Search Results - "Chen, Saijuan"

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    Advances in COVID-19: the virus, the pathogenesis, and evidence-based control and therapeutic strategies by Zhou, Guangbiao, Chen, Saijuan, Chen, Zhu

    Published in Frontiers of medicine (01-04-2020)
    “…Since the outbreak of the COVID-19 pandemic in early December 2019, 81 174 confirmed cases and 3242 deaths have been reported in China as of March 19, 2020…”
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    Viral and host factors related to the clinical outcome of COVID-19 by Zhang, Xiaonan, Tan, Yun, Ling, Yun, Lu, Gang, Liu, Feng, Yi, Zhigang, Jia, Xiaofang, Wu, Min, Shi, Bisheng, Xu, Shuibao, Chen, Jun, Wang, Wei, Chen, Bing, Jiang, Lu, Yu, Shuting, Lu, Jing, Wang, Jinzeng, Xu, Mingzhu, Yuan, Zhenghong, Zhang, Qin, Zhang, Xinxin, Zhao, Guoping, Wang, Shengyue, Chen, Saijuan, Lu, Hongzhou

    Published in Nature (London) (16-07-2020)
    “…In December 2019, coronavirus disease 2019 (COVID-19), which is caused by the new coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was…”
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    Protecting healthcare personnel from 2019-nCoV infection risks: lessons and suggestions by Zhang, Zhiruo, Liu, Shelan, Xiang, Mi, Li, Shijian, Zhao, Dahai, Huang, Chaolin, Chen, Saijuan

    Published in Frontiers of medicine (01-04-2020)
    “…The outbreak of a novel coronavirus disease (COVID-19, caused by the 2019-nCoV infection) in December 2019 is one of the most severe public health emergencies…”
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    Integrated analysis of gut microbiome and host immune responses in COVID-19 by Xu, Xiaoguang, Zhang, Wei, Guo, Mingquan, Xiao, Chenlu, Fu, Ziyu, Yu, Shuting, Jiang, Lu, Wang, Shengyue, Ling, Yun, Liu, Feng, Tan, Yun, Chen, Saijuan

    Published in Frontiers of medicine (01-04-2022)
    “…Emerging evidence indicates that the gut microbiome contributes to the host immune response to infectious diseases. Here, to explore the role of the gut…”
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    Cordycepin induces cell cycle arrest and apoptosis by inducing DNA damage and up-regulation of p53 in Leukemia cells by Liao, Yuanhong, Ling, Jianya, Zhang, Guoying, Liu, Fengjun, Tao, Shengce, Han, Zeguang, Chen, Saijuan, Chen, Zhu, Le, Huangying

    Published in Cell cycle (Georgetown, Tex.) (2015)
    “…Cordycepin, an adenosine analog derived from Cordyceps militaris has been shown to exert anti-tumor activity in many ways. However, the mechanisms by which…”
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    PathogenTrack and Yeskit: tools for identifying intracellular pathogens from single-cell RNA-sequencing datasets as illustrated by application to COVID-19 by Zhang, Wei, Xu, Xiaoguang, Fu, Ziyu, Chen, Jian, Chen, Saijuan, Tan, Yun

    Published in Frontiers of medicine (01-04-2022)
    “…Pathogenic microbes can induce cellular dysfunction, immune response, and cause infectious disease and other diseases including cancers. However, the cellular…”
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    Yolk sac-derived Pdcd11-positive cells modulate zebrafish microglia differentiation through the NF-κB-Tgfβ1 pathway by Yang, Ruimeng, Zhan, Ming, Guo, Miaomiao, Yuan, Hao, Wang, Yiqin, Zhang, Yiyue, Zhang, Wenqing, Chen, Saijuan, de The, Hugues, Chen, Zhu, Zhou, Jun, Zhu, Jun

    Published in Cell death and differentiation (2021)
    “…Microglia are the primary immune cells in the central nervous system, which plays a vital role in neuron development and neurodegenerative diseases. Microglial…”
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    Emerging molecular subtypes and therapeutic targets in B-cell precursor acute lymphoblastic leukemia by Li, Jianfeng, Dai, Yuting, Wu, Liang, Zhang, Ming, Ouyang, Wen, Huang, Jinyan, Chen, Saijuan

    Published in Frontiers of medicine (2021)
    “…B-cell precursor acute lymphoblastic leukemia (BCP-ALL) is characterized by genetic alterations with high heterogeneity. Precise subtypes with distinct genomic…”
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    RIG-I regulates myeloid differentiation by promoting TRIM25-mediated ISGylation by Wu, Song-Fang, Xia, Li, Shi, Xiao-Dong, Dai, Yu-Jun, Zhang, Wei-Na, Zhao, Jun-Mei, Zhang, Wu, Weng, Xiang-Qin, Lu, Jing, Le, Huang-Ying, Tao, Sheng-ce, Zhu, Jiang, Chen, Zhu, Wang, Yue-Ying, Chen, Saijuan

    “…Retinoic acid-inducible gene I (RIG-I) is up-regulated during granulocytic differentiation of acute promyelocytic leukemia (APL) cells induced by all-trans…”
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    Cellular hierarchy insights reveal leukemic stem-like cells and early death risk in acute promyelocytic leukemia by Jin, Wen, Dai, Yuting, Chen, Li, Zhu, Honghu, Dong, Fangyi, Zhu, Hongming, Meng, Guoyu, Li, Junmin, Chen, Saijuan, Chen, Zhu, Fang, Hai, Wang, Kankan

    Published in Nature communications (16-02-2024)
    “…Acute promyelocytic leukemia (APL) represents a paradigm for targeted differentiation therapy, with a minority of patients experiencing treatment failure and…”
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    Distinct immune signatures discriminate between asymptomatic and presymptomatic SARS-CoV-2pos subjects by Yu, Shanhe, Di, Caixia, Chen, Shijun, Guo, Mingquan, Yan, Jiayang, Zhu, Zhaoqin, Liu, Li, Feng, Ruixue, Xie, Yinyin, Zhang, Ruihong, Chen, Juan, Wang, Mengxi, Wei, Dong, Fang, Hai, Yin, Tong, Huang, Jinyan, Chen, Saijuan, Lu, Hongzhou, Zhu, Jiang, Qu, Jieming

    Published in Cell research (01-11-2021)
    “…Increasing numbers of SARS-CoV-2-positive (SARS-CoV-2 pos ) subjects are detected at silent SARS-CoV-2 infection stage (SSIS). Yet, SSIS represents a poorly…”
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    Clinical significance of CD34+CD117dim/CD34+CD117bri myeloblast-associated gene expression in t(8;21) acute myeloid leukemia by Li, Xueping, Dai, Yuting, Chen, Bing, Huang, Jinyan, Chen, Saijuan, Jiang, Lu

    Published in Frontiers of medicine (01-08-2021)
    “…t(8;21)(q22;q22) acute myeloid leukemia (AML) is a highly heterogeneous hematological malignancy with a high relapse rate in China. Two leukemic myeloblast…”
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    Durability of neutralizing antibodies and T-cell response post SARS-CoV-2 infection by Tan, Yun, Liu, Feng, Xu, Xiaoguang, Ling, Yun, Huang, Weijin, Zhu, Zhaoqin, Guo, Mingquan, Lin, Yixiao, Fu, Ziyu, Liang, Dongguo, Zhang, Tengfei, Fan, Jian, Xu, Miao, Lu, Hongzhou, Chen, Saijuan

    Published in Frontiers of medicine (01-12-2020)
    “…The ongoing pandemic of coronavirus disease 19 (COVID-19) is caused by a newly discovered β coronavirus named severe acute respiratory syndrome coronavirus 2…”
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    Pangenomic analysis of Chinese gastric cancer by Yu, Yingyan, Zhang, Zhen, Dong, Xiaorui, Yang, Ruixin, Duan, Zhongqu, Xiang, Zhen, Li, Jun, Li, Guichao, Yan, Fazhe, Xue, Hongzhang, Jiao, Du, Lu, Jinyuan, Lu, Huimin, Zhang, Wenmin, Wei, Yangzhen, Fan, Shiyu, Li, Jing, Jia, Jingya, Zhang, Jun, Ji, Jun, Liu, Pixu, Lu, Hui, Zhao, Hongyu, Chen, Saijuan, Wei, Chaochun, Chen, Hongzhuan, Zhu, Zhenggang

    Published in Nature communications (15-09-2022)
    “…Pangenomic study might improve the completeness of human reference genome (GRCh38) and promote precision medicine. Here, we use an automated pipeline of human…”
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    CD36 mediates SARS-CoV-2-envelope-protein-induced platelet activation and thrombosis by Tang, Zihan, Xu, Yanyan, Tan, Yun, Shi, Hui, Jin, Peipei, Li, Yunqi, Teng, Jialin, Liu, Honglei, Pan, Haoyu, Hu, Qiongyi, Cheng, Xiaobing, Ye, Junna, Su, Yutong, Sun, Yue, Meng, Jianfen, Zhou, Zhuochao, Chi, Huihui, Wang, Xuefeng, Liu, Junling, Lu, Yong, Liu, Feng, Dai, Jing, Yang, Chengde, Chen, Saijuan, Liu, Tingting

    Published in Nature communications (21-08-2023)
    “…Aberrant coagulation and thrombosis are associated with severe COVID-19 post-SARS-CoV-2 infection, yet the underlying mechanism remains obscure. Here we show…”
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