxiong, Yang, Min, Li, Xiaohong

“…Background and Aim. The senescence of human bone marrow mesenchymal stem cells (hBMSCs) can be induced by oxidative stress, but the mechanism by which it…”
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Role of the ADCY9 gene in cardiac abnormalities of the Rubinstein-Taybi syndrome by Wu, Yueheng, Xia, Yu, Li, Ping, Qu, Hui-Qi, Liu, Yichuan, Yang, Yongchao, Lin, Jijin, Zheng, Meng, Tian, Lifeng, Wu, Zhuanbin, Huang, Shufang, Qin, Xianyu, Zhou, Xianwu, Chen, Shaoxian, Liu, Yanying, Wang, Yonghua, Li, Xiaofeng, Zeng, Hanshi, Hakonarson, Hakon, Zhuang, Jian

“…Rubinstein-Taybi syndrome (RTS) is a rare, congenital, plurimalformative, and neurodevelopmental disorder. Previous studies have reported that large deletions…”
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Gender differences on perceptions of health risks and adaptation of climate change among primary healthcare workers in Guangdong Province by Li, Weibin, Yang, Lianping, Liu, Li, Liu, Yuchen, Chen, Shaoxian, Ma, Wenjun, Huang, Cunrui

“…[Background] Climate change has resulted in long-term impacts on human health. Implementing efficient adaptation strategies among primary healthcare facilities…”
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Integrated Strategies of Diverse Feature Selection Methods Identify Aging-Based Reliable Gene Signatures for Ischemic Cardiomyopathy by Song, Huafeng, Chen, Shaoze, Zhang, Tingting, Huang, Xiaofei, Zhang, Qiyu, Li, Cuizhi, Chen, Chunlin, Chen, Shaoxian, Liu, Dehui, Wang, Jiawen, Tu, Yingfeng, Wu, Yueheng, Liu, Youbin

“…Ischemic cardiomyopathy (ICM) is a major cardiovascular state associated with prominently increased morbidity and mortality. Our purpose was to detect reliable…”
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Downregulation of Uncoupling Protein 2(UCP2) Mediated by MicroRNA-762 Confers Cardioprotection and Participates in the Regulation of Dynamic Mitochondrial Homeostasis of Dynamin Related Protein1 (DRP1) After Myocardial Infarction in Mice by Liu, Dehui, Zou, Shangrong, Li, Guangnan, Zhang, Qiyu, Chen, Chunlin, Li, Cuizhi, Song, Huafeng, Chen, Shaoxian, Wang, Jiawen, Wu, Yueheng, Liu, Youbin

“…Acute myocardial infarction (MI) is one of the leading causes of death in the world, and its pathophysiological mechanisms have not been fully elucidated. The…”
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Highly Elastic Anti-fatigue and Anti-freezing Conductive Double Network Hydrogel for Human Body Sensors by Chen, Shaoxian, Huang, Jianren, Zhou, Zhaoxi, Chen, Qihui, Hong, Maochun, Yang, Shuibin, Heqing Fu

“…As a functional material, conductive hydrogel has been widely used due to its stretchability and flexibility, especially in the field of flexible wearable…”
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Trisomy 21-driven metabolite alterations are linked to cellular injuries in Down syndrome by Liu, Juli, Chen, Shaoxian, Huang, Guiping, Wen, Pengju, Zhou, Xianwu, Wu, Yueheng

“…Down syndrome (DS) arises from a genetic anomaly characterized by an extra copy of chromosome 21 (exCh21). Despite high incidence of congenital diseases among…”
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Global gene expression analysis using RNA-seq reveals the new roles of Panax notoginseng Saponins in ischemic cardiomyocytes by Chen, Shaoxian, Wu, Yueheng, Qin, Xianyu, Wen, Pengju, Liu, Juli, Yang, Min

“…Panax notoginseng saponins (PNS), the main active ingredients of Panax notoginseng (Burkill) F.H.Chen, have been clinically used for cardiovascular diseases…”
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Paternal obesity induces subfertility in male offspring by modulating the oxidative stress-related transcriptional network by Li, Long, Ma, Yuxuan, Zhu, Chao, Li, Yan, Cao, Heran, Wu, Zifang, Jin, Tianqi, Wang, Yang, Chen, Shaoxian, Dong, Wuzi

“…Background/objective The effects of fathers’ high-fat diet (HFD) on the reproductive health of their male offspring (HFD- F1) remain to be elucidated. Parental…”
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