Search Results - "Chen, Ruoping"

Plasmonic silver nanoshells for drug and metabolite detection by Huang, Lin, Wan, Jingjing, Wei, Xiang, Liu, Yu, Huang, Jingyi, Sun, Xuming, Zhang, Ru, Gurav, Deepanjali D., Vedarethinam, Vadanasundari, Li, Yan, Chen, Ruoping, Qian, Kun

“…In-vitro metabolite and drug detection rely on designed materials-based analytical platforms, which are universally used in biomedical research and clinical…”
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Metabolomic Characterization of Cerebrospinal Fluid from Intracranial Bacterial Infection Pediatric Patients: A Pilot Study by Wang, Yiwen, Liu, Yu, Chen, Ruoping, Qiao, Liang

“…Intracranial bacterial infection remains a major cause of morbidity and mortality in neurosurgical cases. Metabolomic profiling of cerebrospinal fluid (CSF)…”
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Electrochemical biosensing of circulating microRNA-21 in cerebrospinal fluid of medulloblastoma patients through target-induced redox signal amplification by Wang, Chen, Liu, Yujie, Chen, Ruoping, Wang, Xiaoqiang, Wang, Yunkun, Wei, Jia, Zhang, Kun, Zhang, Chenran

“…Monitoring of cerebrospinal fluid (CSF) microRNAs (miRs) offers a promising option for the diagnosis and management of patients with central nervous system…”
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Publisher Correction: Electrochemical biosensing of circulating microRNA-21 in cerebrospinal fluid of medulloblastoma patients through target-induced redox signal amplification by Wang, Chen, Liu, Yujie, Chen, Ruoping, Wang, Xiaoqiang, Wang, Yunkun, Wei, Jia, Zhang, Kun, Zhang, Chenran

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A Role for Intestinal Endocrine Cell-Expressed G Protein-Coupled Receptor 119 in Glycemic Control by Enhancing Glucagon-Like Peptide-1 and Glucose-Dependent Insulinotropic Peptide Release by Chu, Zhi-Liang, Carroll, Chris, Alfonso, Jean, Gutierrez, Veronica, He, Hongmei, Lucman, Annette, Pedraza, Melinda, Mondala, Helen, Gao, Hui, Bagnol, Didier, Chen, Ruoping, Jones, Robert M, Behan, Dominic P, Leonard, James

“…We recently showed that activation of G protein-coupled receptor 119 (GPR119) (also termed glucose dependent insulinotropic receptor) improves glucose…”
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A Biomimetic Plasmonic Nanoreactor for Reliable Metabolite Detection by Liu, Jiangang, Cai, Chenlei, Wang, Yuning, Liu, Yu, Huang, Lin, Tian, Tongtong, Yao, Yuanyuan, Wei, Jia, Chen, Ruoping, Zhang, Kun, Liu, Baohong, Qian, Kun

“…Reliable monitoring of metabolites in biofluids is critical for diagnosis, treatment, and long‐term management of various diseases. Although widely used,…”
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Metabolic Fingerprinting on a Plasmonic Gold Chip for Mass Spectrometry Based in Vitro Diagnostics by Sun, Xuming, Huang, Lin, Zhang, Ru, Xu, Wei, Huang, Jingyi, Gurav, Deepanjali D, Vedarethinam, Vadanasundari, Chen, Ruoping, Lou, Jiatao, Wang, Qian, Wan, Jingjing, Qian, Kun

“…Current metabolic analysis is far from ideal to engage clinics and needs rationally designed materials and device. Here we developed a novel plasmonic chip for…”
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Role of GPR81 in lactate-mediated reduction of adipose lipolysis by Cai, Tian-Quan, Ren, Ning, Jin, Lan, Cheng, Kang, Kash, Shera, Chen, Ruoping, Wright, Samuel D., Taggart, Andrew K.P., Waters, M. Gerard

“…Heavy exercise or oxygen deficit often links with higher levels of arterial lactate and lower levels of plasma free fatty acids (FFA). Treatment with lactate…”
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Circulating apelin, chemerin and omentin levels in patients with gestational diabetes mellitus: a systematic review and meta-analysis by Sun, Jianran, Ren, Jiale, Zuo, Chunlin, Deng, Datong, Pan, Faming, Chen, Ruoping, Zhu, Jie, Chen, Chao, Ye, Shandong

“…The available data on the significance of circulating apelin, chemerin and omentin in women with gestational diabetes mellitus (GDM) are inconsistent. This…”
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BTBD10 inhibits glioma tumorigenesis by downregulating cyclin D1 and p-Akt by Liu, Yu, Li, Sen, Chen, Ruoping, Chen, Juxiang, Xiao, Bo, Lu, Yicheng, Liu, Jiangang

“…The aim of this study was to investigate the role of BTBD10 in glioma tumorigenesis. The mRNA and protein levels of BTBD10 in 52 glioma tissues and eight…”
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Hepatic Regenerative Potential of Mouse Bone Marrow Very Small Embryonic-Like Stem Cells by Chen, Zhi-Hua, Lv, Xin, Dai, Haiyan, Liu, Changlong, Lou, Debao, Chen, Ruoping, Zou, Gang-Ming

“…Very small embryonic‐like stem cells (VSELs) are a Sca‐1 + Lin‐CD45‐ cell population that has been isolated from the bone marrow of mice. The similarities and…”
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Establishment of a prognostic-related microRNAs risk model for glioma by bioinformatics analysis by Wang, Yunkun, Zhang, Chenran, Lu, Weiwei, Chen, Ruoping, Yu, Mingkun

“…To explore the specific prognosis related microRNAs (miRNAs) of glioma. The miRNA-Seq data and clinical information of glioma patients were downloaded from the…”
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3-(1H-Tetrazol-5-yl)-1,4,5,6-tetrahydro-cyclopentapyrazole (MK-0354): A Partial Agonist of the Nicotinic Acid Receptor, G-Protein Coupled Receptor 109a, with Antilipolytic but No Vasodilatory Activity in Mice by Semple, Graeme, Skinner, Philip J, Gharbaoui, Tawfik, Shin, Young-Jun, Jung, Jae-Kyu, Cherrier, Martin C, Webb, Peter J, Tamura, Susan Y, Boatman, P. Douglas, Sage, Carleton R, Schrader, Thomas O, Chen, Ruoping, Colletti, Steven L, Tata, James R, Waters, M. Gerard, Cheng, Kang, Taggart, Andrew K, Cai, Tian-Quan, Carballo-Jane, Ester, Behan, Dominic P, Connolly, Daniel T, Richman, Jeremy G

“…The discovery and profiling of 3-(1H-tetrazol-5-yl)-1,4,5,6-tetrahydro-cyclopentapyrazole (5a, MK-0354), a partial agonist of GPR109a, is described. Compound…”
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Nicotinic Acid Receptor Agonists Differentially Activate Downstream Effectors by Richman, Jeremy G., Kanemitsu-Parks, Martha, Gaidarov, Ibragim, Cameron, Jill S., Griffin, Peter, Zheng, Hong, Guerra, Nuvia C., Cham, Linda, Maciejewski-Lenoir, Dominique, Behan, Dominic P., Boatman, Doug, Chen, Ruoping, Skinner, Philip, Ornelas, Pricilla, Waters, M. Gerard, Wright, Samuel D., Semple, Graeme, Connolly, Daniel T.

“…Nicotinic acid remains the most effective therapeutic agent for the treatment and prevention of atherosclerosis resulting from low high density lipoprotein…”
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Corticotropin releasing factor receptor 1-deficient mice display decreased anxiety, impaired stress response, and aberrant neuroendocrine development by Smith, G W, Aubry, J M, Dellu, F, Contarino, A, Bilezikjian, L M, Gold, L H, Chen, R, Marchuk, Y, Hauser, C, Bentley, C A, Sawchenko, P E, Koob, G F, Vale, W, Lee, K F

“…Corticotropin releasing factor (CRF) is a major integrator of adaptive responses to stress. Two biochemically and pharmacologically distinct CRF receptor…”
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Analogues of Acifran:  Agonists of the High and Low Affinity Niacin Receptors, GPR109a and GPR109b by Jung, Jae-Kyu, Johnson, Benjamin R, Duong, Tracy, Decaire, Marc, Uy, Jane, Gharbaoui, Tawfik, Boatman, P. Douglas, Sage, Carleton R, Chen, Ruoping, Richman, Jeremy G, Connolly, Daniel T, Semple, Graeme

“…Recently identified GPCRs, GPR109a and GPR109b, the high and low affinity receptors for niacin, may represent good targets for the development of HDL elevating…”
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Potent tricyclic pyrazole tetrazole agonists of the nicotinic acid receptor (GPR109a) by Boatman, P. Douglas, Schrader, Thomas O., Kasem, Michelle, Johnson, Benjamin R., Skinner, Philip J., Jung, Jae-Kyu, Xu, Jerry, Cherrier, Martin C., Webb, Peter J., Semple, Graeme, Sage, Carleton R., Knudsen, Jens, Chen, Ruoping, Taggart, Andrew K., Carballo-Jane, Ester, Richman, Jeremy G.

“…Tricyclic pyrazole tetrazoles which are potent partial agonists of the high affinity niacin receptor, GPR109a, have been discovered and optimized. One of these…”
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1-Alkyl-benzotriazole-5-carboxylic Acids Are Highly Selective Agonists of the Human Orphan G-Protein-Coupled Receptor GPR109b by Semple, Graeme, Skinner, Philip J, Cherrier, Martin C, Webb, Peter J, Sage, Carleton R, Tamura, Susan Y, Chen, Ruoping, Richman, Jeremy G, Connolly, Daniel T

“…1-Substituted benzotriazole carboxylic acids have been identified as the first reported examples of selective small-molecule agonists of the human orphan…”
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5-N,N-Disubstituted 5-aminopyrazole-3-carboxylic acids are highly potent agonists of GPR109b by Skinner, Philip J., Webb, Peter J., Sage, Carleton R, Dang, Huong T., Pride, Cameron C., Chen, Ruoping, Tamura, Susan Y., Richman, Jeremy G., Connolly, Daniel T., Semple, Graeme

“…A series of novel 5-N,N-difunctionalized 5-amino pyrazole-3-carboxylic acids and their agonist activity at GPR109b are reported. A series of…”
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Expression Cloning of a Human Corticotropin-Releasing-Factor Receptor by RUOPING CHEN, LEWIS, K. A, PERRIN, M. H, VALE, W. W

“…Corticotropin-releasing factor (CRF) is the principal neuroregulator of the hypothalamic-pituitary-adrenocortical axis and plays an important role in…”
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